TenX Biopharma signs Clinical Trial Agreement with NCI

TenX Biopharma, Inc., announced today it has signed a Clinical Trial Agreement with the National Cancer Institute (NCI) to conduct an investigator sponsored Phase II clinical trial.

For this study, the NCI's Surgery Branch Chief, Dr. Steven A. Rosenberg, will lead a Phase II clinical trial investigating the combination of TenX Biopharma's zanolimumab, an investigational anti-CD4 therapeutic antibody, with aldesleukin (IL-2) for the treatment of metastatic melanoma and renal cell carcinoma.

"The activity of zanolimumab in combination treatments for cancer may provide a new therapeutic option to help patients counter these aggressive diseases.  This initiative under Dr. Rosenberg at the NCI to generate additional data will contribute significantly to the field of immune modulation in oncology," said Gardiner Smith, CEO of TenX Biopharma.

"We are delighted that TenX is participating in such an important trial, which may have far reaching implications for zanolimumab in cancer therapeutics beyond its current use with T cell lymphomas," said Asher Nathan, President of TenX Biopharma.

Zanolimumab is hoped to reduce CD4+ T regulatory cells, and may increase therapeutic effectiveness of IL-2, which is an approved therapy.

Source:

TenX Biopharma, Inc.

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