Immune System News and Research

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Osteoporosis? Look out for depression

A review article which is published in the current issue of the European Journal Psychotherapy and Psychosomatics analyzes the relationship between depression and bone metabolism.

19 Jan 2009

New approach to treat advanced melanoma

Skin cancer patient Debra Gardocki receives an injection from oncologist Dr. Sanjiv Agarwala as part of a study exploring a new approach to treat advanced melanoma -- an often fatal form of cancer for which there are limited effective treatment options.

19 Jan 2009

Probiotics prevent IgE-associated allergy until age 5 in cesarean-delivered children but not in total cohort

According to a recent study from the University and the University Central Hospital of Helsinki, Finland, no allergy-preventive effect is extended to age 5 years by perinatal supplementation with probiotics in babies at risk for developing allergies; protection is conferred only to Cesarean section babies.

15 Jan 2009

Advaxis wins European patent case involving Lovaxin-C vaccine

The European Patent Court in Munich, Germany has ruled in favor of Advaxis Incorporated and reversed a patent challenge made by Anza Therapeutics, Inc., formerly Cerus Corp.

15 Jan 2009

Pediatric vaccine propels sharp drop in meningitis cases

A pediatric vaccine with University of Rochester roots has proven to be highly successful at reducing cases of bacterial meningitis across all age groups.That is the conclusion of a seven-year study, the results of which appeared today in the New England Journal of Medicine.

14 Jan 2009

New folate antagonists selectively target pathway important in rheumatoid arthritis

Methotrexate (MTX), a folate antagonist that blocks folic acid activity, is the most widely used disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis.

13 Jan 2009

Gene therapy kills brain tumors through selective recruitment of immune cells

Scientists seeking to harness the power of the immune system to eradicate brain tumors face two major hurdles: recruiting key immune cells called dendritic cells into areas of the brain where they are not naturally found and helping them recognize tumor cells as targets for attack.

13 Jan 2009

Natural 'defence' gene reveals how oestrogen fuels cancer

CANCER RESEARCH UK scientists have shown for the first time how a natural 'defence' gene involved in fighting infections such as common colds, can be triggered by hormones to ignite and drive cancers like breast, ovarian, and possibly prostate cancer. Their findings are published in the Journal of Experimental Medicine.

13 Jan 2009

Discovery of new regulatory circuit controlling immune cell production in mice

Using a mouse model, researchers have shown that elevated levels of a small protein known as interleukin 7 (IL-7) plays a central role in regulating the production of a type of white blood cell that is required for effective immune responses.

12 Jan 2009

New mouse model for peanut allergy

Chicago researchers report the development of a new mouse model for food allergy that mimics symptoms generated during a human allergic reaction to peanuts.

12 Jan 2009

Researchers solve structure of key Ebola protein

Research led by Iowa State University scientists has them a step closer to finding a way to counter the Ebola virus.

12 Jan 2009

Less than seven hours of sleep may mean more colds

Individuals who get less than seven hours of sleep per night appear about three times as likely to develop respiratory illness following exposure to a cold virus as those who sleep eight hours or more, according to a report in the January 12 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

12 Jan 2009

New hope for transplant recipients and AIDS patients

A researcher from the Université de Montréal and the Maisonneuve-Rosemont Hospital has discovered the mechanism that prevents the regeneration of CD4+ T lymphocytes, which are white cells that are required for the proper functioning of the immune system.

12 Jan 2009

Bristol-Myers Squibb and ZymoGenetics to collaborate on hepatitis C compound

Bristol-Myers Squibb and ZymoGenetics, Inc. have announced a global collaboration for PEG-Interferon lambda, a novel type 3 interferon currently in Phase Ib development for the treatment of Hepatitis C, and its related development program.

12 Jan 2009

A new mechanism regulates type I interferon production in white blood cells

A study from a team of researchers led by Dr. Andrew P. Makrigiannis, Director of the Molecular Immunology Research Unit at the IRCM, has identified a new mechanism regulating interferon production.

12 Jan 2009

Tuberculosis commandeers body's defenses to gain foothold

Tuberculosis bacteria can commandeer the body's defenses in the early stages of infection and redirect them for their own offensive strategies, according to results reported in the scientific journal, Cell.

9 Jan 2009

Discovery of better treatment for bacterial pneumonia

Scientists at St. Jude Children's Research Hospital have demonstrated a more effective treatment for bacterial pneumonia following influenza.

9 Jan 2009

Researchers find link between two aging pathways in mice

Two previously identified pathways associated with aging in mice are connected, say researchers at the Stanford University School of Medicine.

9 Jan 2009

Researchers trick bone marrow into releasing mesenchymal stem cells

Scientists have tricked bone marrow into releasing extra adult stem cells into the bloodstream, a technique that they hope could one day be used to repair heart damage or mend a broken bone, in a new study published today in the journal Cell Stem Cell.

9 Jan 2009

Novel low-cost immunotherapy for cancer cells

Molecules of sugar sitting on the surface of cancer cells are keys to the development of a new vaccine aimed at both treating and stopping the spread of certain types of cancers called carcinomas, which include prostate, breast, ovarian and lung, among others.

8 Jan 2009