Immune System News and Research

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Tumors use enzyme to recruit regulatory T-cells and suppress immune response

One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say.

17 Aug 2007

We need to treat cancer like an infectious disease

Among the many medical miracles produced by science over the years, vaccines and antibiotics have undoubtedly saved the most lives.

17 Aug 2007

Organ-transplant drug may help fight lupus

A compound related to a drug used in humans to prevent organ-transplant rejection attacks a key biochemical process in the faulty immune cells of lupus-prone mice, suggesting a possible new approach to combating the disease, UT Southwestern Medical Center researchers have found.

17 Aug 2007

Scientists discover new mechanism for viral replication

Researchers at the University of Pennsylvania School of Medicine have identified a new strategy that Kaposi's Sarcoma Associated Herpesvirus (KSHV) uses to dupe infected cells into replicating its viral genome.

17 Aug 2007

Researchers discover how a protein modulates the inflammatory response in acute respiratory distress syndrome

Researchers at the University of Illinois at Chicago College of Medicine have discovered how a protein modulates the inflammatory response in sudden, life-threatening lung failure.

17 Aug 2007

First biomarker discovered that predicts prostate cancer outcome

Mayo Clinic researchers have identified the first immune molecule that appears to play a role in prostate cancer development and in predicting cancer recurrence and progression after surgery.

17 Aug 2007

Baxter awarded major contract for flu vaccine in the event of a pandemic

Baxter International Inc. has announced that Baxter's European subsidiary in the United Kingdom has entered into an advanced supply agreement with the Department of Health that contains an option to purchase pandemic influenza vaccine in the event the World Health Organization (WHO) declares a pandemic.

From Baxter International Inc. 17 Aug 2007

Immune deficiency linked to squamous cell eye cancer

The incidence of squamous cell eye cancer is greater among kidney transplant patients and people with human immunodeficiency virus (HIV) than the general public, which suggests the disease is associated with immune deficiency.

16 Aug 2007

Organ-transplant drug may aid in lupus fight

15 Aug 2007

Killer T cell treatment shows promise against cancers in transplant patients

Blood cell donations could be used to treat transplant patients with a particular form of cancer, according to a Cancer Research UK study reported in the journal Blood.

15 Aug 2007

MS patients given hope with new vaccine treatment

Canadian researchers have developed a vaccine to stop the progression of multiple sclerosis (MS) and they say encouraging results have already been seen.

14 Aug 2007

Metabolic cell activity directly controls life and death decisions in cells

Researchers at the University of Pennsylvania School of Medicine have found that proteins known to promote cell death are also necessary for the maturation and proliferation of immune cells.

13 Aug 2007

Gene use sets humans and chimps apart

The striking differences between humans and chimps aren't so much in the genes we have, which are 99 percent the same, but in the way those genes are used, according to new research from a Duke University team.

13 Aug 2007

Genetic engineering offers promising new approaches to improve dietary iron intake

Using selective plant breeding and genetic engineering could be used to reduce the incidence of iron deficiency worldwide by improving the quality of dietary iron, conclude authors of a Seminar in this week’s edition of The Lancet.

13 Aug 2007

New cancer stem cells could aid breast cancer research

In some ways, certain tumors resemble bee colonies, says pathologist Tan Ince. Each cancer cell in the tumor plays a specific role, and just a fraction of the cells serve as "queens," possessing the unique ability to maintain themselves in an unspecialized state and seed new tumors. These cells can also divide and produce the "worker" cells that form the bulk of the tumor.

13 Aug 2007

Cashew nut allergy more severe in children than peanut allergy

Researchers in Britain say peanut allergies may be more infamous but cashews seem to trigger more severe allergic reactions in children.

13 Aug 2007

Biomira and Merck KGaA sign agreements on Stimuvax

Biomira Inc. has announced the signing of amended and restated collaboration and supply agreements related to Stimuvax with Merck KGaA of Darmstadt, Germany.

12 Aug 2007

Researchers discover how Bcl-3 protein stops inflammation

Researchers at the University of Pennsylvania School of Medicine recently identified how a regulatory protein called Bcl-3 helps to control the body's inflammation response to infection by interfering a critical biochemical process called ubiquitination.

12 Aug 2007

New pathway for inflammation-induced cancer

A well-known inflammatory protein spawns an enzyme that inactivates two tumor-suppressing genes, ultimately triggering production of new blood vessels to nourish breast cancer cells, researchers at The University of Texas M. D. Anderson Cancer Center report in the August edition of the journal Cell .

11 Aug 2007

Scientists prepare for future pandemic strains of H5N1

Preparing vaccines and therapeutics that target a future mutant strain of H5N1 influenza virus sounds like science fiction, but it may be possible, according to a team of scientists at the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), and a collaborator at Emory University School of Medicine.

11 Aug 2007