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A microbiota-driven mechanism underlies severity of leishmaniasis infection

In a recent study posed to the medRxiv* preprint server, researchers in Brazil and the United States investigated the probable impact of the skin microbiome microbiota on the outcomes of cutaneous leishmaniasis.

8 Feb 2023

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Researchers correlate SARS-CoV-2 load and neutralizing capacity of all saliva immunoglobulins isotypes in asymptomatic individuals.

8 Feb 2023

Cellular and humoral responses and the safety of recombinant and inactivated SARS-CoV-2 vaccines in chronic kidney disease patients

Researchers investigated the B cell and humoral immune responses elicited against inactivated and recombinant SARS-CoV-2 vaccines and their safety profiles in patients with CKD.

8 Feb 2023

Researchers report two unusual COVID-19-related arrhythmic cases in children

Researchers explored the association between cardiac arrhythmias in children and COVID-19 infection.

8 Feb 2023

The effectiveness of intranasal COVID-19 vaccination in healthy adults

A recent study discusses the safety profiles and immunogenicity of the nasal BBV154 COVID-19 vaccine in healthy adults.

3 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

A new study looked at the whole spectrum of immunological reactions raised by spike and non-spike antigens following Omicron BA.1/BA.2 infections in such individuals, both with and without prior SARS-CoV-2 infection.

1 Feb 2023

Acute tubulointerstitial nephritis and uveitis in children post-COVID-19

A new study reported a novel form of post-acute coronavirus disease 2019 (COVID-19) syndrome in children.

31 Jan 2023

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Researchers investigated the CAMCI strategy as an immunotherapeutic option for inflammatory bowel disease.

31 Jan 2023

Rapid engineering of novel SARS-CoV-2 therapeutic antibodies

Researchers assessed the influence of rapid engineering of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) therapeutic antibodies to expand the neutralization spectrum.

31 Jan 2023

Study suggests robust lung mucosal immunity against SARS-CoV-2 can be better achieved through hybrid immunity, as opposed to peripheral vaccination alone

Researchers characterized immunological responses by pulmonary mucosal tissues post-COVID-19 vaccination and/or SARS-CoV-2 infection, to assess the impact of hybrid immune protection on the durability of mucosal immunological responses.

30 Jan 2023

Study evaluates SARS-CoV-2-specific antibody response in human milk

In a recent study published in the journal Communications Biology, researchers investigated the effect of the coronavirus disease 2019 (COVID-19) vaccine booster on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies in the milk of lactating women. Additionally, they explored whether the booster-induced antibody response differed from the homologous and heterologous boosting schedule of their primary vaccination.

29 Jan 2023

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

A recent study evaluates the presence of SARS-CoV-2 in children’s tonsils during the COVID-19 pandemic.

29 Jan 2023

Pregnancy has no effect on long-term immune response to SARS-CoV-2 mRNA vaccination

The immunologic milieu of pregnancy has no effect on the durability of the anti-S IgG response to COVID-19 vaccination

29 Jan 2023

Researchers uncover new mechanism that plays key role in the progression of alcohol-related liver disease

Alcohol-related liver disease is among the most common causes of morbidity and mortality worldwide. Due to an incomplete understanding of the factors contributing to disease development, liver transplantation is still the only available cure.

24 Jan 2023

Researchers identify potent pan-sarbecovirus antibodies from non-human primates vaccinated with an AS03 adjuvanted subunit SARS-CoV-2 vaccine

Researchers assessed the effectiveness of pan-sarbecovirus-neutralizing antibodies against SARS-CoV-2.

24 Jan 2023

CHLA launches first clinical trial for Down syndrome regression disorder with $5.3 million NIH grant

Children's Hospital Los Angeles has launched the first clinical trial for Down syndrome regression disorder (DSRD), a rare and debilitating condition that affects adolescents and young adults with Down syndrome.

23 Jan 2023

Study reviews mechanistic data on new methods of allergy prevention and treatment

In a recent article published in Science Translational Medicine, researchers reviewed the cause and the underlying pathophysiology of allergic diseases.

23 Jan 2023

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

Researchers evaluated immunoglobulin G (IgG) responses to coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccinations.

20 Jan 2023

Immunological interactions between asthma, obesity, and the microbiota

This study summarizes the mechanisms associated with obesity-aggravated asthma.

18 Jan 2023

Immunoglobulin News and Research

A microbiota-driven mechanism underlies severity of leishmaniasis infection

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Cellular and humoral responses and the safety of recombinant and inactivated SARS-CoV-2 vaccines in chronic kidney disease patients

Researchers report two unusual COVID-19-related arrhythmic cases in children

The effectiveness of intranasal COVID-19 vaccination in healthy adults

Researchers report a heterologous vaccination strategy against IBV in Chickens

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

Acute tubulointerstitial nephritis and uveitis in children post-COVID-19

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Rapid engineering of novel SARS-CoV-2 therapeutic antibodies

Study suggests robust lung mucosal immunity against SARS-CoV-2 can be better achieved through hybrid immunity, as opposed to peripheral vaccination alone

Study evaluates SARS-CoV-2-specific antibody response in human milk

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

Pregnancy has no effect on long-term immune response to SARS-CoV-2 mRNA vaccination

Researchers uncover new mechanism that plays key role in the progression of alcohol-related liver disease

Researchers identify potent pan-sarbecovirus antibodies from non-human primates vaccinated with an AS03 adjuvanted subunit SARS-CoV-2 vaccine

CHLA launches first clinical trial for Down syndrome regression disorder with $5.3 million NIH grant

Study reviews mechanistic data on new methods of allergy prevention and treatment

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

Immunological interactions between asthma, obesity, and the microbiota

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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