Immunomodulatory News and Research

RSS

Large cell therapy trial in patients with chronic heart failure shows promising results

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

27 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

Review: Immunomodulatory therapies and nutritional significance of Ganoderma lucidum

According to the research published in Food & Functions recently, a team led by Prof. Huang Qing at the Institute of Intelligent Machines, Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Sciences (CAS), reported for the first time an update and a comprehensive summary of the studies on the immunomodulatory therapies and nutritional significance of Ganoderma lucidum (G. lucidum) from 2010 to 2022, and confirmed that G. lucidum is an essential prebiotic for increasing bacterial flora and a health encouraging agent because of its components, primarily its abundant source of polysaccharides, triterpenoids, and polyphenols.

22 Feb 2023

Dietary polyphenols may play a role in regulating inflammatory immune responses

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

Smoking and vaping may put healthy young people at risk of severe COVID

The levels of some ADAM17 targets were elevated in the plasma of tobacco cigarette smokers as compared to non-smokers.

15 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

The National Institutes of Health has initiated a multi-site clinical trial evaluating an investigational antiviral for the treatment of COVID-19.

15 Feb 2023

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

10 Feb 2023

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

Researchers performed a multi-omics investigation of gut microbiome-host interactions and plasma metabolomics among myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients.

10 Feb 2023

The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy

Researchers reviewed the impact of endometrial microbiota on immune tolerance during pregnancy.

8 Feb 2023

Immunomodulatory antibodies found to be successful in treating cancer when they have a looser grip

New research from the Centre for Cancer Immunology at the University of Southampton, published ahead of World Cancer Day (4 February), has shown that changing how tightly an antibody binds to a target could improve treatments for cancer.

1 Feb 2023

An in-depth meta-analysis highlights COVID-19's pregnancy dangers

Researchers assess the risk of maternal, fetal, and neonatal morbidity and mortality in women diagnosed with COVID-19 during pregnancy.

17 Jan 2023

The relationship between metabolic disease and alternations in lipid homeostasis

Researchers assessed the function of lipids in metabolic diseases.

4 Jan 2023

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

29 Dec 2022

What is the importance of vitamin B12 supplementation in plant-based diets?

Researchers emphasize the importance of vitamin B12 supplementation for individuals consuming a plant-based or vegan diet.

9 Dec 2022

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Unique new material developed at University of Limerick in Ireland has shown significant promise in the treatment of spinal cord injury.

29 Nov 2022

Does breast milk influence infants' intestinal microbiota?

A large number of health-related benefits of probiotics have led to the development of a new discipline called probiogenomics, which focuses on the molecular mechanisms of probiotic activities. According to the US Food and Drug Administration (FDA), the next-generation probiotics satisfy the scope of "live biotherapeutic products" (LBPs), which could be used to develop effective therapeutics for various diseases.

28 Nov 2022

Glycan signatures in rheumatic diseases and their associated functional implications

A new paper examines the understanding of glycosylation in an array of rheumatic diseases and indicates the potential for therapeutic interventions using the same mechanism.

28 Nov 2022

New EULAR recommendations for screening and treating infections in AIIRD patients

It is already known that people who are immunocompromised are more prone to infections. Chronic and opportunistic infections are often found in people with an AIIRD, and may be linked to some of the immunosuppressive and immunomodulatory treatments used to treat these rheumatic diseases.

22 Nov 2022

Why we should all eat Kimchi and other Korean fermented foods

A recent study reviews various traditional Korean fermented foods for their various health benefits.

20 Nov 2022

Immunomodulatory News and Research

Large cell therapy trial in patients with chronic heart failure shows promising results

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

Review: Immunomodulatory therapies and nutritional significance of Ganoderma lucidum

Dietary polyphenols may play a role in regulating inflammatory immune responses

Smoking and vaping may put healthy young people at risk of severe COVID

Delayed presentation of MIS-C following COVID-19

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy

Immunomodulatory antibodies found to be successful in treating cancer when they have a looser grip

An in-depth meta-analysis highlights COVID-19's pregnancy dangers

The relationship between metabolic disease and alternations in lipid homeostasis

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

What is the importance of vitamin B12 supplementation in plant-based diets?

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Does breast milk influence infants' intestinal microbiota?

Glycan signatures in rheumatic diseases and their associated functional implications

New EULAR recommendations for screening and treating infections in AIIRD patients

Why we should all eat Kimchi and other Korean fermented foods

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

Revolutionizing Schizophrenia Research

Latest News