Immunomodulatory News and Research

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Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Researchers assess the efficacy of the human surfactant protein A against SARS-CoV-2 infectivity.

10 Apr 2023

Study explores the association between gut microbiome dysbiosis and uveitis

Researchers provide an overview of existing research on the correlation between uveitis and gut dysbiosis.

7 Apr 2023

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

A team led by engineers at the University of California San Diego has developed a biodegradable polymer system to treat rheumatoid arthritis, an autoimmune and inflammatory disease, by working in concert with the power of the human immune system.

4 Apr 2023

What is the effect of prior BCG vaccination on the immunogenicity and efficacy of subsequent COVID-19 vaccination?

Researchers assessed the impact of BCG vaccination on the protection provided by SARS-CoV-2 vaccination.

28 Mar 2023

Metformin may reduce the risk of osteoarthritis

In a recent study published in JAMA Network Open, researchers in the United States (US) determined the risk of osteoarthritis (OA) and joint replacement among adults with type 2 diabetes (T2D) following metformin or sulfonylurea treatment.

27 Mar 2023

Curcumin reduces inflammatory responses in post-COVID vaccinated adults

A new study published in the Nutrients Journal highlights the impact of curcumin supplementation on the immune response following the immunization of Coronavirus disease 2019 (COVID-19) survivors with a primary series of monovalent COVID-19 vaccines.

26 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

Researchers assessed the impact of an anti-CD3 monoclonal antibody called Foralumab in COVID-19 treatment.

9 Mar 2023

CDC recommendations and clinical considerations for the treatment of severe Mpox

In a recent article published in the United States (U.S.) Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report, a team of researchers discussed the medical countermeasures and clinical considerations for treating severe manifestations of Mpox.

6 Mar 2023

Immunomodulatory effects of biotics-supplemented infant formulas

A review article published in the journal Nutrients describes the effects and benefits of pre-, pro-, syn-, and postbiotics-containing infant formulas in terms of modulating gut microbiota, immune response, and allergy susceptibility of newborns and infants.

1 Mar 2023

Large cell therapy trial in patients with chronic heart failure shows promising results

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

27 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

Review: Immunomodulatory therapies and nutritional significance of Ganoderma lucidum

According to the research published in Food & Functions recently, a team led by Prof. Huang Qing at the Institute of Intelligent Machines, Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Sciences (CAS), reported for the first time an update and a comprehensive summary of the studies on the immunomodulatory therapies and nutritional significance of Ganoderma lucidum (G. lucidum) from 2010 to 2022, and confirmed that G. lucidum is an essential prebiotic for increasing bacterial flora and a health encouraging agent because of its components, primarily its abundant source of polysaccharides, triterpenoids, and polyphenols.

22 Feb 2023

Dietary polyphenols may play a role in regulating inflammatory immune responses

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

Smoking and vaping may put healthy young people at risk of severe COVID

The levels of some ADAM17 targets were elevated in the plasma of tobacco cigarette smokers as compared to non-smokers.

15 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

The National Institutes of Health has initiated a multi-site clinical trial evaluating an investigational antiviral for the treatment of COVID-19.

15 Feb 2023

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

10 Feb 2023

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

Researchers performed a multi-omics investigation of gut microbiome-host interactions and plasma metabolomics among myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients.

10 Feb 2023

The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy

Researchers reviewed the impact of endometrial microbiota on immune tolerance during pregnancy.

8 Feb 2023

Immunomodulatory News and Research

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Study explores the association between gut microbiome dysbiosis and uveitis

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

What is the effect of prior BCG vaccination on the immunogenicity and efficacy of subsequent COVID-19 vaccination?

Metformin may reduce the risk of osteoarthritis

Curcumin reduces inflammatory responses in post-COVID vaccinated adults

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

CDC recommendations and clinical considerations for the treatment of severe Mpox

Immunomodulatory effects of biotics-supplemented infant formulas

Large cell therapy trial in patients with chronic heart failure shows promising results

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

Review: Immunomodulatory therapies and nutritional significance of Ganoderma lucidum

Dietary polyphenols may play a role in regulating inflammatory immune responses

Smoking and vaping may put healthy young people at risk of severe COVID

Delayed presentation of MIS-C following COVID-19

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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