Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Three new genetic variations that increase the risk of obesity

The gene variant most strongly associated with childhood obesity and adult morbid obesity in the study is located near the PTER gene, the function of which is not known. This variant is estimated to account for up to a third of all childhood obesity, and a fifth of all cases of adult obesity.

19 Jan 2009

Important discovery in human insulin-producing cells

Researchers at the University of Pittsburgh School of Medicine have successfully induced human insulin-producing cells, known as beta cells, to replicate robustly in a living animal, as well as in the lab.

13 Jan 2009

Hospital diabetes care standards not met by US academic medical centers

A benchmarking study published in the Journal of Hospital Medicine evaluated contemporary hospital glycemic management in United States academic medical centers, determining glucose control practices are suboptimal and do not meet current American Diabetes Association (ADA) hospital diabetes care standards.

13 Jan 2009

Fatty liver disease medication may have no effect

A new randomized, prospective trial has shown that orlistat, a commonly prescribed inhibitor of fat absorption, does not help patients with fatty liver disease (FLD) lose weight, nor does it improve their liver enzymes or insulin resistance.

13 Jan 2009

Athletes aren't necessarily off the hook when it comes to health risks

College-age football players who gain weight to add power to their blocks and tackles might also be setting themselves up for diabetes and heart disease later in life, a new study suggests.

13 Jan 2009

Food-addiction blamed for obesity

A study by scientists in New Zealand say craving something sweet like a biscuit or piece of chocolate could be a response to an addiction.

13 Jan 2009

Vitamin D offers widespread benefits for health

Vitamin D is quickly becoming the "it" nutrient with health benefits for diseases, including cancer, osteoporosis, heart disease and now diabetes.

12 Jan 2009

New insight and intervention ideas to help reduce the number of heart attacks

A new national study has shown that nearly 75 percent of patients hospitalized for a heart attack had cholesterol levels that would indicate they were not at high risk for a cardiovascular event, according to current national cholesterol guidelines.

12 Jan 2009

Diabetes associated with different types of brain injury in patients with dementia

Patients with dementia and diabetes appear to display a different pattern of injuries in their brains than patients with dementia but without diabetes, according to an article posted online today that will appear in the March print issue of Archives of Neurology.

12 Jan 2009

Estrogen plus progestin therapy may decrease risk of colorectal cancer

The combination of estrogen plus progestin, which women stopped taking in droves following the news that it may increase their risk of breast cancer, may decrease their risk of colorectal cancer, according to a report published in the January issue of Cancer Epidemiology, Biomarkers and Prevention , a journal of the American Association for Cancer Research.

8 Jan 2009

Metabolic syndrome risk for veterans with post-traumatic stress disorder

Veterans with post-traumatic stress disorder (PTSD) are more likely to have metabolic syndrome than veterans without PTSD.

7 Jan 2009

Genomics in China

Ten years ago, the Chinese National Human Genome Center at Shanghai (South Center, hereafter) was established in the Zhangjiang HiTech Park of Pudong District in Shanghai.

7 Jan 2009

People with Ala12 gene variant need to watch out for high fat in their diets

New evidence in mice bolsters the notion that a version of a gene earlier shown to protect lean people against weight gain and insulin resistance can have the opposite effect in those who eat a high-fat diet and are heavier, reveals a report in the January 7th issue of the journal Cell Metabolism, a Cell Press publication.

6 Jan 2009

New hope for leptin as a solution to obesity

The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity.

6 Jan 2009

COUP-TFII plays pivotal role in obesity, metabolic syndrome

A protein known to play a role in development and the formation of organs is also an important factor in the control of obesity and diabetes, said researchers from Baylor College of Medicine in a report that appears in the current issue of the journal Cell Metabolism.

6 Jan 2009

Novel treatment option for obesity

A new study in the January 7th issue of Cell Metabolism , a Cell Press publication, helps to explain why obese people and animals fail to respond to leptin, a hormone produced by fat that signals the brain to stop eating.

6 Jan 2009

Researchers link blood sugar to normal cognitive aging

Maintaining blood sugar levels, even in the absence of disease, may be an important strategy for preserving cognitive health, suggests a study published by researchers at Columbia University Medical Center (CUMC).

1 Jan 2009

Researchers engineer pancreatic cell transplants to evade immune response

In a finding that could significantly influence the way type 1 diabetes is treated, researchers at Albert Einstein College of Medicine of Yeshiva University have developed a technique for transplanting insulin-producing pancreatic cells that causes only a minimal immune response in recipients.

1 Jan 2009

High-fat diet can disrupt our biological clock

Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms - everyone's 24-hour biological clock, Hebrew University of Jerusalem researchers have shown.

29 Dec 2008

Barcode chip enables cheaper, faster blood testing

A new barcode chip developed by a multi-institutional team of investigators promises to revolutionize diagnostic medical testing. In less than 10 minutes and using just a pinprick's worth of blood, the chip can measure the concentrations of dozens of proteins, including those that herald the presence of diseases such as cancer and heart disease.

29 Dec 2008