Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Examining the interplay between diet, glucose metabolism and sleep

Researchers summarized the inter-relationship between diet, glucose metabolism, and sleep.

2 May 2023

Study finds increased prevalence of hypertension among people with severe obesity and a genetic variant

Obesity and its associated cardiometabolic issues are a major health concern in the U.S. and internationally.

19 Apr 2023

Mouse studies can help find better therapeutic targets for people with PCOS

Polycystic ovarian syndrome, or PCOS, can cause a range of symptoms, including disrupted menstrual cycles, abdominal obesity, cardiovascular disease, and type 2 diabetes.

18 Apr 2023

Is there a correlation between acute and chronic red wine intake and health?

Researchers examined the correlations between acute and chronic red wine (RW) intake and health.

18 Apr 2023

Study finds sugary beverages increase dementia risk, while natural juices may help prevent it

Sugary beverages were associated with a higher risk of dementia, whereas moderate intake of natural juices was associated with a lower dementia risk.

17 Apr 2023

Factors shaping maternal gut microbiome during pregnancy and the impact on infant health

In an article published in the journal Current Opinion in Microbiology, scientists have provided a detailed overview of the factors affecting maternal gut microbiota during pregnancy and its impact on maternal and infant health.

17 Apr 2023

Pathophysiology, comorbidities, and interventions related to childhood obesity

Researchers discuss the psychological and physiological impacts of obesity on children.

6 Apr 2023

The impact of perinatal low-calorie sweetener exposure on the development of neural systems involved in metabolic regulation

A study published in the Journal of Clinical Investigation Insight reveals that consumption of low-calorie sweeteners during pregnancy can affect the metabolism and neural development of the offspring.

6 Apr 2023

Birth weight and maternal BMI modify the relationship between obesity and mortality rate

Obesity is a significant risk factor for premature mortality due to the predisposition to metabolic and cardiovascular disease. However, is this effect independent of the birth weight? A new research paper examines this aspect of adult obesity, measuring the effect of parental body mass index (BMI) and birth weight on the mortality risk.

3 Apr 2023

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Researchers reviewed existing literature on the benefits of adopting Mediterranean diets against inflammatory conditions and cancer.

3 Apr 2023

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

Researchers explored the correlation between autoimmunity and obesity.

3 Apr 2023

New microscopy method illuminates the mechanics of embryo development

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon – when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging some energy in the process.

30 Mar 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

Maternal weight gain in pregnancy linked to children's risk of neurodevelopmental disorders

In a recent study published in the BMC Medicine journal, researchers in Sweden explored the association between above-optimal maternal gestational weight gain (GWG) and the risk of neurodevelopmental disorders such as intellectual disability, autism spectrum disorder (ASD), and attention-deficit/hyperactivity disorder (ADHD) in offspring.

29 Mar 2023

Biological BMI measures metabolic health more accurately

Researchers analyze longitudinal and cross-sectional changes in blood analytes associated with variations in body mass index.

23 Mar 2023

Childhood and adolescent obesity: time to act

In a recent review published in the journal Frontiers in Pediatrics, researchers at the Medical College of Wisconsin presented an overview of the pathophysiological mechanisms, health implications, and management options for obesity among children and adults.

21 Mar 2023

Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

20 Mar 2023

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese mouse model. Therefore, the precise effects exerted by GIP and GIPRAs remain elusive.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

How gut microbiota control feelings of fullness after eating

A recent study discusses recent findings linking satiety to the gut microbiome.

7 Mar 2023

Leptin News and Research

Further Reading

Examining the interplay between diet, glucose metabolism and sleep

Study finds increased prevalence of hypertension among people with severe obesity and a genetic variant

Mouse studies can help find better therapeutic targets for people with PCOS

Is there a correlation between acute and chronic red wine intake and health?

Study finds sugary beverages increase dementia risk, while natural juices may help prevent it

Factors shaping maternal gut microbiome during pregnancy and the impact on infant health

Pathophysiology, comorbidities, and interventions related to childhood obesity

The impact of perinatal low-calorie sweetener exposure on the development of neural systems involved in metabolic regulation

Birth weight and maternal BMI modify the relationship between obesity and mortality rate

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

New microscopy method illuminates the mechanics of embryo development

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Maternal weight gain in pregnancy linked to children's risk of neurodevelopmental disorders

Biological BMI measures metabolic health more accurately

Childhood and adolescent obesity: time to act

Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

How gut microbiota control feelings of fullness after eating

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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