Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Study paves the way to new sex-specific anti-obesity drugs

Sex differences exist in the regulation of energy homeostasis, the organism's mechanism to keep a stable body weight. Current studies indicate for instance that female mammals, including humans, are better protected against metabolic diseases during reproductive age.

7 Mar 2023

Pennington Biomedical assistant professor seeks to better understand why people with diabetes develop hypoglycemia

For someone with type 1 diabetes, it's imperative they test their blood sugar levels regularly, and insulin is utilized to keep blood sugar regulated.

23 Feb 2023

Immunological interactions between asthma, obesity, and the microbiota

This study summarizes the mechanisms associated with obesity-aggravated asthma.

18 Jan 2023

Correlating circulating adipokine levels with COVID-19 severity

Researchers determine whether plasma adipokine levels were associated with COVID-19-related systemic inflammation and severity.

14 Dec 2022

Stem cell crosstalk with the microenvironment creates a loop of tumor-promoting factors

What drives tumor growth? Is it a few rogue cells imposing their will upon healthy tissue, or diseased tissue bringing out the worst in otherwise peaceable cells? Or is it a back-and-forth, a dialogue between the two?

30 Nov 2022

Gut microbiome plays a role in Alzheimer's

In a recent review published in the journal Pharmacological Research, researchers in Brazil investigated the role of gut microbiota in cognition, brain function, behavior, and neurodegenerative disease pathogenesis.

17 Nov 2022

Ketogenic diet may show more promising results than Mediterranean diets in short-term type 2 diabetes management

Researchers evaluated the short-term impact of the very-low-calorie ketogenic diet (VLCKD) and Mediterranean diet (MD) on the gut microbiota (GM) of obese patients with new-onset type II diabetes (T2DM).

15 Nov 2022

Johns Hopkins researchers uncover a possible target to treat sleep apnea

In a new study with obese mice, Johns Hopkins Medicine researchers say they have added to evidence that specialized channel proteins are possible therapeutic targets for sleep apnea and similar abnormally slow breathing disorders in obese people.

31 Oct 2022

Rheumatoid arthritis drug can be repurposed to improve diabetes-associated symptoms

Researchers at Baylor College of Medicine and collaborating institutions discovered that the rheumatoid arthritis drug auranofin can potentially be repurposed to improve diabetes-associated symptoms.

14 Oct 2022

Study opens up new approaches for treating fatty liver disease

A study group at MedUni Vienna has identified a regulatory loop controlled by leptin, by which this adipocyte-derived hormone regulates hepatic lipid metabolism via the autonomic nervous system.

11 Oct 2022

Does leptin play a role in Parkinson’s disease?

Scientists review in vitro and in vivo evidence associated with Parkinson's disease and leptin.

26 Sep 2022

Excessive smartphone use may lead to early puberty

Exposure to blue light via regular use of tablets and smartphones may alter hormone levels and increase the risk of earlier puberty, according to data from a rat study presented today at the 60th Annual European Society for Paediatric Endocrinology Meeting.

16 Sep 2022

Leptin News and Research

Further Reading

Study paves the way to new sex-specific anti-obesity drugs

Pennington Biomedical assistant professor seeks to better understand why people with diabetes develop hypoglycemia

Immunological interactions between asthma, obesity, and the microbiota

Correlating circulating adipokine levels with COVID-19 severity

Stem cell crosstalk with the microenvironment creates a loop of tumor-promoting factors

Gut microbiome plays a role in Alzheimer's

Ketogenic diet may show more promising results than Mediterranean diets in short-term type 2 diabetes management

Johns Hopkins researchers uncover a possible target to treat sleep apnea

Rheumatoid arthritis drug can be repurposed to improve diabetes-associated symptoms

Study opens up new approaches for treating fatty liver disease

Does leptin play a role in Parkinson’s disease?

Excessive smartphone use may lead to early puberty

Obese children who recently lost weight more likely to show hunger-related brain activity after a meal

Eating disorders could be treated by modulating gut microbiota

Nutritive intervention could be an effective treatment method in maintaining human health

How does obesity affect the immune system?

Midgestation increase in leptin puts child and mother at risk of cardiovascular disease

Virginia Tech scientist receives $2 million to examine the brain circuit responsible for high-fat food overconsumption

Novel therapy using nitric oxide may be an efficient and safe way to treat multiple metabolic diseases

Understanding the Choice Between Individual Versus Social Housing Mice and Its Impact On Research

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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