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Osteopontin-c: A key player in mitochondrial biogenesis and cancer metastasis

A new research paper was published in Oncotarget's Volume 14 on December 1, 2023, entitled, "Osteopontin induces mitochondrial biogenesis in deadherent cancer cells."

5 Dec 2023

Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

Chitosan tamponades: A breakthrough in treating postpartum hemorrhage

Researchers highlight chitosan-covered tamponades as a promising, accessible treatment for postpartum hemorrhage, a major cause of maternal mortality, especially where advanced medical interventions are unavailable. This method, safe and effective, offers a crucial option in emergency situations, as detailed in their study, including application guidelines and a demonstration video.

23 Nov 2023

New diagnostic workflow improves detection of 5q-spinal muscular atrophy

5q-spinal muscular atrophy (5q-SMA) is one of the more common types of spinal muscular atrophy (SMA) affecting around one in ten thousand individuals worldwide.

15 Nov 2023

Researchers improve the system for stratifying mortality risk of variceal bleeding

Approximately half of patients with advanced liver disease have varicose veins in the esophagus and stomach, and a more than a fifth of them experience bleeding from these varices into the digestive tract.

13 Nov 2023

International report paves way for precision diabetes medicine breakthrough

Precision medicine for prevention, diagnosis, treatment, and prognosis for Diabetes.

9 Oct 2023

Cerebrospinal fluid leaks may be one of the mechanisms that link TBI with dementia

Cerebrospinal fluid (CSF) leaks may be one of the mechanisms that link traumatic brain injury (TBI) with dementia, according to a recently published hypothesis in Alzheimer's & Dementia: Translational Research & Clinical Interventions, a journal of the Alzheimer's Association.

21 Sep 2023

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

New female contraceptive under development: end-user preferences revealed in web-based survey

Researchers investigated prospective end-user preferences for an on-demand, non-hormonal female contraception.

26 Jul 2023

Difficult transmembrane protein targets for therapeutic antibodies

In this interview, News-Medical talks to Sylvia Xie, product scientist at Sino Biological, about the ongoing emergence of transmembrane proteins as targets for therapeutic antibodies.

From Sino Biological Inc. 12 Jul 2023

Gynecologic procedures may be associated with increased risk of cardiovascular disease

A new study showed that hysterectomy alone, hysterectomy with oophorectomy, and tubal ligation were all associated with an increased risk of cardiovascular disease (CVD).

11 May 2023

Drugs targeting FXR1 may treat vascular proliferative diseases

Vascular diseases, including myocardial infarction, stroke, renal failure, and peripheral vascular disease, continue to account for one third of all mortality in the United States, Europe, and the developing world (World Health Organization, 2021).

2 May 2023

The Power of Solid-State Nuclear Magnetic Resonance in Biological Research

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Spectroscopy Award, Robert Tycko.

From Pittcon 20 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

For young people on Medicare, a hysterectomy sometimes is more affordable than birth control

Sam Chavarría said her doctor was clear about the birth defects her medication could cause if she became pregnant but agreed to keep her on it as long as she had an IUD.

7 Mar 2023

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

The Tecan Group and Oxford Nanopore Technologies plc (Oxford Nanopore) today announce their collaboration to drive easier high-throughput nanopore library preparation in an automated, hands-free fashion.

From Tecan 27 Feb 2023

Gut dysbiosis and sepsis susceptibility among pregnant women

Researchers describe the role of gut dysbiosis during pregnancy in promoting excessive macrophage pyroptosis, which increases vulnerability to sepsis.

19 Feb 2023

B lymphocytes play a pivotal role in promoting an emergent response during infection

An SOS signals a call for immediate action during an emergency to request a need for protection. The immune system, a network of defense mechanisms, enhances protection to recover the body's internal stability.

15 Feb 2023

Aircraft noise exposure before MI amplifies subsequent cardiovascular inflammation

Traffic noise may play an essential role in the development and deterioration of ischemic heart disease. Researchers from the Cardiology Department at the University Medical Center Mainz now discovered that noise exposure(average sound pressure level 72 dB; peak level 85 dB) up to 4d resulted in pro-inflammatory aortic gene expression in mice.