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Serum fibrosis markers correlate with liver fibrosis stage in patients with advanced chronic hep C

A prospective study of patients with advanced chronic hepatitis C (CHC) revealed that a 3-variable model of serum fibrosis markers, including serum HA, TIMP-1 and platelet count, could identify cirrhosis with better accuracy than other published models.

4 Mar 2008

Intracellular bacterial communities in cystitis; rifapentine cures TB in mouse model; and more

A study published this week in the open access journal PLoS Medicine presents convincing evidence that intracellular bacterial communities (IBCs) commonly exist in women with bladder infections and may contribute to the recurrence of these infections.

18 Dec 2007

Closest look ever at native human tissue

Seeing proteins in their natural environment and interactions inside cells has been a long-standing goal.

5 Dec 2007

Brookhaven microgrid allows simultaneous study of multiple variables

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have developed a method for correlating the results of microscopic imaging techniques in a way that could lead to improved understanding, diagnosis, and possibly treatment of a variety of disease conditions, including Alzheimer's disease. The Laboratory has filed a U.S. provisional patent application for the invention.

10 Oct 2007

Evaluation of leading combination regimens for treating malaria

Ugandan children who received the combination therapy of artemether-lumefantrine experienced a lower rate of treatment failure compared to other combination therapies, according to a study in the May 23/30 issue of JAMA , a theme issue on malaria.

24 May 2007

New mapping technique will answer fundamental questions about chromosome structure

Researchers at the University of Illinois have developed a simple and economical technique for imaging and mapping fruit fly chromosomes.

8 May 2007

Phase separation of lipid membranes analyzed with high-resolution secondary ion mass spectrometry

Understanding the chemical composition and organization of cell membranes - what components reside next to each other, how many of each there are and how they respond to their environment - may reveal the secret lives of cells in both health and disease.

9 Oct 2006

Bladder urothelium in PBS/IC shows distinct differences in keratin profiles

Research groups from the Netherlands and Denmark led by Pilar Laguna studied urothelial involvement in PBS/IC by characterizing the keratin phenotype of bladder urothelium in 18 patients with the disorder.

20 Aug 2006