Liver Cancer News and Research

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Liver cancer is more common in older people. Over half of people newly diagnosed with liver cancer are age 65 and over. Liver cancer is more common in men than in women. Liver cancer rates are highest among Asians and Pacific Islanders, most likely because of higher prevalence of viral Hepatitis infection. Liver cancer rates are lower among whites than Blacks or Asians and Pacific Islanders. At this time, we do not know exactly what causes cancer of the liver. There are several different types of liver cancer. The most common type is associated with long-term excessive alcoholic beverage use, scarring of the liver (cirrhosis), and Hepatitis B virus or Hepatitis C virus infection. Long-term use of anabolic steroids can also increase the risk of getting liver cancer. Smoking is also believed to increase the risk of getting liver cancer.

Liver cancer can be recognized by RNA fragments in saliva and blood

RUDN University doctors examined markers of liver cancer and found that the disease can be recognized by RNA fragments in saliva and blood. The results are published in Oncotarget.

23 Nov 2021

New score developed to predict outcome in liver cancer patients receiving immunotherapy

There are still no established biomarkers to predict the success of immunotherapy in patients with liver cancer.

22 Nov 2021

Bariatric surgery lowers risk of liver disease, heart complications in patients with fatty liver disease

A Cleveland Clinic study shows that patients with obesity and advanced fatty liver disease who had bariatric weight loss surgery significantly lowered their future risk of liver disease complications and serious cardiovascular disease compared with patients who did not have surgery.

11 Nov 2021

Researchers uncover new genetic link to non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases. It is often associated with obesity and diabetes and is considered a manifestation of metabolic syndrome.

10 Nov 2021

Cancer drugs could be repurposed as potential therapies for Alzheimer's disease

Existing and emerging cancer drugs could be repurposed as therapies to be tested in clinical trials for people at genetic risk of Alzheimer's disease, according to a new study published in Science Advances.

10 Nov 2021

Targeting Shp2 in oncological treatments appears to worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

9 Nov 2021

Study focuses on the high hepatitis C rates in pregnant people

Hepatitis C virus (HCV) infection can lead to long-term health problems including liver damage, liver failure, cirrhosis, liver cancer and even death. These outcomes are especially dangerous for pregnant people and their babies.

29 Oct 2021

UQ start-up secures $1.3 million seed investment to develop new treatment for liver disease

A University of Queensland start-up company, developing a potential new treatment for obesity-related liver disease, has secured a seed investment of $1.3 million from IP Group, a UK-based intellectual property business.

19 Oct 2021

Study identifies DNA mutations linking liver disease with obesity and diabetes

For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease.

13 Oct 2021

6 months to live or die: How long should an alcoholic liver disease patient wait for a transplant?

The night before Brian Gorzney planned to check into rehab for alcohol use, he began vomiting blood. First at 2 a.m. Then 5. And again at 11.

12 Oct 2021

Exosomal and non-exosomal miRNAs may serve as biomarkers for HCV-related cirrhosis, liver cancer

Oncotarget published "Exosomal and non-exosomal miRNA expression levels in patients with HCV-related cirrhosis and liver cancer" which reported that patients with HCV-related cirrhosis are at risk for liver cancer development.

11 Oct 2021

Novel strategy for in vitro cell-selective protection has potential for use in adoptive cell therapy

Adoptive cell therapy (ACT) is an emerging powerful cancerimmunotherapy, which includes a complex process of genetic modification, stimulation and expansion. During invitroorexvivomanipulation, sensitive cells are inescapably subjected to harmful external stimuli. Although a variety ofcytoprotectionstrategies have been developed, their application on ACT remains challenging.

29 Sep 2021

Combination of two drugs may help pancreatic and liver cancer patients

A drug candidate discovered and developed decades ago in the laboratory of UC Davis distinguished professor Bruce Hammock may help control the body's raging and often deadly inflammatory response to chemotherapy treatments, especially for pancreatic and liver cancer patients.

29 Sep 2021

Peter Adams and Gerald Shadel receive NIH grant to explore the link between aging and liver cancer

Sanford Burnham Prebys professor Peter D. Adams, Ph.D., who directs the Aging, Cancer and Immuno-oncology Program and Salk Institute professor Gerald Shadel, Ph.D., who directs the San Diego Nathan Shock Center of Excellence in the Basic Biology of Aging, have been awarded a grant from the NIH's National Institute on Aging for $13 million, funding a five-year project to explore the connection between aging and liver cancer.

24 Sep 2021

Doubling excise duties could prevent alcohol-attributable cancers

In a recent modeling study, scientists at Technische Universität Dresden have examined the impact of increasing taxes on alcoholic beverages on alcohol-attributable cancers in the World Health Organization (WHO) European Region.

22 Sep 2021

Hispanic Americans have a higher risk of preventable infection-related cancers, report shows

A new report shows that although Hispanic men and women in the continental United States and Hawaii have 25% to 30% lower overall cancer incidence and mortality than non-Hispanic Whites, they continue to have a higher risk of potentially preventable, infection-related cancers, including approximately two-fold higher rates of liver and stomach cancers.

21 Sep 2021

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Researchers at the University of Liverpool have shown how SARS-CoV-2 viral proteases attack the host cell, and how this can be targeted to stop virus replication in cell culture using existing drugs.

21 Sep 2021

Two proteins work in tandem to build lifelines to cancer cells, study finds

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

20 Sep 2021

Novel assay helps identify factors that can convert normal cells into liver cancer cells

Researchers at the University of Helsinki could show for the first time that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients.

7 Sep 2021

Prognostic impact of common type of liver cancer depends on tumor size, research reveals

Researchers at the Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine have shown that the prognostic impact of hepatocellular carcinoma (HCC), the most common type of liver cancer, is dependent on tumor size.

6 Sep 2021