Liver Transplant News and Research

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When a patient presents with end stage liver disease or liver failure he or she may be considered for a liver transplantation. The first step in this is often a rigorous assessment and being placed on a waiting list.

Medical center leaders celebrate BRTI's 25th anniversary

Considered a highly risky and controversial medical procedure only 25 years ago, solid organ transplantation is now a life-saving mainstream operation thanks to the extraordinary men and women who gathered at the Winspear Opera House in Dallas on Nov. 11.

24 Nov 2009

Treatment rates for hepatitis C virus declining, say researchers

Researchers from the University of Michigan determined that only 663,000 of the approximately 3.9 million Americans with hepatitis C virus (HCV) infection received antiviral therapy between 2002 and 2007.

24 Nov 2009

Antiviral therapy for hepatitis C appears to be declining in the U.S.; lack of diagnosis is primary barrier to treatment

23 Nov 2009

New hope for patients with liver cancer

In patients with unresectable (unable to be removed by surgery) liver cancer, an interventional radiology procedure called triple-drug transcatheter arterial chemoemobolization (TACE) followed by a liver transplant may significantly increase a patient's chance of long-term survival, according to a study published in the December issue of the American Journal of Roentgenology.

21 Nov 2009

HealthGrades identifies top-rated hospital organ-transplantation centers

The top-rated hospitals for organ transplantation are being identified for the first time today by HealthGrades, the leading independent healthcare ratings organization. Based on patient outcomes, quality data for each of the 266 hospitals that perform transplants have been made public at www.healthgrades.com to help patients in need of kidney, lung, heart and liver transplants research and choose a transplant center.

19 Nov 2009

EDDA Technology recieves CE Mark for its IQQA-Liver advanced clinical application

EDDA Technology today announced the completion of CE mark for its new release of IQQA®-Liver, an advanced clinical application designed to enhance efficiency and precision in liver imaging evaluation and treatment planning.

13 Nov 2009

Transplantation of human mononuclear cells exerts a deleterious effect in rats with liver cirrhosis

The use of stem cells in regenerative medicine is not always beneficial for human health, it may even be harmful according to a work done by the universities of Granada and León. Scientists have demonstrated that transplantation of human mononuclear cells isolated from umbilical cord blood exerted a deleterious effect in rats with liver cirrhosis.

12 Nov 2009

Covidien contraindicates use of its Optimark gadoversetamide injection

Covidien, a leading global provider of healthcare products, today announced that it will voluntarily contraindicate the use of its Optimark™ gadoversetamide injection, a gadolinium-based contrast agent (GBCA), in magnetic resonance imaging (MRI) procedures involving patients with severe renal impairment.

9 Nov 2009

Methacetin breath test predicts long-term survival in patients with chronic viral hepatitis

A methacetin breath test (MBT) that can be performed quickly and noninvasively has been proven to accurately predict survival in patients with viral hepatitis and may be used as an adjunctive tool to MELD.

2 Nov 2009

Interim data from Bristol-Myers Squibb's BARACLUDE study for chronic hepatitis B patients

Bristol-Myers Squibb today announced 48-week data from an ongoing study (ETV-048) of chronic hepatitis B patients with decompensated cirrhosis, in which BARACLUDE demonstrated greater viral suppression compared to adefovir. The new BARACLUDE data were presented today at the 60th Annual Meeting of the American Association for the Study of Liver Diseases.

2 Nov 2009

Extending hepatitis C treatment for liver transplant patients results in sustained viral clearance

Extending hepatitis C treatment for liver transplant patients beyond current practice results in high rates of clearance of the hepatitis C virus from the blood, as well as a low rate of relapse, according to a Henry Ford Hospital study.

2 Nov 2009

HCV progresses more rapidly after liver transplantation in African-Americans compared to whites

Previous studies have shown that hepatitis C virus (HCV) progresses slower prior to liver transplantation in African Americans than in whites. However, researchers demonstrate in this study, which will be presented at the annual meeting of the American Association for the Study of Liver Diseases, that the opposite is true after transplantation, in that recurrent HCV in the transplanted liver progresses faster in African Americans than in whites.

1 Nov 2009

Left side grafting has lower risk to donors; small graft size not the only cause of 'small-for-size graft syndrome'

A recent study by doctors at Shinshu University, School of Medicine, in Japan determined that left side grafting has lower risk to donors compared to grafts taken from the right lobe, and it appears to be the procedure of choice for adult-to-adult living donor liver transplantation (LDLT).

30 Oct 2009

Women face higher risk of graft loss after liver transplantation compared to men

Although women with chronic hepatitis C virus (HCV) infection are at lower risk for developing cirrhosis, researchers who compared outcomes for men and women after having liver transplantation found that women have a significantly increased risk of overall graft loss and graft loss from recurrent HCV than men.

30 Oct 2009

Multidisciplinary center to be launched for treatment of advanced liver disease

Distinguished transplant and cancer surgeon, Alan Hemming, MD, has been recruited to the University of California, School of Medicine to launch a multidisciplinary center for the treatment of advanced liver disease at the UC San Diego Medical Center and Moores UCSD Cancer Center.

28 Oct 2009

Positive results from Phase II clinical trial of INT-747 announced

Intercept Pharmaceuticals, Inc., today announced positive results from a 165 patient, placebo controlled, double-blind Phase II clinical trial of INT-747 in patients with primary biliary cirrhosis (PBC).

27 Oct 2009

UF scientists shed new light on old medical procedure

You might not know what it's called, but if you've had general anesthesia before surgery, especially after an accident, it is likely you have received Sellick's maneuver. That's when fingers are pressed against a patient's throat to prevent regurgitation and spilling of stomach contents into the airway and lungs while anesthesia is being administered.

21 Oct 2009

Patients with chronic hepatitis C can benefit by drinking coffee

Patients with chronic hepatitis C and advanced liver disease who drink three or more cups of coffee per day have a 53% lower risk of liver disease progression than non-coffee drinkers according to a new study led by Neal Freedman, Ph.D., MPH, from the National Cancer Institute (NCI).

20 Oct 2009

Research study reveals SFSGD in EGD individuals with GRBWR below 0.8%

Small-for-size graft dysfunction (SFSGD) following living-related liver transplantation (LRLT) is characterized by early graft dysfunction (EGD) when the graft-to-recipient body weight ratio (GRBWR) is below 0.8%.

19 Oct 2009

Patients sue insurers for denying transplants

The Los Angeles Times has a two-part series on patients who have sued their insurers for denying potentially life-saving transplants.

9 Oct 2009

Liver Transplant News and Research

Further Reading

Medical center leaders celebrate BRTI's 25th anniversary

Treatment rates for hepatitis C virus declining, say researchers

Antiviral therapy for hepatitis C appears to be declining in the U.S.; lack of diagnosis is primary barrier to treatment

New hope for patients with liver cancer

HealthGrades identifies top-rated hospital organ-transplantation centers

EDDA Technology recieves CE Mark for its IQQA-Liver advanced clinical application

Transplantation of human mononuclear cells exerts a deleterious effect in rats with liver cirrhosis

Covidien contraindicates use of its Optimark gadoversetamide injection

Methacetin breath test predicts long-term survival in patients with chronic viral hepatitis

Interim data from Bristol-Myers Squibb's BARACLUDE study for chronic hepatitis B patients

Extending hepatitis C treatment for liver transplant patients results in sustained viral clearance

HCV progresses more rapidly after liver transplantation in African-Americans compared to whites

Left side grafting has lower risk to donors; small graft size not the only cause of 'small-for-size graft syndrome'

Women face higher risk of graft loss after liver transplantation compared to men

Multidisciplinary center to be launched for treatment of advanced liver disease

Positive results from Phase II clinical trial of INT-747 announced

UF scientists shed new light on old medical procedure

Patients with chronic hepatitis C can benefit by drinking coffee

Research study reveals SFSGD in EGD individuals with GRBWR below 0.8%

Patients sue insurers for denying transplants

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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