Living Cells News and Research

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Discovery of method for clamping down on a cancer-promoting enzyme

There are many pathways that allow an errant gene to turn a cell cancerous, and a number of these pathways go through a single enzyme called the p21-activated kinase 1, or PAK1.

18 Apr 2008

TOR signaling and dietary restriction

University of Washington scientists have uncovered details about the mechanisms through which dietary restriction slows the aging process.

17 Apr 2008

Researchers discover protein leiomodin promotes the assembly of an important heart muscle protein actin

Researchers at the University of Pennsylvania School of Medicine have discovered that a protein called leiomodin (Lmod) promotes the assembly of an important heart muscle protein called actin.

11 Apr 2008

Enzyme complex could be key to new cancer treatments

Penn State scientists are the first to observe in living cells a key step in the creation of adenine and guanine, two of the four building blocks that comprise DNA.

4 Apr 2008

Powerful new cell research tool

The view into the inner world of living cells just got a little brighter and more colorful.

26 Feb 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

7 Feb 2008

Scientists create fluorescent proteins for live cell imaging, biosensor design

Scientists at Carnegie Mellon University's Molecular Biosensor and Imaging Center have developed new "fluorogen activating proteins" (FAPs) that will become a key component of novel molecular biosensor technology being created at Carnegie Mellon.

7 Feb 2008

Chemical chaperone could open door to treatment of neurological disorder

An unexpected finding turned out to be a clue leading researchers at Washington University School of Medicine in St. Louis to propose a new treatment approach for Niemann-Pick disease, a rare, deadly neurodegenerative disorder.

7 Feb 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

5 Feb 2008

New understanding on the mechanics of gene transcription

The molecular machinery behind gene transcription -- the intricate transfer of information from a segment of DNA to a corresponding strand of messenger RNA -- isn't stationed in special "transcription factories" within a cell nucleus, according to Cornell researchers.

9 Jan 2008

Model developed that predicts molecular response of living cells to genetic or environmental change

Scientists at the Institute for Systems Biology (ISB), in collaboration with researchers from New York University (NYU), have developed a model which rapidly characterizes and accurately predicts the molecular-level, mechanistic response of a free-living cell to genetic and environmental changes.

28 Dec 2007

How molecular muscles help cells divide

Time-lapse videos and computer simulations provide the first concrete molecular explanation of how a cell flexes tiny muscle-like structures to pinch itself into two daughter cells at the end of each cell division, according to a report in Science Express.

17 Dec 2007

Protein fingerprinting made easy

Combining some traditional experimental methods of molecular biology with computational methods of artificial intelligence, a group of researchers from Ruder Boskovic Instititute and Faculty of Natural Sciences and Mathematics from Zagreb, Croatia, demonstrated a novel approach for producing 'protein fingerprints' of diverse tissues.

13 Dec 2007

Odyssey Thera granted U.S. patent for animal imaging

Odyssey Thera, Inc. has announced that the United States Patent and Trademark Office granted U.S. Patent No. 7,306,914, entitled "Protein-fragment Complementation Assays (PCA) in whole animals: applications to drug efficacy, ADME, cancer biology, immunology, infectious disease and gene therapy.

13 Dec 2007

Scientists levitate cells with light to sort

Separating out particular kinds of cells from a sample could become faster, cheaper and easier thanks to a new system developed by MIT researchers that involves levitating the cells with light.

10 Dec 2007

Bacteria shed light on an important group of human proteins

A collaboration between researchers in Switzerland, the UK and France has led to the solution of the first crystal structure of a member of the Rhesus protein family and thereby shed new light on a group of proteins of great importance in human transfusion medicine.

19 Nov 2007

University of Delaware research to shed light on osteoporosis

Ten million people in the United States are estimated to already have bone diseases, and almost 34 million more are estimated to have low bone mass, putting them at increased risk for osteoporosis, according to the National Osteoporosis Foundation.

16 Nov 2007

New drug may restore memory with Alzheimer's disease

A 2006 study by MetLife found that adults over age 55 fear Alzheimer's disease more than cancer, and with good reason. Alzheimer's creeps up on patients and their families, robbing more than half of all Americans over age 85 of their memory and ability to care for themselves.

14 Nov 2007

Research looks at how environment inside a living cell affects protein structure

The syrupy soup of proteins, ribosomes and membranes inside a living cell is so tightly packed it may increase the structural content of proteins by as much as 25 percent, according to new research from Rice University and the University of Houston (UH).

13 Nov 2007

Tiny fluorescent probes illuminate protein interactions in living cells

While fluorescence has long been used to tag biological molecules, a new technology developed at Yale allows researchers to use tiny fluorescent probes to rapidly detect and identify protein interactions within living cells while avoiding the biological disruption of existing methods, according to a report in Nature Chemical Biology.

13 Nov 2007

Living Cells News and Research

Discovery of method for clamping down on a cancer-promoting enzyme

TOR signaling and dietary restriction

Researchers discover protein leiomodin promotes the assembly of an important heart muscle protein actin

Enzyme complex could be key to new cancer treatments

Powerful new cell research tool

Disrupted genetic regulation causes common disturbance in metabolism of fat

Scientists create fluorescent proteins for live cell imaging, biosensor design

Chemical chaperone could open door to treatment of neurological disorder

Disrupted genetic regulation causes common disturbance in metabolism of fat

New understanding on the mechanics of gene transcription

Model developed that predicts molecular response of living cells to genetic or environmental change

How molecular muscles help cells divide

Protein fingerprinting made easy

Odyssey Thera granted U.S. patent for animal imaging

Scientists levitate cells with light to sort

Bacteria shed light on an important group of human proteins

University of Delaware research to shed light on osteoporosis

New drug may restore memory with Alzheimer's disease

Research looks at how environment inside a living cell affects protein structure

Tiny fluorescent probes illuminate protein interactions in living cells

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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