Low Density Lipoprotein (LDL) News and Research

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New study aims to help clear up conflicting dietary advice around egg consumption

University of Sydney researchers aim to help clear up conflicting dietary advice around egg consumption, as a new study finds eating up to 12 eggs per week for a year did not increase cardiovascular risk factors in people with pre-diabetes and type 2 diabetes.

7 May 2018

Researchers find unexpected anti-inflammatory effects in PCSK9 inhibitors

PCSK9 inhibition is a new therapeutic strategy for atherosclerosis which is known to lower LDL cholesterol.

5 Apr 2018

People with family history of heart attack may be more at risk

The president of the American Heart Association, Dr John Warner, had a minor heart attack recently during a scientific conference held in California.

12 Jan 2018

Study opens up new avenues for stopping calcific aortic valve disease

The diminutive size of our aortic valve -- just shy of a quarter -- belies its essential role in pushing oxygen-rich blood from the heart into the aorta, our body's largest vessel, and from there to all other organs. Yet for decades, researchers have focused less on damaged valves than on atherosclerosis, the gradual hardening of the blood vessels themselves.

26 Dec 2017

FDA statement revokes claims that soy protein reduces heart disease risk

Yesterday (30th October 2017), Susan Mayne,Ph.D. and director of the FDA’s Center for Food Safety and Applied Nutrition, issued a statement on behalf of the United States Food and Drug Administration (FDA) stating that the claims made by earlier studies that soy protein can reduce the risk of heart disease is not true.

30 Oct 2017

Study: Less than half of patients receive insurer's approval for prescription of cholesterol drugs

Less than half of patients received their insurer's approval for prescriptions of PCSK9 inhibitors, according to new research in the American Heart Association's journal Circulation.

30 Oct 2017

Nutrition scientists investigate impact of dietary fats on metabolically healthy obese adults

Metabolically healthy obese adults consuming a diet high in unsaturated fat and low in saturated fat may be able to decrease their total cholesterol by 10 points, a new study suggests.

30 Aug 2017

First-in-class investigational drug lowers LDL cholesterol for up to one year, study finds

Inclisiran lowers low-density lipoprotein (LDL; "bad") cholesterol for up to one year in patients with high cardiovascular risk and elevated LDL cholesterol, according to late-breaking results from the ORION 1 trial presented today in a Hot Line LBCT Session at ESC Congress.

29 Aug 2017

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

The benefit of lowering low-density lipoprotein (LDL) cholesterol depends on how it is lowered, according to late-breaking results from a naturally randomised genetic trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in JAMA.

29 Aug 2017

Women more often receive inadequate treatment to prevent cardiovascular events

Women at high risk of cardiovascular events are less likely to receive recommended statin doses for secondary prevention, according to results from the DYSIS study presented today at ESC Congress.

26 Aug 2017

Child-oriented nutritional intervention contributes advantageously to parents’ diets

Nutrition advice aimed at children also improves parents' diets, according to research published today in the European Journal of Preventive Cardiology.

20 Jul 2017

Study reveals link between cardiovascular risk factors and arterial distensibility in adolescence

The longitudinal study on children and adolescents conducted by the Research Centre of Applied and Preventive Cardiovascular Medicine at the University of Turku, Finland, is unique worldwide.

30 Jun 2017

Study finds vaccine to lower cholesterol levels could also immunize against heart disease

In people with high cholesterol levels, the fat that is built up in the artery walls narrows the arteries causing a condition called atherosclerosis. A study published on 19th June in the European Heart Journal has found the likelihood of a vaccine that can immunize humans having atherosclerosis, subsequent to successful outcomes in a mouse model study. At present, phase I clinical trial has begun in patients to see the possibility of translating the study findings to humans.

20 Jun 2017

Coconut oil in diet is rich in saturated fats and bad for heart says AHA advisory report

According to a new report from the American Heart Association, the use of coconut oil in the diet may not be such a good idea as previously thought.

19 Jun 2017

Vitamin D deficiency linked to early markers of cardiovascular disease in overweight, obese children

In overweight and obese children and adolescents, vitamin D deficiency is associated with early markers of cardiovascular disease, a new study reports. The research results will be presented Sunday, April 2, at ENDO 2017, the annual scientific meeting of the Endocrine Society, in Orlando.

4 Apr 2017

Higher nut intake may help reduce risk of CVD, total cancer and all-cause mortality

In a systematic review and dose-response meta-analysis of prospective studies published in BMC Medicine, researchers looked at the association of nut consumption and risk of cardiovascular disease (CVD), total cancer, and all-cause and cause-specific mortality in adults.

29 Mar 2017

New gene-silencing drugs cut cholesterol levels by half in early research

The first in a new class of gene-silencing drugs, known as inclisiran, has been shown to halve cholesterol levels in patients at risk of cardiovascular disease.

21 Mar 2017

High levels of two biomarkers can predict risk for adverse cardiac events, research suggests

New research suggests that GlycA, a newly identified blood marker, and C-reactive protein both independently predict major adverse cardiac events, including heart failure and death. Patients who have high levels of both biomarkers are at especially high risk.

17 Mar 2017

New class of cholesterol-lowering drug alongside statins can reduce risk of cardiovascular diseases

A new class of cholesterol-lowering drug has been found to help patients cut their risk of cardiovascular disease, stroke and heart attack.