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Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

The study reveals that Novavax's updated XBB.1.5 vaccine effectively induces cross-neutralizing antibodies against multiple Omicron XBB sub-variants in both mice and non-human primates.

5 Sep 2023

Study explores the biology of post-COVID-19 cognitive deficits

Researchers explored the biology of cognitive deficits following acute COVID-19.

4 Sep 2023

Gene variant protects against Alzheimer's and Parkinson's diseases

About one in every five people carries a version of a gene that, although largely unsung, appears to confer protection against both Alzheimer's disease and Parkinson's disease, Stanford Medicine investigators and their colleagues have learned.

30 Aug 2023

Study finds evidence of SARS-CoV-2 exposure in many patients with postviral syndrome

Researchers investigated immunologic and clinical findings indicative of SARS-CoV-2 exposure among individuals with postviral syndrome.

29 Aug 2023

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Researchers investigated whether anti‑interleukin 6 monoclonal antibodies were related to heterogenous treatment effects between male and female COVID-19 patients.

24 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

The gut microbiome of critically ill individuals and its modification by immunonutrition and probiotics

Gut dysbiosis among critically ill individuals

16 Aug 2023

CT imaging reveals that COVID-19 vaccination may protect against severe lung pathology

Researchers determine how COVID-19 vaccination influences lung-sequelae-related pathology and the manifestation of severe infection.

9 Aug 2023

The immune-modulatory effect of lenvatinib investigated in new study

Researchers explore the effect of lenvatinib treatment on patients with advanced thyroid cancer.

9 Aug 2023

Outcome markers in COPD patients with COVID-19

Researchers identify potential markers for severe COVID-19 and death in COPD patients.

8 Aug 2023

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

Researchers describe the virological range of persistent SARS-CoV-2 infection in immunosuppressed individuals.

7 Aug 2023

The immunomodulatory and antiviral function of vitamin D

Vitamin D's immunomodulatory and antiviral function.

4 Aug 2023

Study assesses the value of predictive biomarkers for early-stage COVID-19 infection

Researchers illustrated that certain biomarkers may be better predictors of COVID-19 than others.

2 Aug 2023

Does the anti-influenza vaccination protect against SARS-CoV-2 infection?

Researchers performed a meta-analysis to evaluate the effect of influenza vaccination on SARS-CoV-2 infection.

2 Aug 2023

Revolutionizing COVID-19 ARDS prediction: a deep learning model for critically ill patients

Researchers developed and evaluated a deep learning model for predicting coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS).

31 Jul 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Study offers a comprehensive analysis of bacterial and fungal alterations in COVID-19

Researchers use nanopore sequencing to determine the fungal and bacterial microbiota in the lungs of COVID-19 and non-COVID-19 patients.

24 Jul 2023

The immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species

Researchers characterized the immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species.

19 Jul 2023

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

In a recent study published in Science Translational Medicine, researchers profile antigen-specific helper clusters of differentiation 4-positive (CD4+) T-lymphocytes to determine anti-islet autoimmunity among mice and humans.

9 Jul 2023

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Research discusses the process of discovering anti-inflammatory and neuroprotective drugs from medicinal plants found in the Australian rainforest. It focuses on the pathways from the discovery of bioactive plants to the validation in an appropriate neuro-inflammatory mouse model, using some examples from their current research.