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Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Study: PVC-floored homes are source of phthalate uptake in pregnant women

A new study in the SELMA project at Karlstad University, Sweden, shows that plastic flooring in the home are a source of uptake of phthalates in pregnant women, phthalates that are considered dangerous in the EU chemical regulation system.

27 Sep 2018

New approach promises to forecast cultivar resistance at much earlier stage

Bacterial wilt devastates food crops all over the world. It destroys major crop plants such as tomatoes, potatoes, bananas, ginger and pepper. It occurs in many countries and attacks over 200 plant species.

27 Sep 2018

Exploring parallels between biological and computing world

RNA-based algorithms can advance cellular computing and enable new biological solutions for healthcare and industrial biotechnology.

26 Sep 2018

Harmful H. pylori may play a role in Parkinson's disease

While human genetic mutations are involved in a small number of Parkinson's disease (PD) cases, the vast majority of cases are of unknown environmental causes, prompting enormous interest in identifying environmental risk factors involved.

25 Sep 2018

Recent study helps predict probability of pregnant mothers to have child with autism

Researchers at Rensselaer Polytechnic Institute--led by Juergen Hahn, professor and head of biomedical engineering--are continuing to make remarkable progress with their research focused on autism spectrum disorder.

24 Sep 2018

Study: CXCL14 protein is secreted by brown adipose tissue and has beneficial effects in metabolic diseases

A scientific team found that the CXCL14 protein, associated with tumor progression and organogenesis, causes beneficial effects to metabolic diseases such as obesity and diabetes.

19 Sep 2018

Chinese and German researchers to cooperate more closely in future for better food

Working together for better food: Chinese and German researchers want to cooperate more closely in the future.

18 Sep 2018

Autism biomarker may aid early diagnoses

A newly discovered group of blood metabolites could act as a biomarker to accelerate the diagnosis of autism spectrum disorder.

6 Sep 2018

Metabolic signatures in blood may help in earlier diagnosis of autism, shows research

Metabolic signatures in the blood of children with autism spectrum disorder may lead to earlier diagnosis of the condition for some children, according to newly published research. These biochemical signatures provide insight into how the body metabolizes certain amino acids important to typical neurodevelopment.

6 Sep 2018

Investigators identify group of blood metabolites that could help detect autism

Investigators at the UC Davis MIND Institute and NeuroPointDX, a division of Stemina Biomarker Discovery, have identified a group of blood metabolites that could help detect some children with autism spectrum disorder

6 Sep 2018

Researchers make discovery about yeast metabolism that could help drug developers

Researchers at the Francis Crick Institute have developed machine learning algorithms that can predict the metabolism of yeast based on its protein content.

6 Sep 2018

Abnormal levels of metabolites can reliably predict lung disease in 9/11 firefighters

Abnormal levels of more than two dozen metabolites -; chemicals produced in the body as it breaks down fats, proteins and carbohydrates -; can reliably predict which Sept. 11 firefighters developed lung disease and which did not, a new analysis shows.

4 Sep 2018

Hesperos receives SBIR grant to create ‘human-on-a-chip’ model to mimic Alzheimer's disease

Hesperos, Inc., announced today the receipt of a NIH Phase I Small Business Innovation Research grant from the National Institutes of Health National Institute on Aging to help create a new multi-organ "human-on-a-chip" model that can realistically mimic the biology of Alzheimer's Disease and the effects of potential new therapies under realistic human physiological conditions.

29 Aug 2018

Widely-used artificial sweetener produces previously unidentified metabolites, study finds

Sucralose, a widely used artificial sweetener sold under the trade name Splenda®, is metabolized in the gut, producing at least two fat-soluble compounds, according to a recent study using rats.

27 Aug 2018

Fresh and raw diets may provide benefits for dogs, study finds

Many dog owners think of their furry companions as part of the family, and now products are available to feed them that way, too.

24 Aug 2018

Study uncovers link between gut bacteria and 'hedonic eating'

A study of 63 healthy people showed that those with elevated microbiome levels of the metabolite indole -; produced when gut bacteria break down the amino acid tryptophan -; had stronger function and connectivity in specific areas of the brain's reward network.

24 Aug 2018

Sleep loss can confer increased risk of adverse weight gain, shows study

In a new study, researchers at Uppsala University now demonstrate that one night of sleep loss has a tissue-specific impact on the regulation of gene expression and metabolism in humans.

23 Aug 2018

Study may fuel need for effective drug testing in hospital emergency departments

At a time when drug overdoses are becoming more prevalent and lethal, a new report provides a snapshot of regional illicit drug use and, for the first time, highlights the complexity of detecting and treating patients at hospital emergency departments for a severe drug-related event.

21 Aug 2018

Study uncover metabolic network controlled by the ‘circadian clock’ of muscle cells

How do muscle cells prepare for the particular metabolic challenges of the day? Scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München, members of the German Center for Diabetes Research, have investigated this question and published their results in 'PLOS Biology'.

21 Aug 2018

Metabolites News and Research

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Study: PVC-floored homes are source of phthalate uptake in pregnant women

New approach promises to forecast cultivar resistance at much earlier stage

Exploring parallels between biological and computing world

Harmful H. pylori may play a role in Parkinson's disease

Recent study helps predict probability of pregnant mothers to have child with autism

Study: CXCL14 protein is secreted by brown adipose tissue and has beneficial effects in metabolic diseases

Chinese and German researchers to cooperate more closely in future for better food

Autism biomarker may aid early diagnoses

Metabolic signatures in blood may help in earlier diagnosis of autism, shows research

Investigators identify group of blood metabolites that could help detect autism

Researchers make discovery about yeast metabolism that could help drug developers

Abnormal levels of metabolites can reliably predict lung disease in 9/11 firefighters

Hesperos receives SBIR grant to create ‘human-on-a-chip’ model to mimic Alzheimer's disease

Widely-used artificial sweetener produces previously unidentified metabolites, study finds

Fresh and raw diets may provide benefits for dogs, study finds

Study uncovers link between gut bacteria and 'hedonic eating'

Sleep loss can confer increased risk of adverse weight gain, shows study

Study may fuel need for effective drug testing in hospital emergency departments

Study uncover metabolic network controlled by the ‘circadian clock’ of muscle cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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