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Study on how immune systems of astronauts respond to seasonal flu vaccine

Every year, as influenza season - and flu shot season--rolls around, medical experts weigh in on just how effective it will be against that year's particular strain. What if that equation could take into account a person's own immune response?

24 Dec 2015

Identifying new mechanism for aspirin in cancer prevention

Aspirin has been shown to decrease the risk of colorectal cancer and possibly other cancers. However, the risk of side effects, including in some cases severe gastrointestinal bleeding, makes it necessary to better understand the mechanisms by which aspirin acts at low doses before recommending it more generally as a preventative, says Cornelia Ulrich, PhD, Senior Director of Population Sciences at Huntsman Cancer Institute in Salt Lake City.

19 Nov 2015

Study may lead to development of highly accurate screening test for early-stage ovarian cancer

Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.

17 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

Support comes out of the ground: Scientists from the Helmholtz Centre for Infection Research in Germany have identified a terrestrial myxobacterium as a promising source for the bengamide class of natural products, which were originally thought to be secondary metabolites of marine sponges only.

17 Nov 2015

New computational method helps predict adverse drug reaction better than traditional computing methods

A new integrated computational method helps predicting adverse drug reaction--which are often lethal--more reliably than with traditional computing methods. This improved ability to foresee the possible adverse effects of drugs may entail saving many lives in the future.

4 Nov 2015

Denator forms a new Scientific Advisory Board

Denator AB has announced that a new external expert advisory board has been formed. Karsten Fjärstedt, recently appointed as CEO comments, “It is a great honor for me to be entrusted to lead Denator forward in this new phase of development. With a pipeline of new exciting business opportunities and a strong Scientific Advisory Board (SAB) I am looking forward to realizing the full potential of the company technology”.

3 Nov 2015

Radiocarbon method proves Cameroon’s environment is contaminated with synthetic opioid

Tramadol, a synthetic opioid component of the painkiller tramal, was surprisingly identified in 2013 as a natural product of Sarcocephalus latifolia, a tree found in Cameroon.

31 Oct 2015

Study reports discovery of new class of DNA repair enzyme

This year's Nobel Prize in chemistry was given to three scientists who each focused on one piece of the DNA repair puzzle. Now a new study, reported online Oct. 28 in the journal Nature, reports the discovery of a new class of DNA repair enzyme.

30 Oct 2015

SLU VTEU awarded $5.8 million NIH contract to support 'omics' research initiative

Saint Louis University's Vaccine and Treatment Evaluation Unit has received a five-year, $5.8 million contract from the National Institutes of Health to support an "omics" research initiative to study the safety and effectiveness of vaccines and other ways to fight infectious diseases.

30 Oct 2015

New screening method can detect secondhand marijuana exposure

With increased legalization of marijuana for medicinal and recreational purposes, interest is growing in the potential health effects of its secondhand smoke. A team now reports in ACS' journal Analytical Chemistry the development of a urine screening method that is sensitive enough to detect even small amounts of chemicals that result from this exposure.

29 Oct 2015

New analysis confirms presence of mycotoxins in coffees sold in Spain

An analysis of one hundred coffees sold in Spain has confirmed the presence of mycotoxins -toxic metabolites produced by fungi. In addition, five of the samples that were tested were found to contain ochratoxin A, the only legislated mycotoxin, in amounts that exceeded maximum permitted levels.

29 Oct 2015

Miniaturized microfluidic device can help monitor blood levels in real time for patients in ICU

No larger than a pack of chewing gum, the prototype developed by EPFL's Integrated Systems Laboratory is deceptively simple in appearance. But this little black case with two thin tubes sticking out contains some real miniaturized high-tech wonders.

23 Oct 2015

JDRF-funded study aims to find new types of diagnostic markers for diabetic kidney disease

In an effort to pinpoint the earliest signs of diabetic kidney disease, researchers at University of California, San Diego School of Medicine are leading a multi-institutional international effort dedicated to finding a new breed of disease indicators.

23 Oct 2015

Early Parkinson's diagnosis may be possible using skin odour

A study has been launched to identify small molecules secreted by the skin that are believed to emit a subtle but unique scent in people in the early stages of Parkinson’s.

22 Oct 2015

Different Crohn's disease treatments affect children's gut microbes in distinct ways

Different treatments for Crohn's disease in children affects their gut mi-crobes in distinct ways, which has implications for future development of microbial-targeted therapies for these patients, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Oct 2015

New data analysis platform reveals major flaw in GC-MS process

A new study led by scientists at The Scripps Research Institute (TSRI) shows that a technology used in thousands of laboratories, called gas chromatography mass spectrometry (GC-MS), fundamentally alters the samples it analyzes.

7 Oct 2015

Bioreactor Monitoring using Mass Spectrometry

Chuck DeCarlo provides advice on bioreactor monitoring using mass spectrometry and gives an introduction to the MAX300-BIO bioreactor gas analyzer.

From Extrel CMS, LLC 28 Sep 2015

New study heightens concerns over detrimental impact of air pollution on gene associated with AD risk

A new study by researchers at the Universities of Montana, Valle de México, Boise State, and North Carolina, the Centro de Ciencias de la Atmósfera, Universidad Nacional Autónoma de México, Instituto Nacional de Pediatría, and Centro Médico Cozumel heightens concerns over the detrimental impact of air pollution on hippocampal metabolites as early markers of neurodegeneration in young urbanites carrying an allele 4 of the apolipoprotein E gene (APOE).

26 Sep 2015

Researchers identify new biochemical pathway that could be a potential target for insulin control

In the final event leading to the development of Type 2 diabetes, the pancreas loses its ability to secrete insulin and clear glucose from the blood. Preventing this breakdown in insulin secretion is a key goal in the fight to reduce the burden of a disease that afflicts an estimated 29 million people in the United States.

25 Sep 2015

Metabolites News and Research

Study on how immune systems of astronauts respond to seasonal flu vaccine

Identifying new mechanism for aspirin in cancer prevention

Study may lead to development of highly accurate screening test for early-stage ovarian cancer

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

New computational method helps predict adverse drug reaction better than traditional computing methods

Denator forms a new Scientific Advisory Board

Radiocarbon method proves Cameroon’s environment is contaminated with synthetic opioid

Study reports discovery of new class of DNA repair enzyme

SLU VTEU awarded $5.8 million NIH contract to support 'omics' research initiative

New screening method can detect secondhand marijuana exposure

New analysis confirms presence of mycotoxins in coffees sold in Spain

Miniaturized microfluidic device can help monitor blood levels in real time for patients in ICU

JDRF-funded study aims to find new types of diagnostic markers for diabetic kidney disease

Early Parkinson's diagnosis may be possible using skin odour

Different Crohn's disease treatments affect children's gut microbes in distinct ways

New data analysis platform reveals major flaw in GC-MS process

Bioreactor Monitoring using Mass Spectrometry

New study heightens concerns over detrimental impact of air pollution on gene associated with AD risk

Researchers identify new biochemical pathway that could be a potential target for insulin control

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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