Metformin News and Research

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Metformin is the active ingredient in a drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood). It is also being studied in the treatment of cancer. It decreases the amount of glucose (a type of sugar) released into the bloodstream from the liver and increases the body’s use of the glucose. Metformin is a type of antidiabetic agent.

GSK strongly disagrees with conclusions reached in NEJM article on Avandia

GlaxoSmithKline has issued the following response to an article in the New England Journal of Medicine (NEJM) on Avandia (rosiglitazone maleate), a widely used and highly effective treatment for type 2 diabetes.

22 May 2007

FDA in trouble over widely used diabetic drug Avandia

A diabetes pill which has been widely used since 1999 is now suspected of increasing the risk of heart attacks for those taking it.

22 May 2007

OCT1 required for therapeutic effects of diabetes drug Metformin

The drug metformin is among the most widely prescribed drugs for the treatment of type 2 diabetes and results in an array of therapeutic benefits.

2 May 2007

Mylan announces FDA approval for Glipizide and Metformin Hydrochloride tablets

Mylan Laboratories has announced that Mylan Pharmaceuticals Inc. has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Glipizide and Metformin Hydrochloride Tablets in 2.5 mg/250 mg, 2.5 mg/500 mg and 5 mg/500 mg strengths.

14 Apr 2007

Growing number of young people have fatty liver disease

Indiana University School of Medicine researchers are taking a closer look at a disease whose incidence is rising as obesity in children increases.

15 Mar 2007

High blood glucose levels may signal an increased risk for cancer in women

The March journal also includes a study that found a link between high levels of persistent organic pollutants (POPs) in a person's bloodstream and insulin resistance, a precursor for type 2 diabetes.

27 Feb 2007

New diabetes drug Januvia works without causing weight gain

The Food and Drug Administration (FDA) in the U.S. has granted approval for a new drug to treat adults with type 2 diabetes.

17 Oct 2006

FDA approves Januvia for diabetes

The Food and Drug Administration (FDA) announced today the approval of Januvia (sitagliptin phosphate) Tablets, the first diabetes treatment approved in a new class of drugs known as DDP-4 inhibitors that enhances the body's own ability to lower elevated blood sugar.

17 Oct 2006

Race affects medication adherence

African Americans may be less likely than whites to take their medication for Type 2 diabetes as it is prescribed, a new study suggests.

2 Aug 2006

Berberine has beneficial effects for people suffering from type 2 diabetes

Reports of a traditional Chinese medicine having beneficial effects for people suffering from type 2 diabetes now has some scientific evidence to back up the claims.

2 Aug 2006

1 in 5 youth with diabetes has heart risk

With the epidemic of obesity in the United States leading to a greater incidence of diabetes among youth, a new study highlights why Americans cannot afford to ignore this dangerous trend: One in five youth with diabetes has already developed two or more additional risk factors for premature heart disease.

27 Jul 2006

Gene variant increases risk of type 2 diabetes - but healthy lifestyle changes reduce genetic risk

Researchers have confirmed that a gene variant confers susceptibility to type 2 diabetes in participants of the Diabetes Prevention Program (DPP), a large clinical trial in adults at increased risk for developing type 2 diabetes.

21 Jul 2006

Impact of obesity on treatment of chronic hepatitis C

According to a new study, obese patients chronically infected with the hepatitis C virus (HCV) and treated with combination drug therapy may have better outcomes if the underlying abnormalities caused by excessive fat tissue are corrected.

6 Jun 2006

Latest diabetic medications more costly, but users have fewer hospital visits

Diabetics who were prescribed newer medications to control their illness were more likely to take these drugs as instructed than were other patients who were prescribed drugs that have been on the market for several decades.

22 Mar 2006

Weight loss and exercise reduces urinary incontinence in women with prediabetes

Losing a modest amount of weight through dietary changes and increased physical activity reduces the occurrence of urinary incontinence (UI) in women with prediabetes, a condition in which blood glucose levels are higher than normal but not yet diabetic.

27 Jan 2006

$More fractures, less bone density in premenopausal women with diabetes$

More fractures, less bone density in premenopausal women with diabetes

Premenopausal women who have type 1 diabetes should strongly consider preventive screening for osteoporosis, the researchers of a new study on bone density conclude in the February issue of Diabetes Care.

27 Jan 2006

Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

A study published in The Lancet shows that Takeda's Actos (pioglitazone HCl), an oral glucose lowering medication, significantly reduces the combined risk of non-fatal heart attacks, strokes and deaths by an additional 16% on top of standard medication

10 Oct 2005

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network has launched its second clinical trial to study NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol. The first trial, launched in January of this year, focuses on adults, while the second trial studies the disease in children.

27 Sep 2005

Oral medications may control symptoms of Type II diabetes in children just as well as insulin injections

According to the medical records of 26 children diagnosed with the disease, oral medications reduced levels of a compound in the blood called hemoglobin A1C by an average of 2 percentage points.

15 Aug 2005

Ranbaxy receives tentative approval to manufacture and market Glimepiride tablets

Indian drug manufacturer, Ranbaxy Pharmaceuticals has tentative approval from the U.S. Food and Drug Administration to manufacture and market Glimepiride Tablets, 3 mg and 6 mg.

28 Jul 2005