Microscope News and Research

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Doctors may be over-diagnosing melanoma in sun-damaged skin

A Mayo Clinic physician and colleagues have defined the normal number of melanocytes that are present in Caucasians' sun-exposed skin.

18 Jul 2006

Scientists develop piezoresponse force microscopy

A seminal early event in the history of nanotechnology was the development of the atomic force microscope (AFM), which used a nanoscale cantilever to image solid materials at the atomic level.

17 Jul 2006

Gene screen for breast cancer better than pathologist's "eye"

Johns Hopkins scientists have found that a method they developed to screen body fluids for certain kinds of cells and some of their genetic blueprint is twice as accurate at spotting breast cancer cells as a pathologist's view with a microscope.

17 Jul 2006

A new diagnostic tool for prostate cancer

According to the World Health Organization there are about 250,000 new cases of prostate cancer every year but, when caught in time, the disease has a cure rate of over 90%.

12 Jul 2006

Determining the genetic composition of brain cancers informs treatment, predicts outcome

Research confirms that determining the genetic composition of brain cancers can better inform doctors and patients for treatment options and prognosis.

11 Jul 2006

Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas

Most attempts to develop imaging agents that can better distinguish tumors from healthy tissue focus on finding molecules that are more abundant on malignant cells than on normal cells and using those as cellular targets.

10 Jul 2006

Thermosensitive pluronic micelles stabilized by shell cross-linking with gold nanoparticles

Many types of nanoparticles can cross the cell membrane and deliver their therapeutic payload into tumor cells.

3 Jul 2006

Early marker for autism found in the placenta

A team from Yale School of Medicine have found an abnormality in the placenta which could be the first indication of autism and they believe the discovery could lead to a diagnosis of the condition at birth, rather than the standard age of two or older.

27 Jun 2006

The protein that makes you mad

In recent years our feeding habits have been the focus of ongoing polemics. Everybody will remember the "mad cow" crisis.

26 Jun 2006

Scientists watch the behavior of a single gene in real time

Scientists at the Albert Einstein College of Medicine of Yeshiva University have observed for the first time that gene expression can occur in the form of discrete "pulses" of gene activity.

14 Jun 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

Promising chemo, therapeutic viruses, cutting-edge surgery debut at M. D. Anderson Cancer Center

Brain tumor specialists at The University of Texas M. D. Anderson Cancer Center are poised on the brink of a new era.

10 May 2006

Stem cell 'fusion' occurs in tumors

An Oregon Health & Science University study is adding credence to an increasingly popular theory that fusion is what bonds stem cells with bone marrow cells to regenerate organ tissue.

10 May 2006

Gene silencing protein discovered

A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off -in this case, the turning off of thousands of nearly identical genes in a hybrid plant.

8 May 2006

MicroCT-based virtual histology

Utah and Texas researchers combined miniature medical CT scans with high-tech computer methods to produce detailed three-dimensional images of mouse embryos - an efficient new method to test the safety of medicines and learn how mutant genes cause birth defects or cancer.

8 May 2006

Magnetic nanotechnology holds promise in fighting cancer

Detecting cancer and reinventing computing are two challenges that seemingly have little, if anything, to do with each other. That is, unless you are a nanotechnologist like Shan Wang, an associate professor of materials science and engineering and of electrical engineering at Stanford.

20 Apr 2006

Muscles burn lactic acid as well as carbos

In the lore of marathoners and extreme athletes, lactic acid is poison, a waste product that builds up in the muscles and leads to muscle fatigue, reduced performance and pain.

20 Apr 2006

New design lets mini-microscope observe cells in vivo

Two eyes are better than one. Or more precisely, two lines of sight are better than one. That's the word from researchers at the Stanford School of Medicine, who have applied this adage to the design of a tiny microscope that is about the size of an M&M.

20 Apr 2006

St. Jude develop strategy to speed future development of more effective and less toxic treatments for medulloblastoma

Investigators at St. Jude Children’s Research Hospital have developed a strategy to speed future development of more effective and less toxic treatments for medulloblastoma, a type of brain cancer. Medulloblastomas arise in the back of the brain and account for about 20 percent of childhood brain tumors.

18 Apr 2006

Computer program lets people with Trigeminal neuralgia diagnose themselves

Trigeminal neuralgia, or TN, is a disorder affecting the areas of the face where the trigeminal nerve's branches are distributed, including the lips, eyes, nose, scalp, forehead, and upper and lower jaws.

13 Apr 2006