Monoclonal Antibody News and Research

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Monoclonal antibodies (MAbs) are produced from a single B cell clone and can bind to a single type of antigen binding site. MAbs are homogenous antibodies that cannot form lattices with monomeric proteins as they can bind to only a single epitope on the antigen. Developed in the 1970s, MAbs can be produced against any given substance. Thus they can be used to detect and purify any substance of interest. This has made MAbs a powerful tool of molecular biology, biochemistry, and medicine.
Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

Post-exposure prophylaxis with monoclonal antibodies may reduce health system burden in the US

Post-exposure prophylaxis with monoclonal antibodies may reduce health system burden in the US

Research uncovers test to identify iMCD patients with superior response to FDA-approved treatment

Research uncovers test to identify iMCD patients with superior response to FDA-approved treatment

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

Monoclonal antibody treatment combo can reduce the impact of COVID-19 in high-risk patients

Monoclonal antibody treatment combo can reduce the impact of COVID-19 in high-risk patients

ACTG announces positive data for monoclonal antibody combination therapy from the ACTIV-2 study

ACTG announces positive data for monoclonal antibody combination therapy from the ACTIV-2 study

Persistence of Anti-PF4 levels in VITT patients four months after AstraZeneca COVID-19 vaccine

Persistence of Anti-PF4 levels in VITT patients four months after AstraZeneca COVID-19 vaccine

Hot spots where covid vaccination lags push experimental antibody treatment

Hot spots where covid vaccination lags push experimental antibody treatment

Non-invasive retinal imaging may be useful for detecting Alzheimer's disease risk

Non-invasive retinal imaging may be useful for detecting Alzheimer's disease risk

MHRA approves first monoclonal antibody treatment for COVID-19 in the UK

MHRA approves first monoclonal antibody treatment for COVID-19 in the UK

Data reinforces SAB-185’s potential to neutralize SARS-CoV-2 variants

Data reinforces SAB-185’s potential to neutralize SARS-CoV-2 variants

Camelid nanobody anti-SARS-CoV-2 drug candidates

Camelid nanobody anti-SARS-CoV-2 drug candidates

Small NIH clinical trial shows that new monoclonal antibody can prevent malaria

Small NIH clinical trial shows that new monoclonal antibody can prevent malaria

Study defines SARS-CoV-2 antibodies associated with neutralization and effector functions

Study defines SARS-CoV-2 antibodies associated with neutralization and effector functions

New insight into impact of SARS-CoV-2 mutations on receptor binding

New insight into impact of SARS-CoV-2 mutations on receptor binding

Aducanumab approval for Alzheimer's may provide a proof of concept that can be rapidly improved upon

Aducanumab approval for Alzheimer's may provide a proof of concept that can be rapidly improved upon

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

Monoclonal antibody could inform development of pan-coronavirus vaccines

Monoclonal antibody could inform development of pan-coronavirus vaccines