Musculoskeletal News and Research

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Too many 'sickies' could mean a shorter life

Researchers in Britain say workers who take long spells of sick leave more than once in three years, are at a higher risk of death than their colleagues who take no such absence.

6 Oct 2008

Statin-induced muscle disorders are focus of $2.5 million in grants from NIH

Approximately 200,000 of the 38 million people in the U.S. who take statins to treat high cholesterol may develop life-threatening muscle disease.

2 Oct 2008

Arthritis treatments glucosamine and chondroitin shown to be no better than placebo

According to the latest research, the popular supplements glucosamine and chondroitin sulfate, used to fight arthritis and joint pain, do not seem to work any better than a placebo in slowing the loss of knee cartilage in osteoarthritis.

30 Sep 2008

One million pounds to improve access to physiotherapy

Providing timely access to physiotherapy is a long-standing problem for the NHS, with more than 4 million new referrals each year and waiting times of several months in many areas. A Bristol-led study to improve access has been given £1.06 million by the Medical Research Council (MRC).

15 Sep 2008

Gleevec receives FDA priority review for gastrointestinal stromal tumors after surgery

Novartis has announced that Gleevec (imatinib mesylate) tablets, (known as Glivec (imatinib) outside the US, Canada and Israel), has been granted priority review status by the US Food and Drug Administration (FDA) as the first therapy to be reviewed for use after surgery in kit-positive gastrointestinal stromal tumors (GIST).

27 Aug 2008

Running and regular exercise mean a longer life with fewer disabilities

According to scientists in the U.S. people who keep fit by running when they are middle aged and older, are less likely to become disabled later in life and may live longer.

11 Aug 2008

600,000 Australians afflicted with osteoporosis

According to a new report by the Australian Institute of Health and Welfare (AIHW) and Osteoporosis Australia, more than 600,000 Australians are affected by osteoporosis.

5 Aug 2008

After ankle surgery: mobilise with care

People recover faster after surgery for ankle fracture if they are given a cast or splint that can be removed to let them exercise the ankle, than if their foot is placed in an immobilising plaster cast. If the fracture is stable, then encouraging them to walk soon after surgery is also beneficial.

16 Jul 2008

Resveratrol improves health, but not longevity in aging mice

Scientists have found that the compound resveratrol slows age-related deterioration and functional decline of mice on a standard diet, but does not increase longevity when started at middle age.

3 Jul 2008

Being born over 10 pounds increases risk of developing rheumatoid arthritis

People who have a birthweight over 10 pounds are twice as likely to develop rheumatoid arthritis when they are adults compared to individuals born with an average birthweight, according to a study published by researchers from Hospital for Special Surgery online in advance of print in the Annals of the Rheumatic Diseases. While the mechanism for this association is unclear, the study identifies a potentially modifiable risk factor and highlights a potential way to decrease the incidence of the disease.

30 Jun 2008

Discovery of possible new way to block inflammation in autoimmune disease

Researchers from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), have identified a promising new target for autoimmune disease treatment - a cell-surface receptor called DR3.

23 Jun 2008

Largest ever Canadian study on osteoporosis informs health policy

Dr David Goltzman and his team from the Research Institute of the McGill University Health Centre (RI MUHC) and McGill University - along with colleagues from across Canada - have issued new recommendations to public health authorities about how to best cope with osteoporosis, a bone disease which leads to increased risk of fracture, particularly in the elderly.

16 Jun 2008

Molecular pathway in muscle helps explain effectiveness of diabetes interventions

Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), demonstrate for the first time in a mouse model that skeletal muscle cells cultured in a low-calorie environment refrain from differentiating, an energy-demanding process by which cells mature and specialize.

12 May 2008

A new search for causes of autism

Dr. Eric Fombonne, from the Research Institute of the MUHC at the Montreal Children's Hospital, is involved in a multi-site consortium to gather DNA samples from 2,000 autism patients and their families over the next three years.

7 May 2008

Geron Corporation awarded UK grant funding for human embryonic stem cell research

Geron Corporation announced today two grant awards to the University of Edinburgh from the UK Stem Cell Foundation, with funding from the Medical Research Council and Scottish Enterprise.

6 May 2008

Gastric bypass surgery and effect on lower back pain

The prevalence of both obesity and back pain in developing nations has reached alarming levels. According to recent statistics, more than one-third of U.S. adults - over 72 million people were obese in 2005-2006. Of these, 33.3 percent were men and 35.3 percent were women. Especially alarming is that obesity has not decreased among teenagers - the rates remain essentially unchanged in 2005-2006 from the 2003-2004 estimates, at 17 percent.

29 Apr 2008

Mending tendons without surgery

James McGillicuddy was not getting good news. Three years after arriving at Stanford as one of the nation's top high school football recruits, he'd been stuck on the sidelines the entire time by a torn tendon that, even with two surgeries, just wouldn't stay fixed. More surgery would not help, his doctors told him, but they did have one last option to offer him.

21 Apr 2008