Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

A new study evaluates the repRNA vaccine expressing the SARS-CoV-2 spike protein for the B.1.1.7 and B.1.351 variants in mice and hamsters.

19 Dec 2021

Nanoparticle therapeutic can be a potential new approach for treating malignant pleural effusion

Researchers at Wake Forest School of Medicine have discovered that a nanoparticle therapeutic enhances cancer immunotherapy and is a possible new approach in treating malignant pleural effusion (MPE).

16 Dec 2021

Driving up immunity at tumor site may help enhance immunotherapy treatments

Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

14 Dec 2021

Recycling tubular endosomes are associated with effective delivery of mRNA-based therapeutics, study finds

A recent study recently demonstrates the endosomal transport of nanoparticle-based formulations for the effective delivery of mRNA-based therapeutics.

14 Dec 2021

"Supermere" discovery may offer clues to earlier diagnoses and treatment of several diseases

Researchers at Vanderbilt University Medical Center have discovered a nanoparticle released from cells, called a "supermere," which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer's disease and even COVID-19.

14 Dec 2021

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A recent review in the journal Life provided a detailed description of CRISPR-Cas-based diagnostic techniques to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but also emphasized the potential use of this technology towards developing effective molecular diagnostic platforms for any future pandemic.

13 Dec 2021

CRISPR/Cas9 gene editing enables sonodynamic therapy to effectively shrink tumors

Sonodynamic therapy uses ultrasound in combination with drugs to release harmful reactive oxygen species (ROS) at the site of a tumor.

8 Dec 2021

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

Smart transformable nanoparticles show promise for enhanced tumor theranostics

For more than three decades, biomedical nanomaterials have been successfully developed for the benefit of theranostics -- a compound term referring to the diagnoses and treatment of tumors.

7 Dec 2021

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

In a recent study conducted at Yale University, USA, scientists have investigated the immunogenicity of mRNA-based coronavirus disease 2019 (COVID-19) vaccine candidates encoding the spike proteins of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The findings reveal that the vaccines induce robust immune responses against SARS-CoV-2 variants. The study is currently available on the bioRxiv* preprint server.

6 Dec 2021

New nanoparticle adjuvant could help make vaccines more powerful

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant -; a compound that stimulates the immune system to produce a stronger response.

3 Dec 2021

Plant-derived virus-like particle vaccines against SARS-CoV-2

In a review published in Biotechnology Letters, the authors discuss plant-derived VLP-based vaccines.

1 Dec 2021

Nanoengineers develop a new approach to effectively deliver mRNA into cells

Nanoengineers at the University of California San Diego have developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells.

30 Nov 2021

From tiny particles to big success: Knauer awarded the innovation prize for Berlin Brandenburg

The producer of high-tech laboratory systems, KNAUER Wissenschaftliche Geräte GmbH was awarded the prestigious Innovation Prize for the Berlin Brandenburg region for their new system for the production of lipid nanoparticles (LNPs).

From KNAUER Wissenschaftliche Geräte GmbH 30 Nov 2021

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Scientists generate a VLP type NP platform made of recombinant viral antigens conjugated with TMV virions.

23 Nov 2021

New technology could revolutionize treatment of pediatric burns

Burns are one of the most common injuries suffered by Australians and one of the top causes of death in children under four. While survival rates for burns patients have improved substantially, treating paediatric burns remains challenging, especially with the rise of multi-drug resistant bacteria.

17 Nov 2021