Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

A recent study illustrated the enhanced distinct clustering of pseudotyped particles (PPs) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

12 Apr 2022

UC researcher awarded renewal grant to continue the study of genetic drivers of breast cancer

A grant renewal for a University of Cincinnati researcher will help continue the study of genetic drivers of breast cancer and potential therapeutic targets.

7 Apr 2022

Self-assembling SARS-CoV-2 spike protein-directed nanoparticle vaccines

A new preprint study depicted the generation of self-assembling coronavirus disease 2019 (COVID-19) nanoparticle vaccines.

6 Apr 2022

Mosaic-8 RBD-nanoparticles show promise as a vaccine candidate for SARS-CoV-2 and potential sarbecoviruses spillovers

Researchers designed nanoparticles representing RBDs of the S protein of animal sarbecoviruses and SARS-CoV-2 to evaluate their potential as a pan-sarbecovirus vaccine candidate.

31 Mar 2022

The potential efficacy of nasal nanoparticle COVID-19 vaccines

The current paper reviews progress in this field regarding nasal nanoparticle vaccines for COVID-19.

30 Mar 2022

A ferritin nanoparticle candidate vaccine for COVID

In a recent study published on the bioRxiv* preprint server, the immunogenicity, and effectiveness of SARS-CoV-2 spike ferritin nanoparticle (SpFN) adjuvanted with aluminum hydroxide (AlOH3) or Army Liposomal Formulation QS-21 (ALFQ) in a cynomolgus macaque (CM) COVID-19 model was evaluated.

30 Mar 2022

Researchers use optoacoustics for high-precision neuromodulation

Neuromodulation plays an important role in deciphering neural circuits and exploring clinical treatment of neurological diseases.

28 Mar 2022

A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers

A team of international scientists has developed an mRNA-based coronavirus disease 2019 (COVID-19) vaccine encoding the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant. The vaccine candidate has shown high efficacy in inducing neutralizing antibodies and protecting against delta infection in mice. The study is currently available on the bioRxiv* preprint server.

24 Mar 2022

New nanoparticle-based COVID-19 vaccine platform could target other infectious diseases

Just one dose of a new nanoparticle-based COVID-19 vaccine was enough to produce an immune response in animals on track with vaccines currently in clinical use.

23 Mar 2022

Study discovers potent and selective human monoclonal antibodies against Omicron variant of SARS-CoV-2

In a new study, researchers discovered human monoclonal antibodies, which were specific and potent against the severe acute respiratory syndrome coronavirus 2 Omicron variant.

23 Mar 2022

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

Researchers report the results for a new SARS-CoV-2 vaccine currently in Phase III clinical trial known as I53-50.

22 Mar 2022

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Researchers analyzed the innate and adaptive responses to the mRNA-based BNT162b2 COVID-19 vaccine in mice.

18 Mar 2022

Nanoparticle-enhanced phototherapies for cancer treatment

Treating cancer and other diseases with laser light is not currently considered routine in the clinical setting, but new approaches using nanoparticles show some promise in improving existing techniques.

15 Mar 2022

New way to deliver potential HIV vaccine using mRNA technology

Using mRNA technology like that in the COVID-19 vaccines, researchers have demonstrated a successful way to deliver a potential HIV vaccine, researchers at Duke Human Vaccine Institute report.

15 Mar 2022

Antimicrobial prescribing among infants may be prevented using maternal RSV vaccines

RSV is a leading cause of severe acute lower respiratory tract infections (LRTIs) among infants globally, and a prominent contributor to common non-severe infections that account for high volumes of antibiotic consumption.

14 Mar 2022

New approach to send ‘friendly’ nano-particles into the body shows promising results

A new approach to send ‘friendly’ nano-particles into a patient’s blood stream has shown promising results by modifying the surface of these potential drug, vaccine or cancer treatment delivery objects to encourage the best result.

14 Mar 2022

Lower, more frequent doses of nanomedicines may provide additional benefits for cancer patients

Tiny structures called nanoparticles can be used to carry substances to certain parts of the body-;for example, to deliver a chemotherapy drug to a tumor.

11 Mar 2022

Study indicates a 100 µg mRNA-1273 booster has acceptable safety and robust antibody response against SARS-CoV-2

A recent study assessed the safety and immunogenicity of mRNA-1273 booster vaccine against COVID-19.

11 Mar 2022

Using metal oxide nanoparticles as 'radiosensitizers' for gentler cancer treatment

Radiation therapy is one of the cornerstones of cancer therapy. However, some types of tumor respond little or hardly at all to radiation. If it were possible to make tumor cells more sensitive, treatment would be more effective and gentler.

10 Mar 2022

Novel nanoparticles enable synergy of radiation and photodynamic therapies of deep tumor tissues

Researchers Dr Yansong Feng and Prof. Hong Zhang at the Van 't Hoff Institute for Molecular Sciences at the University of Amsterdam (UvA) have designed and synthesized novel multi-layered, multi-functional nanoparticles that enable a combination of radiotherapy and photodynamic therapy for deep cancer tissue.

10 Mar 2022

Nanoparticle News and Research

Further Reading

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

UC researcher awarded renewal grant to continue the study of genetic drivers of breast cancer

Self-assembling SARS-CoV-2 spike protein-directed nanoparticle vaccines

Mosaic-8 RBD-nanoparticles show promise as a vaccine candidate for SARS-CoV-2 and potential sarbecoviruses spillovers

The potential efficacy of nasal nanoparticle COVID-19 vaccines

A ferritin nanoparticle candidate vaccine for COVID

Researchers use optoacoustics for high-precision neuromodulation

A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers

New nanoparticle-based COVID-19 vaccine platform could target other infectious diseases

Study discovers potent and selective human monoclonal antibodies against Omicron variant of SARS-CoV-2

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Nanoparticle-enhanced phototherapies for cancer treatment

New way to deliver potential HIV vaccine using mRNA technology

Antimicrobial prescribing among infants may be prevented using maternal RSV vaccines

New approach to send ‘friendly’ nano-particles into the body shows promising results

Lower, more frequent doses of nanomedicines may provide additional benefits for cancer patients

Study indicates a 100 µg mRNA-1273 booster has acceptable safety and robust antibody response against SARS-CoV-2

Using metal oxide nanoparticles as 'radiosensitizers' for gentler cancer treatment

Novel nanoparticles enable synergy of radiation and photodynamic therapies of deep tumor tissues

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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