Narcolepsy News and Research

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Narcolepsy is a chronic sleep disorder, or dyssomnia. The condition is characterized by excessive daytime sleepiness (EDS) in which a person experiences extreme fatigue and possibly falls asleep at inappropriate times, such as while at work or at school.

SK Biopharmaceuticals receives FDA Orphan Drug status for carisbamate

SK Biopharmaceuticals, a South Korean pharmaceutical company, announced today that it was granted special status by the U.S. Food and Drug Administration (FDA) for carisbamate for the management of patients with infantile spasms (IS), a form of epilepsy associated with increased risk of death or mental retardation.

20 Apr 2012

Par Pharmaceutical commences shipment of modafinil tablets

Par Pharmaceutical Companies, Inc. today announced that it began shipping all strengths of modafinil tablets, a generic version of Teva's Provigil brand.

7 Apr 2012

Roaring snores could be sounds of obstructive sleep apnea

Roaring snores that rumble a room or violent snorts for breath during sleep could be sounds of obstructive sleep apnea. While a true diagnosis is only possible with a sleep study, if left untreated, the sleep disorder could be fatal.

28 Mar 2012

SK Biopharmaceuticals initiates YKP10811 phase 2 trial in chronic constipation

SK Biopharmaceuticals, a South Korean pharmaceutical company, announced today that the first patient was dosed in a phase 2 clinical trial in the US for patients suffering with chronic constipation using their new chemical entity YKP10811.

17 Mar 2012

Children with chronic sleep problems may develop mental health disorders later in life

Children who have chronic sleep problems may be much more likely to develop mental health disorders as adolescents and adults, according to Candice Alfano, associate professor in clinical psychology at the University of Houston (UH) and director of the new Sleep and Anxiety Center for Kids (SACK).

11 Jan 2012

Parents blame swine flu vaccine for son’s narcolepsy

A six year old boy’s parents have claimed that he developed narcolepsy after a swine flu vaccination. Caroline Hadfield said son Josh lost muscle control and started sleeping up to 19 hours a day three weeks after being given Pandemrix nearly two years ago.

12 Dec 2011

Protein, not sugar, stimulates cells keeping us thin and awake

A new study has found that protein and not sugar activates the cells responsible for keeping us awake and burning calories. The research, published in the 17 November issue of the scientific journal Neuron, has implications for understanding obesity and sleep disorders.

17 Nov 2011

Scientists discover neurons responsible for light-induced arousal response

Bright light arouses us. Bright light makes it easier to stay awake. Very bright light not only arouses us but is known to have antidepressant effects. Conversely, dark rooms can make us sleepy. It's the reason some people use masks to make sure light doesn't wake them while they sleep.

4 Nov 2011

Scientists identify first DNA faults linked to melanoma

Cancer Research UK scientists have discovered the first DNA faults linked to melanoma - the deadliest skin cancer - that are not related to hair, skin or eye colour, according to research published in Nature Genetics today.

10 Oct 2011

Finland national health institute finds link between H1N1 flu vaccine and children's narcolepsy

"Finland's national health institute said on Thursday its latest research on previously found links between children's narcolepsy and GlaxoSmithKline's Pandemrix vaccine against H1N1 swine flu also involved a genetic risk factor," Reuters reports.

3 Sep 2011

Narcolepsy more prevalent in China during April

New research shows that the occurrence of narcolepsy in China is highly correlated to a seasonal pattern, with onset most frequent in April.

22 Aug 2011

Winter airway infections appear to trigger narcolepsy: Study

The onset of narcolepsy appears to follow seasonal patterns of H1N1 and other upper airway infections, according to a new study of patients in China that was led by Stanford University School of Medicine narcolepsy expert Emmanuel Mignot, MD.

22 Aug 2011

Nacolepsy drugs may be effective in reversing illness-induced lethargy

A signaling system in the brain previously shown to regulate sleep is also responsible for inducing lethargy during illness, according to research conducted at Oregon Health & Science University Doernbecher Children's Hospital.

4 Aug 2011

EMA says link between narcolepsy and Pandemrix 2009 H1N1 vaccine exists

A final review result from Europe's drug regulatory agency released a positive link between narcolepsy and the Pandemrix 2009 H1N1 vaccine. The agency recommends a labeling change that limits the vaccine's use in children and teens to when protection is needed and seasonal trivalent vaccine isn't available.

21 Jul 2011

Omeros identifies compounds that interact with orphan GPCRs associated with leukemia

Omeros Corporation today reported that it has identified compounds that interact with orphan G protein-coupled receptors (GPCRs) P2Y8 and OPN4. P2Y8 (also known as P2RY8) is associated with acute lymphoblastic leukemia (ALL), an aggressive cancer of the white blood cells.

27 Jun 2011

Untreated obstructive sleep apnea can reduce work productivity

Large corporations could save millions of dollars in lost productivity by screening and treating high-risk employees for obstructive sleep apnea, suggests a research abstract that will be presented Monday, June 13, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC.

14 Jun 2011

Natural sleep preference might affect baseball player's batting average in day, night games

A Major League Baseball player's natural sleep preference might affect his batting average in day and night games, according to a research abstract that will be presented Monday, June 13, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC.

14 Jun 2011

Normal sleep duration linked to reduced depression and increased quality of life

Getting six to nine hours of sleep per night is associated with higher ratings for quality of life and lower ratings for depression, suggests a research abstract that will be presented Tuesday, June 14, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC.

14 Jun 2011

Perceived racism linked to elevated risk of self-reported sleep disturbance

Perceived racial discrimination is associated with an increased risk of sleep disturbance, which may have a negative impact on mental and physical health, suggests a research abstract that will be presented Tuesday, June 14, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC.

14 Jun 2011

Later class start times in college linked to delayed sleep schedules, increased drinking and lower grades

Although a class schedule with later start times allows colleges students to get more sleep, it also gives them more time to stay out drinking at night. As a result, their grades are more likely to suffer, suggests a research abstract that will be presented Tuesday, June 14, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC.

14 Jun 2011

Narcolepsy News and Research

Further Reading

SK Biopharmaceuticals receives FDA Orphan Drug status for carisbamate

Par Pharmaceutical commences shipment of modafinil tablets

Roaring snores could be sounds of obstructive sleep apnea

SK Biopharmaceuticals initiates YKP10811 phase 2 trial in chronic constipation

Children with chronic sleep problems may develop mental health disorders later in life

Parents blame swine flu vaccine for son’s narcolepsy

Protein, not sugar, stimulates cells keeping us thin and awake

Scientists discover neurons responsible for light-induced arousal response

Scientists identify first DNA faults linked to melanoma

Finland national health institute finds link between H1N1 flu vaccine and children's narcolepsy

Narcolepsy more prevalent in China during April

Winter airway infections appear to trigger narcolepsy: Study

Nacolepsy drugs may be effective in reversing illness-induced lethargy

EMA says link between narcolepsy and Pandemrix 2009 H1N1 vaccine exists

Omeros identifies compounds that interact with orphan GPCRs associated with leukemia

Untreated obstructive sleep apnea can reduce work productivity

Natural sleep preference might affect baseball player's batting average in day, night games

Normal sleep duration linked to reduced depression and increased quality of life

Perceived racism linked to elevated risk of self-reported sleep disturbance

Later class start times in college linked to delayed sleep schedules, increased drinking and lower grades

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

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