Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Kidney dysfunction in HIV patients can be detected earlier

Tracking the subtle kidney damage that can lead to chronic kidney disease in HIV patients is increasingly important as people survive longer and may have an increased risk of renal dysfunction as a result of their disease, therapy-related damage, or co-morbid conditions such as diabetes mellitus and hypertension.

28 Feb 2005

Up to 500,000 Americans will develop lupus-related kidney disease

According to the Lupus Foundation of America, an estimated 300,000 to 500,000 Americans with the autoimmune disease lupus eventually will develop lupus-related kidney disease, known as lupus nephritis. Lupus nephritis is one of the most serious manifestations of lupus and can lead to serious health problems, kidney failure, disability or death.

27 Feb 2005

Olmesartan improves blood supply to kidneys

How do medications that block the renin-angiotensin system (RAS blockers) work to protect against kidney disease in people with diabetes? At least partly by improving the blood supply to the kidneys, suggests a study in the April Journal of the American Society of Nephrology.

17 Feb 2005

Traditional Indian medicine, herb Salacia oblonga may help treat diabetes

Herbs used in traditional Indian medicine to treat diabetes seems to lower blood sugar and insulin levels in a manner similar to prescription drugs, a new study reports.

8 Feb 2005

Health risks increase in Guyana with leptospirosis

Leptospirosis has become a health concern in Guyana, as the number of cases continues to rise and 43 people were being treated for suspected cases of the bacterial disease, which is usually caused by exposure to water contaminated with the urine of infected animals.

8 Feb 2005

Risks of obesity in children with kidney transplants

Obese children who get kidney transplants tend to be younger, shorter and on dialysis longer than their leaner peers, according to a study in the February issue of the journal Pediatrics.

7 Feb 2005

Genzyme files Glucocerebrosidase patent infringement

Genzyme announced today that it has filed a lawsuit in the District Court of Tel Aviv alleging that Transkaryotic Therapies Inc. has infringed Genzyme's Israeli patent No. 100,715, which covers certain cell culture processes involved in the manufacture of glucocerebrosidase.

25 Jan 2005

High blood pressure risk in African-Americans linked to genetics

National health records have shown that African-Americans are more prone to high blood pressure than Caucasians, but pinning down the roots of that difference has proven elusive. Now, researchers at the Stanford University School of Medicine have narrowed down the search for genes that contribute to this difference in disease risk.

24 Jan 2005

1 billion people with high blood pressure by 2025

The proportion of the world’s adult population with high blood pressure is predicted to increase from a quarter to a third by 2025, totalling over one billion, conclude authors of a study published in this week’s issue of The LANCET.

13 Jan 2005

New guidelines for treating diabetes

Every year, the American Diabetes Association (ADA) issues Clinical Practice Recommendations, a series of updated recommendations to help health care providers treat people with diabetes using the most current research available.

7 Jan 2005

10 to 20 million people in the United States have chronic kidney disease but most don’t know it

10 to 20 million people in the United States have chronic kidney disease but most don’t know it, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Center for Health Statistics.

19 Dec 2004

Thiazolidinedione (TZD) class of anti-diabetic drugs may be a potential targeted therapy for myeloma patients

In laboratory tests on multiple myeloma cells, University of Rochester researchers found that this type of cancer expresses a protein that makes it an easy target for an existing class of diabetes drugs. After more investigation, they hope the discovery will lead to a new, targeted therapy for myeloma patients.

8 Dec 2004

African Americans more likely to carry genetic variants known to stimulate inflammatory response

Specific variants in genes that encode proteins regulating inflammation may hold a key to explaining a host of disease processes known to cause increased risk of illness and death among African Americans, according to a study from the University of Pittsburgh's Graduate School of Public Health (GSPH).

1 Dec 2004

Bypass surgery on a beating heart is an excellent option for many patients with blocked heart arteries

Bypass surgery on a beating heart is an excellent option for many patients with blocked heart arteries, according to a study in Circulation: Journal of the American Heart Association.

24 Nov 2004

Sit down rounds improve outcomes for kidney dialysis patients

"Sit-down" medical rounds, during which a health care team meets to review a patient's medical record and discuss short- and long-term needs, are associated with better outcomes for kidney dialysis patients, a Johns Hopkins-directed study has found.

17 Nov 2004

Too much vitamin supplementation could be harmful

Daily vitamin E doses of 400 international units (IU) or more can increase the risk of death and should be avoided, researchers reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Do cholesterol-reducing drugs decrease the risk of heart attacks and strokes in diabetics?

International researchers will, for the first time, present findings from the landmark 4D trial about whether a cholesterol-reducing drug decreases the risk of heart attacks and strokes with type 2 diabetics on dialysis at the American Society of Nephrology’s 37th Annual Meeting and Scientific Exposition in St. Louis, Missouri.

1 Nov 2004

Interim recommendations on low-carb diets

From the extreme Atkins Diet to the more modest Zone Diet, low carbohydrate diets are all the rage, embraced by celebrities and the general public alike as a quick way to lose weight.

1 Nov 2004

More to MRSA infection than just exposure to antibiotics

Johns Hopkins researchers report potentially life-threatening hospital infections with bacteria resistant to the antibiotic methicillin can occur even if patients havent been treated with that drug.

1 Nov 2004

First ever study in hemodialysis patients to show stable hemoglobin levels

New data confirm that subcutaneous injection of the innovative new anti-anemia agent CERA (Continuous Erythropoietin Receptor Activator) delivers rapid, sustained and stable correction of anemia in a broad spectrum of patients with chronic kidney disease at dosing intervals of up to 4 weeks.

1 Nov 2004