Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Diabetic kidney disease remains one of the most intractable complications of diabetes. Progress has been made using glycemic and blood pressure control, but the search continues for improved treatments for the estimated one in four adults with diabetes who has some level of nephropathy and continues at risk for eventual kidney failure.

10 Nov 2019

New tool accurately predicts risks of death, complications from obesity and diabetes

A new web-based risk calculator can accurately predict the likelihood a patient with type 2 diabetes and obesity will die or develop serious complications including a heart attack, heart failure and diabetic kidney disease (nephropathy) within the next 10 years.

6 Nov 2019

UAB researchers find key role for IgG autoantibodies in IgA nephropathy

The most common form of the kidney disease called glomerulonephritis is IgA nephropathy.

24 Sep 2019

Metabolic surgery improves health in obese diabetics

Paris is hosting the European Society of Cardiology Congress (ESC) meet this year where on the 2nd of September researchers from the Cleveland Clinic reveal that weight loss surgeries in patients with obesity and type 2 diabetes could reduce the risk death and major untoward heart or cardiovascular events or major adverse cardiovascular events (MACE).

3 Sep 2019

Cell-free DNA identifies pathogens and quantifies injuries to organs

A common problem in diagnosing infectious disease is that the presence of a potential pathogen in the body does not necessarily mean the patient is sick. This can be particularly challenging for the treatment of organ transplant recipients, who often grapple with infection as well as complications related to immunosuppression.

29 Aug 2019

How much control is too much in type 1 diabetes?

Type 1 diabetes mellitus (T1DM) affects thousands of children, and causes high sugar levels because of low insulin production. In places with good access to medical care, blood glucose is first measured by capillary blood testing or continuous monitoring. Insulin is given as required by subcutaneous injection or insulin pump.

29 Aug 2019

Study shows how blood glucose levels affect risks in type 1 diabetes

A major new study on the association between blood glucose levels and risks of organ impairment in people with type 1 diabetes can make a vital contribution to diabetes care, in the researchers’ view.

28 Aug 2019

Mini kidneys grown in the lab could be used to better understand kidney diseases

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown 'miniature kidneys' in the laboratory that could be used to better understand how kidney diseases develop in individual patients.

20 Aug 2019

Chronic kidney disease patients are excluded from clinical trials

Kidney diseases affect 850 million people worldwide, a figure twice as high as that of diabetes. Yet patients with chronic kidney disease are still being excluded from clinical trials.

10 Jul 2019

Microvascular disease associated with increased risk of leg amputation

Microvascular disease is independently associated with a higher risk of leg amputation compared to people without the disease, according to new research in the American Heart Association's journal Circulation.

8 Jul 2019

New natural extract inhibits the development of diabetic nephropathy

A team of researchers have published in the Journal of Cellular Physiology that a new natural extract is able to inhibit the development of diabetic nephropathy, a kidney disease that is increasing in incidence throughout the world.

16 Jun 2019

Researchers identify enzymes that protect people from diabetic kidney disease

A new study from Joslin Diabetes Center has proven that certain biological protective factors play a large role in preventing diabetic kidney disease in certain people. The study was published today in Diabetes Care.

21 May 2019

New catalog of DNA mutation 'fingerprints' could help doctors pinpoint cancer culprits

Scientists in Cambridge and London have developed a catalog of DNA mutation 'fingerprints' that could help doctors pinpoint the environmental culprit responsible for a patient's tumor - including showing some of the fingerprints left in lung tumors by specific chemicals found in tobacco smoke.

16 Apr 2019

Novo Biosciences achieves major milestones in its new drug to treat heart disease and DMD

Novo Biosciences Inc., has achieved several major milestones in its mission of bringing its breakthrough drug candidate, trodusquemine, to market as a potential regenerative medicine treatment for heart disease and Duchenne muscular dystrophy.

15 Apr 2019

New research sheds light on how kidney obstruction causes damage and repairs

Scientists seeking to regrow damaged kidneys have discovered that blocked kidneys in newborns have a remarkable ability to repair themselves after the obstruction is removed.

7 Feb 2019

New research tests Co-enzyme Q10 as potential treatment for Chronic Kidney disease

Chronic Kidney disease is highly associated with all-cause mortality, Diabetic Nephropathy, cardiovascular events and hospitalization whether the patient has an existing risk or current cardiovascular disease or not.

28 Dec 2018

Newly designed mice emulate severe form of kidney damage in humans with diabetes

Scientists led by Duke-NUS Medical School have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy.

9 Nov 2018

Previously unknown virus acts as 'driver' for interstitial nephropathy

An international research team led by Wolfgang Weninger, who has been Head of MedUni Vienna's Department of Dermatology since 1 September, has discovered a previously unknown virus that acts as a "driver" for certain kidney diseases (interstitial nephropathy).

14 Sep 2018

Omeros’ OMS721 receives positive opinion from EMA's COMP for treating hematopoietic stem cell transplant

Omeros Corporation announced today that the European Medicines Agency's Committee for Orphan Medicinal Products issued a positive opinion recommending orphan drug designation of OMS721 for treatment in hematopoietic stem cell transplantation.

25 Jul 2018

People with type 2 diabetes more likely to suffer from breathlessness, restrictive lung disease

Breathlessness and conditions of restrictive lung disease (RLD), such as pulmonary fibrosis, may be a late complication of type 2 diabetes.

11 Jul 2018