Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Liver cancers linked to compound popular in herbal remedies

A latest study has shown that Aristolochic Acids (AA) – that are commonly used as a natural product found in some natural remedies, could be associated with liver cancers. Researchers from Singapore and Taiwan showed in their study that AA could be causing mutations in the genes that predispose an individual to liver cancers.

19 Oct 2017

Immunotherapy shows promise in treatment of Type 1 diabetes

Around 1.25 million Americans are living with type 1 diabetes and 40,000 new cases are detected each year. In this condition body’s own immune system attacks and damages the insulin-producing β-cells inside the pancreas leading to impaired glucose metabolism in the body. There is no other treatment for this condition than regular painful insulin injections to maintain the normal insulin levels in the body. Type 1 diabetes is currently considered to be incurable.

10 Aug 2017

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Omeros Corporation today announced that OMS721 has received orphan drug designation from the U.S. Food and Drug Administration for the treatment of Immunoglobulin A (IgA) nephropathy.

4 Aug 2017

Glycated CD59 identified as novel biomarker for screening and diagnosis of gestational diabetes

Mellitus, LLC today reported the publication of results from a prospective, investigator-initiated study conducted at Brigham and Women's Hospital demonstrating the potential clinical utility of glycated CD59 (GCD59) as a novel biomarker for the screening and diagnosis of gestational diabetes mellitus.

28 Apr 2017

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Testing for molecular markers in the urine of kidney transplant patients could reveal whether the transplant is failing and why, according to research presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases.

24 Apr 2017

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

An off-the-shelf dietary supplement available for pennies per dose demonstrated the ability to reverse cellular damage linked to specific genetic mutations in transgenic fruit flies, an experimental model of genetic mutation-induced renal cell injury that features striking similarities to humans, a Children's National Health System research team reports April 20 in Journal of the American Society of Nephrology.

21 Apr 2017

Scientists identify genetic clues to chronic kidney disease

Using international genomic studies backed by proof-of-concept cell experiments, researchers have identified two genes that contribute to the chronic kidney disease glomerulonephritis.

16 Mar 2017

New research reveals link between sickle cell trait and increased risk of developing kidney failure

New research indicates that being born with one copy of the sickle gene puts an individual at elevated risk for developing kidney failure requiring dialysis.

10 Mar 2017

High levels of folate during pregnancy may decrease hypertension risk in children

A new article published in the American Journal of Hypertension finds that babies born to mothers with cardiometabolic risk factors were less likely to develop high blood pressure if their mothers had higher levels of folate during pregnancy.

8 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

Researchers uncover new genetic clues linked to autoimmune kidney disease

Researchers have uncovered new genetic clues to understanding IgA nephropathy (IgAN), or Berger's disease, an autoimmune kidney disease and a common cause of kidney failure.

6 Mar 2017

International consortium aims to improve therapeutic options for diabetes-induced kidney disease

Chronic kidney disease is a frequently encountered disorder: more than 10% of the population suffer from such problems.

3 Mar 2017

FDA approves new nasal spray for adults who overproduce urine at night

The U.S. Food and Drug Administration today approved Noctiva (desmopressin acetate) nasal spray for adults who awaken at least two times per night to urinate due to a condition known as nocturnal polyuria (overproduction of urine during the night).

3 Mar 2017

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Since the discovery of penicillin in 1928, antibiotics have made the world a much safer and healthier place. But Shakespeare was onto something when he asked if it's possible to have too much of a good thing. In the case of antibiotics, the answer is increasingly "yes."

3 Mar 2017

Study finds mobile health clinics as powerful tool to engage patients in care

Patients treated at mobile health clinics report a high level of engagement in their care and the motivation to pursue healthy behaviors, according to the results of a qualitative study led by Zoe Bouchelle, Harvard Medical School Class of 2017, and communications scholar Heather Carmack of James Madison University.

2 Mar 2017

Highly prevalent gene variants in African Americans contribute to kidney disease

African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2 -- in APOL1, a gene that codes for a human-specific protein.

1 Mar 2017

Study reveals high burden of health complications in adolescents, young adults with type 2 diabetes

A new report published in the Feb. 28 issue of the Journal of the American Medical Association points to a significantly higher burden of diabetes-related complications in adolescents and young adults with type 2 diabetes compared to type 1 diabetes, with greater health complications in minority youth.

28 Feb 2017

Nephropathy News and Research

Further Reading

Liver cancers linked to compound popular in herbal remedies

Immunotherapy shows promise in treatment of Type 1 diabetes

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Glycated CD59 identified as novel biomarker for screening and diagnosis of gestational diabetes

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

Scientists identify genetic clues to chronic kidney disease

New research reveals link between sickle cell trait and increased risk of developing kidney failure

High levels of folate during pregnancy may decrease hypertension risk in children

New drug-like compound shows potential to treat symptoms of lupus

Researchers uncover new genetic clues linked to autoimmune kidney disease

International consortium aims to improve therapeutic options for diabetes-induced kidney disease

FDA approves new nasal spray for adults who overproduce urine at night

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Study finds mobile health clinics as powerful tool to engage patients in care

Highly prevalent gene variants in African Americans contribute to kidney disease

Study reveals high burden of health complications in adolescents, young adults with type 2 diabetes

Young children experience better long-term kidney transplant success than adults, study finds

HIV-infected individuals with kidney failure less likely to receive necessary transplant, study finds

Initial diagnosis of acute kidney injury may be inaccurate for many patients, study suggests

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