Nephrotic Syndrome News and Research

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Nephrotic syndrome is characterized by a set of signs and symptoms including proteinuria, low protein levels in the blood, hypercholesterolemia, hypertriglyceridemia, and edema. It may be caused by various disorders of the kidney, and the management of the condition varies according to the specific case and the cause of the symptoms.

Rituximab alters T-cell metabolism in patients with nephrotic syndrome

Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine.

10 Sep 2026

Early treatment helps patient recover from rare kidney disorder

When Bradley Lawrence gained 25 pounds in two weeks and started experiencing chest pain and shortness of breath, he quickly sought care at NYU Langone Hospital—Brooklyn.

31 Mar 2026

Rituximab shows remarkable success in adults with relapsing nephrotic syndrome

One monoclonal antibody, rituximab, can work wonders for the treatment of children with frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome.

5 Nov 2025

Suppression of cdc42 activity could be a promising therapy for nephrotic syndrome

A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and proposed that suppression of cdc42 activity could be a promising therapy for nephrotic syndrome.

6 Aug 2025

New autoimmune target identified in pediatric idiopathic nephrotic syndrome

Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein crucial for kidney cell structure—as a significant factor in INS.

14 Jul 2025

Autoantibodies against vinculin linked to childhood kidney disease

19 Jun 2025

CDC report reveals COPD as the sixth leading cause of death in the U.S.

Chronic lower respiratory diseases, including chronic obstructive pulmonary disease (COPD), are the sixth leading cause of death in the United States, according to the U.S. Centers for Disease Control and Prevention (CDC).

21 Jan 2025

Hybrid technique identifies anti-nephrin autoantibodies as biomarker for kidney disorders with nephrotic syndrome

A groundbreaking study, presented today at the 61st ERA Congress, has uncovered a significant breakthrough in the diagnosis and monitoring of kidney diseases associated with nephrotic syndrome.

25 May 2024

New cellular atlas of the kidney sheds light on disease

Research is shedding light on kidneys, their critical functions, and predictors of disease.

19 Jul 2023

New treatment pathway identified for patients with idiopathic nephrotic syndrome

With funding from charity Kidney Research UK, Dr Carl May from Bristol Medical School and his team have identified a new treatment pathway for patients with non-genetic (idiopathic) nephrotic syndrome (INS), targeting a still unknown factor that causes the progression towards kidney failure.

13 Apr 2023

Cellular and humoral responses and the safety of recombinant and inactivated SARS-CoV-2 vaccines in chronic kidney disease patients

Researchers investigated the B cell and humoral immune responses elicited against inactivated and recombinant SARS-CoV-2 vaccines and their safety profiles in patients with CKD.

8 Feb 2023

New chemical probe can selectively inhibit human COQ8A protein in cells

Inhibition of the COQ8 protein could be beneficial in the treatment of diseases such as cancer. COQ8 is needed for the biosynthesis of coenzyme Q, also known as ubiquinone.

28 Nov 2022

25 years on, varicella vaccination reports impressive success in the USA

New research suggests that 25 years on, varicella vaccination continues to report impressive success in the USA.

26 Oct 2022

Quality improvement program enhances Pneumococcal vaccination rates amongst high risk patients

In this study published in the American Journal of Kidney Diseases (AJKD), a quality improvement program that utilized electronic best practice alerts within the electronic medical record boosted pneumococcal vaccination rates from 53% to 70% (P < 0.001) in adults age 18-64 years with stage 4 and 5 chronic kidney disease.

18 Aug 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

Years of life lost associated with leading causes of US death during the first 20 months of the COVID-19 pandemic

Researchers estimated the years of life lost during the COVID-19 pandemic in the United States.

28 Jul 2022

Phenome study reveals alternate associations with SARS-CoV-2 risk loci

Researchers from the Duke Molecular Physiology Institute have been investigating genetic associations with more severe disease and examining the associations that certain genetic features have with other diseases.

13 Dec 2021

Results of high-impact clinical trials could affect kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online at ASN Kidney Week 2021 November 4–November 7.

7 Nov 2021

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in the kidneys, as well as a protective effect against nephrotic syndrome (NS) by inhibiting apoptosis (cell death) of kidney cells.

30 Nov 2020

High-impact clinical trial results could improve kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25.

23 Oct 2020