Neurodegenerative Diseases News and Research

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Scientists devise new fluorescent probes to diagnose neurodegenerative diseases

Sticky plaques of proteins called amyloids mark several different, though related degenerative brain diseases including Alzheimer's, Parkinson's and Creutzfeld-Jacobs. The symptoms of these disorders overlap and methods to diagnose and monitor them are not very advanced.

16 Aug 2012

Catechins may help reduce neurological complications linked to HIV

Current drug therapy for patients with HIV is unable to control the complete replication of the virus in the brain. The drugs therefore do not have any effect against the complications associated with neurocognitive impairment in patients with HIV. New research by Joseph Steiner and colleagues from Johns Hopkins University has discovered that a group of plant polyphenols known as catechins, which naturally occur in green tea and the seed of the cacao tree, may help in the prevention of these neurological complications.

15 Aug 2012

TXNIP protein provides best available target for therapies against diabetes, Wolfram syndrome

Inflammation and cell stress play important roles in the death of insulin-secreting cells and are major factors in diabetes. Cell stress also plays a role in Wolfram syndrome, a rare, genetic disorder that afflicts children with many symptoms, including juvenile-onset diabetes.

8 Aug 2012

Australia's top medical researchers for 2012 announced

Finalists for one of Australia’s longest running and most prestigious awards for medical research were announced today. This year’s winner will join a list of alumni winners that includes many of the country’s most respected scientists.

31 Jul 2012

Latrepirdine appears effective in treating Alzheimer's disease in animals

An international team of scientists led by researchers at Mount Sinai School Medicine have discovered that a drug that had previously yielded conflicting results in clinical trials for Alzheimer's disease effectively stopped the progression of memory deterioration and brain pathology in mouse models of early stage Alzheimer's disease.

31 Jul 2012

Advanced understanding of neurodegenerative diseases achieved by Trophos

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for indications with under-served needs in neurology and cardiology, announces today the conclusion of the pan-European MitoTarget Project, the EU funded orphan disease project, with submission of the final report to the EC.

31 Jul 2012

Parkinson’s disease treatment: an interview with Ted Dawson

Parkinson’s disease is a disorder which usually affects people in their 60’s and older. It is caused by the loss of dopamine neurons in the brain leading to rigidity, slowness of movement, tremor, problems with balance and so forth.

31 Jul 2012

Scientists identify new gene responsible for genetic form of blindness in newborns

One of the mysteries of blindness has been solved. A team of international scientists in collaboration with the Research Institute of the McGill University Health Centre (RI MUHC) identified a new gene responsible for Leber Congenital Amaurosis (LCA), a devastating genetic form of blindness in newborns.

30 Jul 2012

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Take a millionth of a human brain and squeeze it into a special chamber the size of a mustard seed. Link it to a second chamber filled with cerebral spinal fluid and thread both of them with artificial blood vessels in order to create a microenvironment that makes the neurons and other brain cells behave as if they were in a living brain. Then surround the chambers with a battery of sensors that monitor how the cells respond when exposed to minute quantities of dietary toxins, disease organisms or new drugs under development.

25 Jul 2012

Researchers identify new class of compounds that inhibit spread of prions

A team of University of Alberta researchers has identified a new class of compounds that inhibit the spread of prions, misfolded proteins in the brain that trigger lethal neurodegenerative diseases in humans and animals.

24 Jul 2012

Low-lactose functional milk with ginseng may help improve cognitive function

American ginseng is reported to have neurocognitive effects, and research has shown benefits in aging, central nervous system disorders, and neurodegenerative diseases.

23 Jul 2012

Protein associated with Huntington’s and other neurodegenerative diseases has several brain-specific forms

A protein essential for metabolism and recently associated with neurodegenerative diseases also occurs in several brain-specific forms. This discovery emerged in the course of a research project funded by the Austrian Science Fund FWF, the findings of which have now been published in the journal Human Molecular Genetics.

23 Jul 2012

Scientists uncover how internal mechanisms in nerve cells wire the brain

Scientists at the University of Manchester have uncovered how the internal mechanisms in nerve cells wire the brain. The findings open up new avenues in the investigation of neurodegenerative diseases by analysing the cellular processes underlying these conditions.

21 Jul 2012

Epithilone D effective in preventing Alzheimer's in animal models

While clinical trial results are being released regarding drugs intended to decrease amyloid production - thought to contribute to decline in Alzheimer's disease - clinical trials of drugs targeting other disease proteins, such as tau, are in their initial phases.

20 Jul 2012

Huddersfield scientist receives Pain Relief Foundation grant for research into BH4 pathway

SOME victims of serious illness experience much less pain than other sufferers, thanks to a natural biochemical variation in the cells of their bodies. Now a scientist at the University of Huddersfield has been awarded research funding that will aid his project to learn more about this variation and therefore develop treatments that could lead to the relief of pain for all patients, with much less dependence on drugs that can have distressing side effects.

19 Jul 2012

The Alzheimer's Association recognizes four leading scientists with Lifetime Achievement Award

The Alzheimer's Association recognized four leading scientists for their extraordinary contributions to Alzheimer's disease research at the Alzheimer's Association International Conference (AAIC 2012) in Vancouver, Canada.

16 Jul 2012

Chica and Heinz Schaller Foundation supports work of five new C.H.S. research groups

Five new research groups for young scientists, the C.H.S. research groups, have taken up their work in basic biomedical research. To mark the occasion, the German Cancer Research Center (DKFZ) will hold a ceremony on 20 July 2012.

14 Jul 2012

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Two powerful brain chemical systems work together to paralyze skeletal muscles during rapid eye movement (REM) sleep, according to new research in the July 11 issue of The Journal of Neuroscience. The finding may help scientists better understand and treat sleep disorders, including narcolepsy, tooth grinding, and REM sleep behavior disorder.

12 Jul 2012

Oligodendroglia cells: An interview with Jeffrey Rothstein

There are three principle cells in the brain: neurons and two types of glial cells. One type is called an astrocyte. These were well known to inactivate neurotransmitters like glutamate, and provide metabolic support to neurons.

11 Jul 2012

Research into “insulating” brain cells could help to cure neurodegenerative diseases such as ALS

Johns Hopkins researchers say they have discovered that the central nervous system's oligodendroglia cells, long believed to simply insulate nerves as they "fire" signals, are unexpectedly also vital to the survival of neurons. Damage to these insulators appears to contribute to brain injury in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease for the Yankee baseball great who died from the disease.

11 Jul 2012

Neurodegenerative Diseases News and Research

Scientists devise new fluorescent probes to diagnose neurodegenerative diseases

Catechins may help reduce neurological complications linked to HIV

TXNIP protein provides best available target for therapies against diabetes, Wolfram syndrome

Australia's top medical researchers for 2012 announced

Latrepirdine appears effective in treating Alzheimer's disease in animals

Advanced understanding of neurodegenerative diseases achieved by Trophos

Parkinson’s disease treatment: an interview with Ted Dawson

Scientists identify new gene responsible for genetic form of blindness in newborns

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Researchers identify new class of compounds that inhibit spread of prions

Low-lactose functional milk with ginseng may help improve cognitive function

Protein associated with Huntington’s and other neurodegenerative diseases has several brain-specific forms

Scientists uncover how internal mechanisms in nerve cells wire the brain

Epithilone D effective in preventing Alzheimer's in animal models

Huddersfield scientist receives Pain Relief Foundation grant for research into BH4 pathway

The Alzheimer's Association recognizes four leading scientists with Lifetime Achievement Award

Chica and Heinz Schaller Foundation supports work of five new C.H.S. research groups

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Oligodendroglia cells: An interview with Jeffrey Rothstein

Research into “insulating” brain cells could help to cure neurodegenerative diseases such as ALS

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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