Neurodegenerative Diseases News and Research

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Polyunsaturated lipids can alter binding rate of two receptors involved in Parkinson's and Alzheimer's

A study published in the prestigious journal Scientific Reports from the Nature group demonstrates, for the first time and using computational tools, that polyunsaturated lipids can alter the binding rate of two types of receivers involved in certain nervous system diseases.

2 Mar 2016

Novel therapeutic approach to target monomeric Tau protein

Dementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.

27 Feb 2016

Study: Magnesium therapy can alleviate muscular symptoms in patients with Motor Neurone Disease

Around 5,000 Motor Neurone Disease (MND) sufferers across the UK could find relief to their muscular symptoms thanks to transdermal (through the skin) magnesium therapy, say health pioneers BetterYou.

From BetterYou Ltd 25 Feb 2016

UEA research paves way for new wave of drugs to kill superbugs

Scientists at the University of East Anglia are getting closer to solving the problem of antibiotic resistance.

24 Feb 2016

Researchers identify common molecular alteration in glioblastoma

Glioblastoma is the most aggressive manifestation of brain tumours. Due to its high invasive capacity and uncontrolled, infiltrating growth, it is particularly difficult to manage. Currently, the treatment for this disease consists of a combination of surgery (when possible), radiation and chemotherapy.

22 Feb 2016

Small peptide TAxI holds promise for carrying biologic drugs into spinal cord

A small peptide dubbed TAxI is living up to its name. Recent studies show it to be an effective vehicle for shuttling functional proteins, such as active enzymes, into the spinal cord after a muscle injection.

17 Feb 2016

Innovative tool helps observe protein aggregates linked to neurodegenerative diseases

For rent: 32 individual rooms for a combined surface area of 4cm2, heating and food included! Biologists and microfluidics specialists at EPFL have joined forces and developed a highly innovative research tool: a 2cm by 2cm 'chip' with 32 independent compartments, each of which is designed to hold a nematode - a widely used worm in the research world. The device is described in the journal Molecular Neurodegeneration.

16 Feb 2016

Unlocking intrinsically disordered proteins: an interview with Peter Wright

I'm a professor in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute. I have been performing NMR research on proteins for nearly 40 years.

From Bruker BioSpin - NMR, EPR and Imaging 11 Feb 2016

Lamin nucleoskeleton disordered in Alzheimer's

Brain cell death in Alzheimer's disease is linked to disruption of a skeleton that surrounds the nucleus of the cells, a researcher in the School of Medicine at The University of Texas Health Science Center at San Antonio said.

5 Feb 2016

Study finding could shed light on molecular mechanisms underlying Huntington's disease

Researchers at the University of Pittsburgh School of Medicine have shown that the core of the protein clumps found in the brains of people with Huntington's disease have a distinctive structure, a finding that could shed light on the molecular mechanisms underlying the neurodegenerative disorder.

4 Feb 2016

Stopping disruptions in cellular 'trash removal' may guard against neurodegenerative diseases

Stopping disruptions in cellular "trash removal" brought on by errors in molecular marks on DNA may guard against neurodegenerative diseases like Parkinson's.

27 Jan 2016

Chronic exposure to environmental toxin may up risk of neurodegenerative illness

A new study published today in the science journal Proceedings of the Royal Society B indicates that chronic exposure to an environmental toxin may increase risk of neurodegenerative illness. Conducted by scientists at the Institute for EthnoMedicine, a non-profit medical research organization, and the University of Miami Brain Endowment Bank, the study provides a foundation for future research in Alzheimer's disease, ALS and Parkinson's disease.

25 Jan 2016

UAB study shows IL-37 protein suppresses inflammatory response after spinal cord injury

Spinal cord injuries cause severe functional disabilities in those who sustain them, including paraplegia or tetraplegia, depending on the scale of the injury. This is due to the degeneration of the spinal pathways that carry nerve signals from the brain to the different parts of the body and vice versa, resulting in loss of mobility and sensitivity underneath the injured area.

22 Jan 2016

Oestrogen supplements could reduce dementia risk in women

Women who take oestrogen supplements from before or at the start of menopause and continue with them for a few years have better preserved brain structure, which may reduce the risk of dementia.

22 Jan 2016

Oxeia accelerating development of neurometabolic treatments for concussions

Oxeia Biopharmaceuticals, Inc., a biotechnology company, is catalyzing the development of first-in-class neurometabolic treatments for concussions and other aspects of brain injury.

21 Jan 2016

Findings may explain why type 2 diabetic patients experience smelling problems

In a study in type 2 diabetic rats, researchers at the Karolinska Institutet have identified alterations in specific nerve cells that are important for odor identification. The findings might explain why type 2 diabetic patients often experience smelling problems and potentially open up a new research field to develop preventive therapies against neurodegenerative diseases in type 2 diabetic patients.

21 Jan 2016

Neurodegenerative Diseases News and Research

Polyunsaturated lipids can alter binding rate of two receptors involved in Parkinson's and Alzheimer's

Novel therapeutic approach to target monomeric Tau protein

Study: Magnesium therapy can alleviate muscular symptoms in patients with Motor Neurone Disease

UEA research paves way for new wave of drugs to kill superbugs

Researchers identify common molecular alteration in glioblastoma

Small peptide TAxI holds promise for carrying biologic drugs into spinal cord

Innovative tool helps observe protein aggregates linked to neurodegenerative diseases

Unlocking intrinsically disordered proteins: an interview with Peter Wright

Lamin nucleoskeleton disordered in Alzheimer's

Study finding could shed light on molecular mechanisms underlying Huntington's disease

Stopping disruptions in cellular 'trash removal' may guard against neurodegenerative diseases

Chronic exposure to environmental toxin may up risk of neurodegenerative illness

UAB study shows IL-37 protein suppresses inflammatory response after spinal cord injury

Oestrogen supplements could reduce dementia risk in women

Oxeia accelerating development of neurometabolic treatments for concussions

Findings may explain why type 2 diabetic patients experience smelling problems

High-traffic 'hub neurons' may play role in understanding brain health

Dartmouth investigators show how vestibular system's horizontal canals influence navigation

Common mortality causes prevail in epilepsy patients

New UTMB study reveals link between traumatic brain injury and Alzheimer's disease

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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