Neurodegenerative Disorder News and Research

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New project improves timely administration of drugs to hospitalized Parkinson's patients

Timely administration of anti-Parkinson drugs is a significant issue for hospitalized patients with Parkinson's disease (PD) with late or missed doses resulting in longer stays and worse outcomes.

9 Jul 2020

Parkinson's disease breakthrough seen in mouse model

Researchers from the University of California San Diego School of Medicine have found a way to create new neurons in a mouse model of Parkinson's disease. The severely debilitating and progressive neurodegenerative disease, as of now, has no cure, and this breakthrough could help hundreds of thousands of patients with the condition feel experts.

25 Jun 2020

AFFiRiS AG announces results of phase 1 trial with PD01A in Parkinson's

AFFiRiS AG, a clinical-stage biotechnology company developing novel disease-modifying specific active immunotherapies (SAITs), today announced that detailed results of the phase 1 clinical program with its lead candidate PD01 in early Parkinson's disease (PD) patients were published in the peer-reviewed journal The Lancet Neurology.

18 Jun 2020

Irregular circadian rhythm in older adults associated with increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

15 Jun 2020

AFFiRiS announces preclinical results of monoclonal antibody mAB C6-17 in Huntington's

AFFiRiS, a clinical-stage biotechnology company developing novel disease-modifying specific active immunotherapies, today announced that detailed preclinical results with its monoclonal antibody mAB C6-17 to treat Huntington's Disease were published in the peer-reviewed journal Neurobiology of Disease.

3 Jun 2020

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

28 May 2020

Molecular pair offers hope for development of new Parkinson's treatment

A promising molecular pair has offered hope that could lead to the development of a new treatment to slow down Parkinson's disease, a study by Nanyang Technological University, Singapore and Harvard University has found.

27 May 2020

Inherited genetic variations can alter progression of melanoma, indicates study

Sometimes cancer stays put, but often it metastasizes, spreading to new locations in the body. It has long been suspected that genetic mutations arising inside tumor cells drive this potentially devastating turn of events.

26 May 2020

New trial platform could help evaluate potential therapies for Parkinson’s disease

Despite 30 years of research, not a single therapy has been found to successfully delay or stop the progression of Parkinson's disease.

6 May 2020

Caffeine consumption can protect against Parkinson’s disease, shows study

Two purines, caffeine and urate, have been associated with a reduced risk of Parkinson's disease (PD) in multiple study groups and populations.

6 May 2020

Study shows lower caffeine, urate levels are inversely linked to Parkinson’s disease

Analysis of participants in the Harvard Biomarkers Study highlights the inverse association between low caffeine consumption and blood urate levels and PD, report scientists in the Journal of Parkinson's Disease.

5 May 2020

Cells from the gut's nervous system found to be involved in Parkinson's disease

Researchers at Karolinska Institutet in Sweden and the University of North Carolina in the USA have mapped out the cell types behind various brain disorders.

27 Apr 2020

Solving the mystery of unidentified late-onset neurodegenerative disorder

When a patient with puzzling neurological symptoms enrolled in the Undiagnosed Diseases Network, researchers led by Dr. Hugo J. Bellen were set on solving the mystery.

16 Apr 2020

Experts highlight the impact of COVID-19 pandemic on patients with Parkinson’s disease

While much attention has focused on the potential for severe respiratory complications and unfavorable outcomes from the COVID-19 pandemic among patients with Parkinson's disease (PD), the impact extends beyond these threats.

5 Apr 2020

Study of rare genetic disorder that causes severe eyesight problems

Nagano prefecture is home to a group of people effected with a rare genetic neurodegenerative disorder called familial amyloid polyneuropathies. This disease impacts the gene encoding protein transthyretin which is produced in the liver and also eyes.

3 Apr 2020

Gene that could affect the progress of ALS discovered

Researchers from the Zuckerman Institute at Columbia University have successfully found a gene that could work towards accelerating the progression of ALS or amyotrophic lateral sclerosis. The study titled, "The loss of TBK1 kinase activity in motor neurons or in all cell types differentially impacts ALS disease progression in SOD1 mice," was published in the latest issue of the journal Neuron.

29 Mar 2020