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Unexpected protein-protein interaction suggests new ALS drug target

Discovery of an unexpected protein-protein interaction has led University of Iowa scientists and colleagues to identify a drug that slows the progression of Amyotrophic Lateral Sclerosis (ALS) in mice and nearly doubles the animals' lifespan.

25 Jan 2008

New MIT tool probes brain circuits

Researchers at the Picower Institute for Learning and Memory at MIT report in the Jan. 24 online edition of Science that they have created a way to see, for the first time, the effect of blocking and unblocking a single neural circuit in a living animal.

25 Jan 2008

Researchers identify five genes with possible protective capabilities against a Parkinson's disease trait

University of Alabama researchers have identified five genes within animal models displaying protective capabilities against a hallmark trait of Parkinson's disease.

25 Jan 2008

Deafness and seizures result when glutamate protein deleted in mice

Scientists have discovered that mice genetically engineered to lack a particular protein in the brain have profound deafness and seizures.

25 Jan 2008

Computer vision may not be as good as thought

For years, scientists have been trying to teach computers how to see like humans, and recent research has seemed to show computers making progress in recognizing visual objects.

25 Jan 2008

Researchers identify brain's 'eureka' circuitry

Researchers have found the brain region that controls the decision to halt your midnight exploration of the refrigerator and commence enjoyment of that leftover chicken leg.

24 Jan 2008

Genetic roots of obesity

A discovery by Queen's biologists and their students sheds new light on the genetic roots of obesity a condition that is increasing dramatically in North America and has been linked to heart disease, diabetes and some forms of cancer.

24 Jan 2008

Genetic difference predicts antidepressant response

Researchers have identified subtle genetic variations that predict the efficacy of two widely used antidepressant drugs.

24 Jan 2008

Gene therapy for pain

Researchers in the Department of Medicine and Department of Neurosciences at Mount Sinai School of Medicine have discovered that chronic pain can be successfully treated with novel targeted gene therapy.

23 Jan 2008

Cell division studies hint at future cancer therapy

When a cell's assets get divided between daughter cells, Dr. Quansheng Du wants to make sure both offspring do well.

23 Jan 2008

Stem cell research aims to tackle Parkinson's disease

Scientists in Sweden are developing new ways to grow brain cells in the laboratory that could one day be used to treat patients with Parkinson's disease, an international conference of biologists organised by the European Science Foundation (ESF) was told last week.

21 Jan 2008

Sleep plays a critical role in the brain's ability to learn

Most people know it from experience: After so many hours of being awake, your brain feels unable to absorb any more-and several hours of sleep will refresh it.

21 Jan 2008

Previously unknown chromosomal abnormalities play substantial role in autism

Genome-wide scans of families affected by autism spectrum disorder (ASD) have revealed new evidence that previously unknown chromosomal abnormalities have a substantial role in the prevalent developmental disorder, according to a report published online Jan. 17th in the American Journal of Human Genetics, a publication of Cell Press.

18 Jan 2008

Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway

Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which plays an important role in Alzheimer's disease.

18 Jan 2008

New auditory cortex research may bring better hearing aids and more effective speech recognition systems

Recognising people, objects or animals by the sound they make is an important survival skill and something most of us take for granted.

15 Jan 2008

A good night's sleep could improve long-term memory

Scientists from the Medical Research Council's Anatomical Neuropharmacology Unit (ANU) at the University of Oxford have discovered evidence that sleep is important for the stabilisation of memory.

14 Jan 2008

Two different neural pathways regulate loss and regain of consciousness during general anesthesia

University of Pennsylvania School of Medicine researchers have answered long-running questions about the way that anesthetics act on the body, by showing that the cellular pathway for emerging from anesthesia is different from the one that drugs take to put patients to sleep during operations.

14 Jan 2008

Ringing in the ears

Do your ears ring after a loud concert? Nerves that sense touch in your face and neck may be behind the racket in your brain, University of Michigan researchers say.

11 Jan 2008

Asf1, the protein that oversees DNA replication and packaging in the cell

At the Institut Curie, the CNRS team of Genevieve Almouzni has just discovered how the protein Asf1 ensures the correct (re)organization of duplicated DNA. During DNA replication, all the information in the mother cell must be transmitted to the daughter cells.

11 Jan 2008