Neuropathic Pain News and Research

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Neuropathic pain is a type of pain that is caused by damage to the nervous system following an injury or illness and affects approximately 1% of the population.

Effective dose of cannabidiol for safe pain relief without the typical 'high'

In the wake of cannabis legalization, a team of scientists at the Research Institute of the McGill University Health Center and McGill University have delivered encouraging news for chronic pain sufferers by pinpointing the effective dose of marijuana plant extract cannabidiol for safe pain relief without the typical "high" or euphoria produced by the THC.

25 Oct 2018

Nerve-on-a-chip platform could help improve neuroprosthetic designs

Neuroprosthetics - implants containing multi-contact electrodes that can substitute certain nerve functionalities - have the potential to work wonders.

23 Oct 2018

Novartis: Lancet publishes pioneering study of Aimovig’s efficacy in episodic migraine patients

Novartis announced today that the full data from the LIBERTY study of Aimovig (erenumab) in episodic migraine patients who had tried and failed two to four prior preventive treatments have been published in the Lancet.

23 Oct 2018

Salk researchers advance sonogenetics technology for treating neurological conditions

The emerging technology of sonogenetics--a technique where cells are controlled by sound--offers the potential to one day replace pharmaceutical drugs or invasive surgical treatments for neurological conditions like epilepsy, Parkinson's disease or posttraumatic stress disorder.

23 Oct 2018

Antiepileptic drug use associated with elevated stroke risk in Alzheimer’s patients

Antiepileptic drug use is associated with an increased risk of stroke among persons with Alzheimer’s disease, according to a new study from the University of Eastern Finland. The risk did not differ between old and new antiepileptic drugs.

10 Oct 2018

New pre-clinical research shows utility of mRNA platform to treat rare metabolic disorders

An mRNA platform that can express therapeutic levels of protein in liver tissue could be used to treat patients with rare metabolic disorders.

9 Oct 2018

Damage to small nerves shown to be cause of chronic pain following knee surgeries

Patients frequently experience severe chronic pain following knee operations. Although the pain is thought to be due to damage to small nerves, it was hitherto impossible to demonstrate this by imaging.

8 Oct 2018

T-CALM Phase 2 clinical study results offer hope for essential tremor patients

Cavion, Inc., a leading clinical stage biotechnology company committed to developing novel therapeutics for people with neurological diseases, today announced promising results of the T-CALM Phase 2 clinical trial of its first-in-class T-type calcium channel modulator CX-8998 in essential tremor.

7 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Common painkiller not effective in controlling chronic pain after traumatic nerve injury

A new study out today in the Journal of Neurology finds that pregabalin is not effective in controlling the chronic pain that sometimes develops following traumatic nerve injury.

25 Sep 2018

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval from the Japanese Ministry of Health, Labour and Welfare for ADCETRIS (brentuximab vedotin) in combination with doxorubicin, vinblastine and dacarbazine as a frontline treatment option for CD30-positive Hodgkin lymphoma patients in Japan.

24 Sep 2018

Cannabinoid drugs reduce perceived unpleasantness of painful stimuli and increase tolerance

Researchers in the College of Arts and Sciences have determined that cannabinoid drugs do not appear to reduce the intensity of experimental pain, but, instead, may make pain feel less unpleasant and more tolerable.

19 Sep 2018

Novel clinical trial to examine cannabis as potential treatment for essential tremor

Researchers at University of California School of Medicine are preparing to launch a novel clinical trial to examine the safety, efficacy and pharmacological properties of cannabis as a potential treatment for adults with essential tremor.

18 Sep 2018

Non-opioid drug shows promise for treating pain by targeting receptors on immune cells

Faced with the epidemic of opioid addiction, researchers have been charged with finding other strategies to treat pain. Their efforts largely have focused on nerve cells that transmit pain signals to the spinal cord and brain.

6 Jul 2018

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

Scientists have used CRISPR-Cas9 gene editing to lessen some autism symptoms in mice with a form of fragile X syndrome, the most common known single-gene cause of autism spectrum disorder.

25 Jun 2018

Kessler Foundation scientists receive four grants to expand scope of research in spinal cord injury

The New Jersey Commission on Spinal Cord Injury Research has awarded four grants to scientists at Kessler Foundation.

12 Jun 2018

Single spinal injection reverses chemotherapy-induced pain for months in mice

Researchers at University of California San Diego School of Medicine have found a new way to block a root cause of pain. The key is a naturally occurring protein called apolipoprotein A-I binding protein (AIBP). AIBP binds to toll-like receptor 4 (TLR4), a protein that sits on the surface of cells like an antenna, searching for signs of infection or tissue damage.

29 May 2018

Researchers uncover novel approach for treating neuropathic pain

Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer.

4 May 2018

Scientists successfully test anti-alcoholism drug in animal models

Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink.

4 May 2018

Study to examine whether cannabidiol provides therapeutic benefit to children with autism

Researchers at University of California San Diego School of Medicine are preparing a first-of-its-kind, multidisciplinary investigation to determine if and how cannabidiol, a non-psychoactive compound found in the cannabis plant, provides therapeutic benefit to children with severe symptoms of autism spectrum disorder.

27 Apr 2018

Neuropathic Pain News and Research

Further Reading

Effective dose of cannabidiol for safe pain relief without the typical 'high'

Nerve-on-a-chip platform could help improve neuroprosthetic designs

Novartis: Lancet publishes pioneering study of Aimovig’s efficacy in episodic migraine patients

Salk researchers advance sonogenetics technology for treating neurological conditions

Antiepileptic drug use associated with elevated stroke risk in Alzheimer’s patients

New pre-clinical research shows utility of mRNA platform to treat rare metabolic disorders

Damage to small nerves shown to be cause of chronic pain following knee surgeries

T-CALM Phase 2 clinical study results offer hope for essential tremor patients

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Common painkiller not effective in controlling chronic pain after traumatic nerve injury

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Cannabinoid drugs reduce perceived unpleasantness of painful stimuli and increase tolerance

Novel clinical trial to examine cannabis as potential treatment for essential tremor

Non-opioid drug shows promise for treating pain by targeting receptors on immune cells

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

Kessler Foundation scientists receive four grants to expand scope of research in spinal cord injury

Single spinal injection reverses chemotherapy-induced pain for months in mice

Researchers uncover novel approach for treating neuropathic pain

Scientists successfully test anti-alcoholism drug in animal models

Study to examine whether cannabidiol provides therapeutic benefit to children with autism

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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