Nicotine News and Research

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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.

Nabi Biopharmaceuticals reports first-quarter net income of $5.5 million from continuing operations

Nabi Biopharmaceuticals today announced its first quarter financial results for the three month period ended March 27, 2010. The Company reported net income from continuing operations of $5.5 million, or $0.11 per share, compared to a net loss of $7.0 million, or $0.14 per share, for the period ended March 28, 2009.

7 May 2010

New research to improve effectiveness of nicotine vaccination for cigarette smokers

If Pradeep K. Garg, Ph.D., of Wake Forest University Baptist Medical Center figures out why some smokers are more addicted to nicotine than others, it could lead to more successful smoking cessation treatments.

6 May 2010

Non-daily use of tobacco can trigger nicotine dependency among adolescents

Kids who have just started smoking, but not on a daily basis, don't seem to recognize the early symptoms of dependence, according to a new study.

4 May 2010

Prenatal tobacco smoke exposure can increase risk of developmental problems in African American children

Low levels of prenatal tobacco smoke exposure are associated with a higher risk of developmental problems for African American children than white children, according to new research from Cincinnati Children's Hospital Medical Center.

4 May 2010

Majority of children living in apartments are exposed to secondhand smoke

The majority of children living in apartments are exposed to secondhand smoke, even when they don't live with smokers. This study from the University of Rochester Medical Center is the first to examine whether housing type is a potential contributor to children's exposure to cigarette smoke.

3 May 2010

Hullabaloo over the tobacco tax hike and planned plain cigarette packaging law

The Australian Federal Government this week announced an increase in taxes by 25% on cigarettes to discourage smoking and generate funds for more antismoking measures. In a new development Federal Opposition Leader Tony Abbott announced that the Coalition will support this move.

29 Apr 2010

CocE exhibits potential for clinical treatment of cocaine toxicity

Cocaine toxicity due to drug overdose results in more than half a million emergency room visits annually. Despite these alarming statistics, there is no Food and Drug Administration-approved pharmacotherapy specifically designed to treat cocaine toxicity. Emergency medical personnel are limited to treating only the immediate life-threatening symptoms of patients, while toxic levels of cocaine and its metabolic break-down products persist and continue to damage the cardiovascular system, liver and brain.

27 Apr 2010

First patient enrolled in Phase II clinical trial of E10030 for treatment of wet age-related AMD

Ophthotech Corp., a privately held biopharmaceutical company focused on developing ophthalmic therapies for back-of-the-eye diseases, today announced that the first patient has been enrolled in its Phase II randomized, controlled clinical trial of E10030, an anti-PDGF aptamer, in combination with Lucentis® for the treatment of wet age-related macular degeneration (AMD).

26 Apr 2010

Santaris Pharma advances into drug development SPC5001 research candidate against PCSK9

Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies, today announced that it has advanced into drug development a discovery research candidate directed against PCSK9 (proprotein convertase subtilisin/kexin type 9), an important new target for the treatment of high cholesterol. Using its proprietary Locked Nucleic Acid (LNA) Drug Platform and Drug Discovery Engine, Santaris Pharma A/S identified and advanced the new drug, SPC5001, in just 18 months.

26 Apr 2010

DeCODE scientists discover common SNPs that increase number of CPD and risk of lung cancer

Cigarette smoking is a major cause of illness and death worldwide. But it is a complex behavior, and how much people smoke, how hard they find it to quit, and the impact of long-term smoking on health varies greatly among individuals. A substantial portion of this variability is genetic. Two years ago, deCODE discovered the first common, single-letter variation in the sequence of the human genome, on chromosome 15q25, associated with nicotine addiction and risk of lung cancer.

26 Apr 2010

Report shares what women need to know and what women can do

Lung Cancer Alliance hailed today's release of "Out of the Shadows: Women and Lung Cancer," a groundbreaking report issued by the Mary Horrigan Connors Center at Brigham and Women's Hospital, a teaching affiliate of Harvard Medical School.

26 Apr 2010

Three genetic regions associated with cigarette smoking

A team of scientists has used data from genome-wide association studies to identify genetic variants associated with key smoking behaviors that have a significant impact on health.

26 Apr 2010

Genes that predispose to smoking behavior and lung cancer identified: More reason to quit say researchers

According to new research there are certain genes in a smoker that make it difficult for them to cut down or quit the bad habit. This report from three studies published in the journal Nature Genetics mentions at least three different genetic mutations on chromosome 15 or changes that can increase the number of cigarettes smoked per day by an individual.

25 Apr 2010

Nicotine poisoning linked to weight gain

A new study links nicotine poisoning with weight gain, and concludes tha active smokers, not only those who stop, put on more weight than non-smokers. After four years of analysis in the University of Navarra, those who put on least weight were those who had never smoked.

23 Apr 2010

New multi-faceted treatment program for young adults addicted to opioid drugs

A multi-faceted treatment program for young adults addicted to opioid drugs was unveiled today at the National Institute on Drug Abuse's Blending Conference in Albuquerque, N.M. This eighth meeting in the series brings together researchers and clinicians so their latest findings can be immediately applied to the needs of patients and their families dealing with addictive disorders.

23 Apr 2010

Researchers receive grant to help people living with mental illness tackle tobacco dependence

Researchers at The University of Nottingham have won government funding to improve the services which help people living with serious mental illness to tackle their tobacco dependence.

22 Apr 2010

GUMC researchers awarded grant to discover and develop new smoking cessation drugs

A Georgetown University Medical Center research team has been awarded a grant from the National Institute on Drug Abuse to discover and develop new smoking cessation drugs based on an unconventional theory about nicotine addiction. Kenneth Kellar, PhD, a professor of pharmacology at GUMC is principal investigator of the five year grant totaling $4.6 million.

22 Apr 2010

Stopping smoking may be harder than quitting heroin

An addiction is an addiction and it may be tougher to quit smoking cigarettes compared to beating a heroin addiction. An Australian study found that many long term smokers have tried to quit 7.4 times but are still unable to do so. Sydney GP Raymond Seidler actually feels that people do not realize that quitting smoking is just as bad as kicking heroin out of your life.

22 Apr 2010

FDA-approved metformin can prevent tobacco-carcinogen induced lung tumors: Study

Metformin, a mainstay of treatment for patients with type 2 diabetes, may soon play a role in lung cancer prevention if early laboratory research presented here at the AACR 101st Annual Meeting 2010 is confirmed in clinical trials.

20 Apr 2010

Healthyroads announces new partnership status with NAQC

Healthyroads, the wellness subsidiary of American Specialty Health Incorporated, announced its new partnership status with the North American Quitline Consortium and its approval to serve as an authorized quitline vendor in the state of Michigan.

19 Apr 2010

Nicotine News and Research

Further Reading

Nabi Biopharmaceuticals reports first-quarter net income of $5.5 million from continuing operations

New research to improve effectiveness of nicotine vaccination for cigarette smokers

Non-daily use of tobacco can trigger nicotine dependency among adolescents

Prenatal tobacco smoke exposure can increase risk of developmental problems in African American children

Majority of children living in apartments are exposed to secondhand smoke

Hullabaloo over the tobacco tax hike and planned plain cigarette packaging law

CocE exhibits potential for clinical treatment of cocaine toxicity

First patient enrolled in Phase II clinical trial of E10030 for treatment of wet age-related AMD

Santaris Pharma advances into drug development SPC5001 research candidate against PCSK9

DeCODE scientists discover common SNPs that increase number of CPD and risk of lung cancer

Report shares what women need to know and what women can do

Three genetic regions associated with cigarette smoking

Genes that predispose to smoking behavior and lung cancer identified: More reason to quit say researchers

Nicotine poisoning linked to weight gain

New multi-faceted treatment program for young adults addicted to opioid drugs

Researchers receive grant to help people living with mental illness tackle tobacco dependence

GUMC researchers awarded grant to discover and develop new smoking cessation drugs

Stopping smoking may be harder than quitting heroin

FDA-approved metformin can prevent tobacco-carcinogen induced lung tumors: Study

Healthyroads announces new partnership status with NAQC

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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