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Large-scale study maps the genetic underpinnings of early TB progression

While the vast majority of the 1.8 billion people infected with the TB bacterium never experience active disease, an estimated 5 to 15 percent do develop full-blown infections--roughly half of them within 18 months of exposure.

4 Sep 2019

SATI gene editing could replace CRISPR

Scientists have developed a new gene editing tool called SATI that is safer than CRISPR.

2 Sep 2019

Harnessing power of CRISPR to control behavior of DNA-responsive materials

The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide position of the vast reaches of the genome.

23 Aug 2019

Study finds genetic links to childhood obesity across different ethnicities

An international team of researchers who analyzed data across multiple ethnicities has produced the largest genetic study to date associated with common childhood obesity.

22 Aug 2019

New method prevents the release of synthetic DNA from genetically modified cells

The method prevents a gene that encodes a synthetic protein from spreading into the wild and stabilizes it so that it cannot mutate and lose its function.

21 Aug 2019

Extremely drug resistant bacteria spreading through hospitals

A new study found that a common bacterium responsible for chest infections and sepsis in sick people, and which fails to respond to the strongest antibiotics, is spreading through hospital contacts.

30 Jul 2019

Whole-genome sequencing could transform salmonella detection

Salmonella is among the most common organisms responsible for symptomatic and serious food poisoning. Methods to detect this have evolved from crude microscopic identification to serotype detection.

29 Jul 2019

Group of genes linked to longer lifespan in fruit flies discovered

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS, the Engelgard's Institute of molecular biology of RAS and Moscow Institute of Physics and Technology published a scientific article titled "Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity" in Nature Scientific Reports - the leading international multidisciplinary weekly journal.

19 Jul 2019

Researchers identify brain somatic mutations linked to Alzheimer's disease

Researchers have identified somatic mutations in the brain that could contribute to the development of Alzheimer's disease. Their findings were published in the journal Nature Communications last week.

18 Jul 2019

Scientists discover how resistance to the chemotherapy drug 5-fluorouracil arises

Australian researchers have unlocked the mystery as to why the chemotherapy drug 5-Fluorouracil is not effective at treating certain cancers.

17 Jul 2019

Study explores role of iron in over 900 diseases

In a series of early-stage studies examining genetic data from over 500,000 people, a team of international scientists, led by Imperial College London, explored the role that iron plays in over 900 diseases.

17 Jul 2019

Research sheds light on sun-induced DNA damage and repair

It is a well known fact that the sun’s ultraviolet rays can damage the skin. Now, a new study sheds light on what happens after DNA damage occurs, and how the body initiates repair.

15 Jul 2019

Study reveals time taken for DNA repair after chemotherapy

In the time it takes for an Amazon Prime delivery to arrive, cells damaged by chemotherapy can almost completely fix their most important DNA. That is the case in the livers of mice at least, according to a new study.

2 Jul 2019

Researchers develop new technique to image cell populations and genetic contents

Researchers have come up with a new way to image cell populations and their genetic contents. Their study, appearing June 20 in the journal Cell, describes how a technique called DNA microscopy helps illuminate the spatial organization of genetic material within cells and tissues without specialized, expensive optical equipment.

24 Jun 2019