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Natera's Panorama™ NIPT now offered by Biopticka Laborator in Czech Republic

Natera (NTRA), a leader in non-invasive genetic testing and the analysis of circulating cell-free DNA, and Biopticka Laborator, one of the largest and most well-established laboratories in the Czech Republic, today announced a Constellation™ technology transfer licensing agreement that enables Biopticka Laborator to leverage Natera’s proprietary single nucleotide polymorphism-based (SNP) technology to screen for fetal aneuploidies.

From Natera 2 Aug 2017

Large clinical study reveals the performance of Natera's Panorama® non-invasive prenatal test

Natera, Inc. a leader in non-invasive genetic testing and the analysis of circulating cell-free DNA, today announced the publication of a large clinical experience study evaluating the performance of the company's Panorama® non-invasive prenatal test (NIPT).

From Natera 31 Jul 2017

Researchers uncover 16 genetic markers linked to decreased lifespan

The answer to how long each of us will live is partly encoded in our genome. Researchers have identified 16 genetic markers associated with a decreased lifespan, including 14 new to science. This is the largest set of markers of lifespan uncovered to date.

27 Jul 2017

Genetic variation linked to greater tuberculosis susceptibility

Researchers have shown that a single nucleotide change in a gene that affects production of hepcidin--a peptide involved in inflammation, immunity, and control of iron levels--is associated with greater susceptibility to extrapulmonary tuberculosis.

21 Jul 2017

Finnish mothers carry rare gene variants that protect them from pre-eclampsia, study finds

Researchers at the University of Helsinki, in cooperation with two research groups in the United States, have discovered that some Finnish mothers carry rare gene variants that protect them from pre-eclampsia, also known as toxaemia of pregnancy.

3 Jul 2017

Study explores factors, patterns that predict use of restrictive feeding for children

In the preschool years, children begin to learn from their environment about self-regulation--both in regards to food choices and how to deal with their emotions.

16 Jun 2017

Study shows how RNA splicing errors may trigger development of ALS, FTD

The most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)- rare and related neurological disorders marked by progressive deterioration of motor or cognitive abilities- may be due to errors in RNA splicing, an intermediary step for translating genetic instructions into functional proteins.

14 Jun 2017

UAB researchers demonstrate persistence of donor microbes in recipients after fecal transplant

University of Alabama at Birmingham researchers have made the first direct demonstration that fecal donor microbes remained in recipients for months or years after a transplant to treat the diarrhea and colitis caused by recurrent Clostridium difficile infections -- a serious and stubborn cause of diarrhea after an antibiotic treatment for some other illness.

14 Jun 2017

Scientists create method for mapping genome-wide DNA damage caused by chemical carcinogen

Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage at high resolution across the genome.

13 Jun 2017

Gene editing technology can introduce hundreds of unintended mutations, study shows

As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.

29 May 2017

Clinical study tests 100-year-old drug in children with autism spectrum disorder

In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

26 May 2017

Scientists identify ten new genetic variants linked to cardiac structure and function

Strong or weak, big or small - variations in our genome play a decisive part in how our heart is shaped and works.

24 May 2017

Scientists identify new risk genes providing insights about cause of CAD

Coronary artery disease (CAD) is a leading cause of death worldwide. Despite dozens of regions in the genome associated with CAD, most of the genetic components of heart diseases are not fully understood, suggesting that more genes are out there to be found.

23 May 2017

Newly identified biomarkers could help predict cognitive deficits in Parkinson's disease patients

New biomarkers identified by a research team in the Perelman School of Medicine at the University of Pennsylvania could help predict which Parkinson's disease patients will suffer significant cognitive deficits within the first three years of their diagnosis.

18 May 2017

Researchers identify many dangerous strains of TB pathogens

Researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences (VIGG) and the Moscow Institute of Physics and Technology have established a catalog of mutations in 319 virulence genes of mycobacteria that cause tuberculosis.

16 May 2017

Guardant Health introduces new initiative to sequence tumor DNA of one million cancer patients

Guardant Health, the world leader in comprehensive liquid biopsies, announced an ambitious goal to sequence the tumor DNA of more than 1 million cancer patients within five years.

15 May 2017

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

Genotyping of patients with advanced cirrhosis from hepatitis C virus could help health-care professionals predict the likelihood of improvement after successful hepatitis C treatment, thus minimizing the need for liver transplants.

8 May 2017

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Myriad Genetics, Inc. and Clovis Oncology, Inc. have announced a companion diagnostic collaboration to support a post-marketing regulatory commitment related to Clovis’ PARP inhibitor, Rubraca. Financial terms of the deal were not disclosed.

3 May 2017

Researchers identify new rare genetic variants linked to extreme longevity

The search for the genetic determinants of extreme longevity has been challenging, with the prevalence of centenarians (people older than 100) just one per 5,000 population in developed nations.

25 Apr 2017

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Biogen today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion recommending the granting of a marketing authorization for SPINRAZA to treat patients with spinal muscular atrophy (SMA).

21 Apr 2017