Nucleotide News and Research

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Evolutionary roadmap revealed: How SARS-CoV-2 adapted and evolved over three years

The evolutionary trends of amino acid alterations at a population scale.

16 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

Scientists capture first images of ribosome-modifying enzymes in action

Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes.

14 Aug 2023

Exploring DNA methylation biomarkers of multiple sclerosis

Researchers identify cell-specific DNA methylation signatures associated with MS.

14 Aug 2023

Significant association found between the rs1205 T-Dom genotype and risk of COVID-19 death or hospitalization among American Indians

Researchers identify an association between the C-reactive protein gene variant rs1205 and COVID-19 severity.

14 Aug 2023

Identification of plasma proteins associated with ovarian cancer risk

Researchers performed proteomic Mendelian randomization as well as co-localization analyses to identify drug targets for ovarian cancer.

8 Aug 2023

Study finds genetic overlap between IBS, gastrointestinal diseases, and psychiatric disorders

Researchers characterized the genetic architecture of IBS and investigated genetic overlap with gastrointestinal and psychiatric phenotypes.

8 Aug 2023

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

Researchers describe the virological range of persistent SARS-CoV-2 infection in immunosuppressed individuals.

7 Aug 2023

Similarities in gene expression between post-mortem and living human brains

Researchers compare human prefrontal cortex gene expression between living and post-mortem samples.

7 Aug 2023

Neoantigen discovery sheds light on cancer immunogenicity

Researchers reported a proteogenomic approach to investigate fresh solid melanoma tumor material.

4 Aug 2023

Can genome editing transform ocular disease treatment?

The discovery and development of gene-editing technologies and their applications in managing ocular diseases.

3 Aug 2023

Is there clinical value in screening healthy children with genome sequencing compared with a gene panel for medically actionable pediatric conditions?

Researchers compared the efficacy of proactive genome sequencing and a medically actionable gene panel in identifying potential risk for pediatric-onset disorders in healthy newborns and children.

2 Aug 2023

What are the mediators linking cardiometabolic risk factors and severe COVID-19?

Researchers performed a genome-wide association study to explore whether biomarker levels are causally related to COVID-19 hospitalization.

2 Aug 2023

Cancer's silent progression: research delves into evolutionary clues in breast cancer

Researchers performed phylogenetic analyses to trace the evolution of breast cancer and precursor lesions.

2 Aug 2023

Novel algorithm characterizes RNA motifs in SARS-CoV and SARS-CoV-2

Researchers developed a novel algorithm to analyze large genomic datasets of RNA viruses, applying it to SARS-CoV-2 and SARS-CoV.

1 Aug 2023

Insights into the relationship between COVID-19 and mental health

Researchers investigated the causal consequences and genetic mechanisms that link the results of SARS-CoV-2 to anxiety disorders.

1 Aug 2023

Research reveals surprising genetic overlap between neurological and psychiatric disorders

Researchers compared the shared genetic risk and biological foundations of neurological and mental illnesses.

1 Aug 2023

Mutational accessibility: A key driver of viral evolution

The influenza (flu) virus is constantly undergoing a process of evolution and adaptation through acquiring new mutations.

29 Jul 2023

Cryo-EM study elucidates 3D structure and molecular mechanism of platelet drug transporter

A research team led by Prof. CHEN Yuxing and Prof. ZHOU Cong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) recently utilized single-particle cryogenic electron microscopy (cryo-EM) to decipher the 3D structure and molecular mechanism of the platelet drug transporter ABCC4.

28 Jul 2023

How do De novo sequencing, QTL mapping, WGS, and lcWGS empower breakthroughs in agrigenomics

Sequencing technology is playing an increasingly important role in agriculture, including crops, livestock and poultry, aquatic organisms, and more.

From MGI 27 Jul 2023

Nucleotide News and Research

Evolutionary roadmap revealed: How SARS-CoV-2 adapted and evolved over three years

Genetic determinants of retinol circulation and their impact on health

Scientists capture first images of ribosome-modifying enzymes in action

Exploring DNA methylation biomarkers of multiple sclerosis

Significant association found between the rs1205 T-Dom genotype and risk of COVID-19 death or hospitalization among American Indians

Identification of plasma proteins associated with ovarian cancer risk

Study finds genetic overlap between IBS, gastrointestinal diseases, and psychiatric disorders

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

Similarities in gene expression between post-mortem and living human brains

Neoantigen discovery sheds light on cancer immunogenicity

Can genome editing transform ocular disease treatment?

Is there clinical value in screening healthy children with genome sequencing compared with a gene panel for medically actionable pediatric conditions?

What are the mediators linking cardiometabolic risk factors and severe COVID-19?

Cancer's silent progression: research delves into evolutionary clues in breast cancer

Novel algorithm characterizes RNA motifs in SARS-CoV and SARS-CoV-2

Insights into the relationship between COVID-19 and mental health

Research reveals surprising genetic overlap between neurological and psychiatric disorders

Mutational accessibility: A key driver of viral evolution

Cryo-EM study elucidates 3D structure and molecular mechanism of platelet drug transporter

How do De novo sequencing, QTL mapping, WGS, and lcWGS empower breakthroughs in agrigenomics

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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