Nucleotides News and Research

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Researchers step closer to cure for common childhood cancer

Acute lymphoblastic leukemia (ALL) is a malignant disease caused by the abnormal growth and development of white blood cells (WBC) in the bone marrow and blood. ALL is the most common cancer occurring in children with an annual rate of approximately 30 to 40 new cases per million.

5 Dec 2004

DNA provides key to successful quitting smoking

Smokers who want to quit now have up to nine times greater chance of doing so, thanks to new DNA testing launched today by Oxford University’s newest spin-out, G-Nostics.

4 Dec 2004

New research into nicotine addiction

The National Institute on Drug Abuse has awarded a $2.1 million contract to Perlegen Sciences, Inc., to investigate the human genome for DNA variations and candidate genes associated with nicotine addiction.

24 Nov 2004

New role for a key protein involved in muscle contraction

Overturning a scientific stereotype, researchers at the University of Illinois at Chicago have discovered a new role for a key protein involved in muscle contraction and shown it is present not just in the cytoplasm of cells but in the nucleus as well.

1 Nov 2004

Single nucleotide polymorphisms and forensic genetics, maybe not such a perfect combination

Forensic genetics is the branch of genetics that, through DNA analysis and comparison, deals with the resolution of legal problems such as paternity tests.

21 Oct 2004

More efficient method to sequence the human genome

Researchers at Baylor College of Medicine have been tabbed to find a more efficient method to sequence the human genome.

18 Oct 2004

Discovery of naturally occurring RNA "switches" that manage the amino acid glycine

Two University of Washington computer scientists are part of a team that has discovered a pair of rare, naturally occurring RNA "switches" in a class of bacteria that work cooperatively to manage the amino acid glycine.

11 Oct 2004

RiboNovix secures license to novel anti-infective discovery technology from Wayne State University

New biotechnology company, RiboNovix, Inc., is addressing the worsening problem of antibiotic-resistant bacteria by developing new anti-infectives that are less susceptible to drug resistance.

5 Oct 2004

3 year study to validate bladder cancer test

A three-year study to validate a test to detect the recurrence of bladder cancer has been initiated by the National Cancer Institute (NCI), at 12 centers across the United States and Canada.

4 Oct 2004

Researchers pinpoint genetic cause of Timothy syndrome

Howard Hughes Medical Institute researchers have pinpointed the genetic cause of a devastating but rare childhood disorder, called Timothy syndrome, which underlies a form of severe cardiac arrhythmia.

4 Oct 2004

Studies of human genetic variation have found strong evidence for the action of natural selection

One of the most comprehensive studies of the forces that have shaped patterns of human genetic variation has found strong evidence for the action of natural selection, which may help explain why certain people are at risk for a variety of conditions and others are not.

8 Sep 2004

New IBM technology could bring the promise of personalized medicine one step closer

Using a basic computer language, the researchers created a "smart" DNA stream that contains a patient's entire medical record

8 Sep 2004

Flaw in DNA helps explain cancers and aging

Their finding explains how oxidative DNA damage - a process long believed to underlie cancers and aging - can create permanent genetic damage.

30 Aug 2004

Finnish company discovers over 200 new genes

Finnish company Jurilab has announced the completion of a genome-wide scan in Acute Myocardial Infarction in the East Finland Founder Population.

12 Aug 2004

Personalised medicine designed to enhance people's chances of quitting smoking

The latest spin-out from the University of Oxford, G-Nostics, focuses on personalised medicine designed to enhance people's chances of quitting smoking.

6 Aug 2004

U.S. scientists have found the genetic basis for one form of sudden infant death syndrome

Sudden infant death syndrome, also known as cot death and crib death, is defined as the death of an infant between the ages of one month and one year which remains unexplained after a thorough postmortem, investigation of the death scene and review of the clinical history.

20 Jul 2004

First international server to analyze genetic diversity on a large scale

Researchers from the Universitat Autònoma de Barcelona have developed the first international server that allows the user to analyze genetic diversity on a large scale.

19 Jul 2004

Molecular mechanisms behind XsalF's anterior specifying activity

Embryologists have long been interested in working out the means by which this regionalization is achieved, and for years the dominant theory has involved a two-step mechanism in which neural tissues are first induced lengthwise down the entire body axis, followed by a transformation step where a second signal specifies the posterior identities of the neural tissue

13 Jul 2004

The structure of AGT shows how one human protein reduces the potency of chemotherapy

The fine details of this x-ray structure may help scientists find ways to fight certain cancers, such as brain tumors, which express high levels of AGT making them resistant to chemotherapy.

9 Jul 2004

Identification of a naturally occurring genetic difference that controls the production of serotonin in the brain

Researchers at Duke University Medical Center have provided the first direct evidence in mice for the role of an enzyme that specifically controls the production of serotonin in the brain.

8 Jul 2004