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Study compares adoptive T-cell therapy with drug-based cancer treatment

In the treatment of large tumors, how effective is adoptive T cell therapy in comparison to drug-based cancer treatment? To answer this question, Dr. Kathleen Anders and Professor Thomas Blankenstein of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch and researchers of the Beckman Research Institute of the City of Hope Cancer Center in Duarte, California, USA designed and carried out a study comparing the two methods. Based on a mouse cancer model, the researchers elucidated the mechanisms of the two different treatments.

18 Jan 2012

Interdisciplinary panel reviews U.S. nitrogen pollution trends, risks and mitigation strategies

Nitrogen is both an essential nutrient and a pollutant, a byproduct of fossil fuel combustion and a fertilizer that feeds billions, a benefit and a hazard, depending on form, location, and quantity. Agriculture, industry and transportation have spread nitrogen liberally around the planet, say sixteen scientists in the latest edition of ESA's Issues in Ecology series, "Excess Nitrogen in the U.S. Environment: Trends, Risks, and Solutions," with complex and interrelated consequences for ecological communities and our dependence upon the resources they provide, as well as human health.

17 Jan 2012

Nutrient Rich Foods approach to eating promotes healthful shopping, eating patterns

With the obesity epidemic impacting American health care, a new study led by Karen Glanz, Ph.D., M.P.H., at the University of Pennsylvania Perelman School of Medicine and the School of Nursing, researchers at RTI International, and the Nutrient Rich Foods Coalition found that educating consumers to use the Nutrient Rich Foods approach to eating is an effective means of promoting healthful shopping and eating patterns, and improving diet quality.

13 Jan 2012

Natural options against weight gain, sugar cravings, and insulin resistance

The holidays have come and gone, but many of us may still be battling intense sweet cravings leftover from the season's festivities. Excessive sugar cravings can be a sign that your blood glucose levels are out of balance which, if left unchecked, can lead to insulin resistance and Metabolic Syndrome, also known as "Pre-Diabetes."

11 Jan 2012

Clearside Biomedical receives $4M venture capital investment

Technology developed by researchers at the Georgia Institute of Technology and Emory University for delivering drugs and other therapeutics to specific locations in the eye provides the foundation for a startup company that has received a $4 million venture capital investment.

6 Jan 2012

Isis announces results from ISIS-TTRRx Phase 1 study on TTR amyloidosis

Isis Pharmaceuticals, Inc. announced today results from a Phase 1 study with ISIS-TTRRx. The results demonstrated that treatment with ISIS-TTRRx produced dose-dependent statistically significant reductions of greater than 80 percent in transthyretin (TTR) protein.

6 Jan 2012

Child malnutrition rates 'alarming' in Somali refugee camps, AFP reports

"Aid workers say malnutrition rates among children under five at the Dolo Ado camp [in Ethiopia] are alarming," with "[o]ver 50 percent of children in Dolo Ado's Hilaweyn camp and nearly half of all children in Kobe camp … suffering from malnutrition, according to a preliminary health survey from the United Nations refugee agency," Agence France-Presse reports.

5 Jan 2012

Mitochondrial dysfunction in tissue stem cells can cause aging-associated degeneration

Aging-related tissue degeneration can be caused by mitochondrial dysfunction in tissue stem cells. The research group of Professor Anu Suomalainen Wartiovaara at the University of Helsinki, with their collaborators in Max Planck Institute for Biology of Aging, Karolinska Institutet and University of Wisconsin, reported on the 3rd January in Cell Metabolism their results on mechanisms of aging-associated degeneration.

4 Jan 2012

Vitamins and omega 3 fatty acids in blood could stave off dementia: Study

A new study has shown that higher blood levels of omega-3 fatty acids, vitamin B, vitamin C, vitamin D and vitamin E are associated with better mental functioning in the elderly.

3 Jan 2012

Hormone Adiponectin linked to dementia in women: Study

New research has shown that there may be a possible connection between a hormone found in body fat and the risk of dementia, adding to the growing evidence on the potential link between the condition and diabetes.

3 Jan 2012

Healthy diet keeps the brain sharp

The study shows that elderly who followed this diet had less of the brain shrinkage linked with Alzheimer's disease and scored better on mental and thinking tests than those with poorer diets. Although previous studies have suggested that a heart-healthy diet is also good for the brain, the new study took a different approach by using blood tests to determine the participant’s diet and nutrient levels.

29 Dec 2011

Free, low-cost strategies to maintain good health in the new year

With the start of a new year, Dana-Farber Cancer Institute experts are encouraging people to ring in new healthy habits and offer a number of free and low-cost strategies to help people maintain good health and possibly reduce various cancer risks.

29 Dec 2011

Seniors with higher levels of vitamins and omega 3 fatty acids perform better on mental acuity tests

New research has found that elderly people with higher levels of several vitamins and omega 3 fatty acids in their blood had better performance on mental acuity tests and less of the brain shrinkage typical of Alzheimer's disease - while "junk food" diets produced just the opposite result.

29 Dec 2011

Diets high in vitamins or omega 3 fatty acids reduce brain shrinkage

People with diets high in several vitamins or in omega 3 fatty acids are less likely to have the brain shrinkage associated with Alzheimer's disease than people whose diets are not high in those nutrients, according to a new study published in the December 28, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

29 Dec 2011

Researchers evaluate role of Mediterranean diet ingredients in prevention of cell damage

The researchers evaluated the role of Mediterranean diet ingredients in the prevention and mitigation of cell damage.

23 Dec 2011

Low-gluten beers can cause symptoms in patients with celiac disease

Beer tested in a new study, including some brands labeled "low-gluten," contains levels of hordein, the form of gluten present in barley, that could cause symptoms in patients with celiac disease (CD), the autoimmune condition treated with a life-long gluten-free diet, scientists are reporting.

22 Dec 2011

Scientists discover missing link between body's biological clock and sugar metabolism system

Scientists have discovered a missing link between the body's biological clock and sugar metabolism system, a finding that may help avoid the serious side effects of drugs used for treating asthma, allergies and arthritis.

20 Dec 2011

Blocking EETs may represent novel strategy for cancer therapy

Recent findings in mice suggest that blocking the production of small molecules produced in the body, known as epoxyeicosatrienoic acids (EETs), may represent a novel strategy for treating cancer by eliminating the blood vessels that feed cancer tumors.

20 Dec 2011

ONC gives gift with vision to reduce blindness and mortality among children

This holiday season, Ocean Nutrition Canada (ONC) is giving a gift with vision. ONC, the largest supplier of Omega-3 EPA/DHA ingredients in the world, is helping to reduce blindness and mortality amongst children in the developing world by donating five million doses of vitamin A to Vitamin Angels.

15 Dec 2011

Scientists discover how intestinal tract influences B cells to prevent infection

Researchers at the University of Toronto have found an explanation for how the intestinal tract influences a key component of the immune system to prevent infection, offering a potential clue to the cause of autoimmune disorders like rheumatoid arthritis and multiple sclerosis.

13 Dec 2011