Omicron News and Research

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Long-term protection and high efficacy of bivalent BA.1 booster confirmed in older adults

Researchers estimated the duration of protection with monovalent vaccination and the efficacy of bivalent vaccine boosters.

5 Apr 2023

Study indicates an increased likelihood of COVID-19-associated hospitalization among children living in rural areas

Researchers investigated characteristics of SARS-CoV-2 infections related to pediatric hospitalizations.

4 Apr 2023

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

In a recent study, researchers assessed serological and mucosal immunity among three differing cohorts.

4 Apr 2023

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Researchers discover a small molecule drug candidate that could provide immediate protection against infection with SARS-CoV-2.

4 Apr 2023

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

Researchers conduct a cross-sectional survey to estimate SARS-CoV-2 antibodies in children.

3 Apr 2023

Updated booster shots vital for keeping COVID-19 in check

Between natural infection and a global vaccination campaign, most people now have some immunity against the virus that causes COVID-19.

3 Apr 2023

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Researchers screened the circulating B lymphocyte repertoires of coronavirus disease 2019 convalescents and vaccines using multiplexed antigen panels.

3 Apr 2023

Tighter core of SARS-CoV-2 spike protein in new variants may have increased the virus's fitness

Just as a tight core is a component of good physical fitness for humans, helping to stabilize our bodies, mutations that tightened the core of the SARS-CoV-2 spike protein in new variants may have increased the virus's fitness.

31 Mar 2023

Do two or more mRNA vaccine doses provide additional protection in patients with prior COVID-19 infection?

Researchers conducted a retrospective cohort study among vaccinated and unvaccinated COVID-19 patients between December 16, 2020, and March 15, 2022, in the USA.

30 Mar 2023

Study finds that current antiviral drugs retain efficacy against newly emerged Omicron subvariants

Researchers assessed the efficacy of antiviral medications against novel Omicron subvariants.

30 Mar 2023

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

The authors of a new study under review at the journal Scientific Reports and currently posted to the Research Square preprint* server proposed a novel analysis pipeline to help identify mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription-polymerase chain reaction (RT-PCR) primer regions.

29 Mar 2023

Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

A team of scientists led by the Department of Energy's Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

28 Mar 2023

New nanomaterials-based sensor detects flu and COVID-19 in just 10 seconds

Have a cough, sore throat and congestion? Any number of respiratory viruses could be responsible. Conventional tests can identify certain likely culprits by relying on chemical reactions, but some researchers want to swap chemistry for electrical changes sensed by nanomaterials.

28 Mar 2023

Study investigates the antigenic and viral receptor-binding properties of major Omicron BA.2.75 subvariants

Researchers in the US examined the neutralization evasion and receptor affinity properties of SARS-CoV-2 Omicron BA.2.75 sub-variants.

28 Mar 2023

New study suggests broad neutralizing antibody could provide three years of COVID protection

In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.

27 Mar 2023

COVID-19 infant hospitalizations reduced by a 3rd maternal vaccine dose during pregnancy

Researchers investigated the effects of the booster coronavirus disease 2019 (COVID-19) vaccine during pregnancy on COVID-19-related hospitalization rates among infants.

27 Mar 2023

Chronological and biological age may be important determinants of vaccine-preventable outcomes

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "Parsing chronological and biological age effects on vaccine responses."

27 Mar 2023

Reinfections with Omicron VOCs occur more frequently and over shorter intervals

In a recent study published in Nature's Communications Biology journal, researchers in the United States of America (USA) employed next-generation sequencing (NGS) data to assess the rise in reinfections with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant.

23 Mar 2023

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

In a recent study posted to the medRxiv* preprint server, researchers in France compared the efficacy of Pfizer-BioNTech Original/BA.4-5 bivalent vaccine compared to messenger ribonucleic acid (mRNA) Original (ancestral) monovalent vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Mar 2023

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

In a recent study posted to the medRxiv* preprint server, researchers examined associations between coronavirus disease 2019 (COVID-19) outcomes and mucosal antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and viral RNA levels in pregnant individuals.

22 Mar 2023

Omicron News and Research

Long-term protection and high efficacy of bivalent BA.1 booster confirmed in older adults

Study indicates an increased likelihood of COVID-19-associated hospitalization among children living in rural areas

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

Updated booster shots vital for keeping COVID-19 in check

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Tighter core of SARS-CoV-2 spike protein in new variants may have increased the virus's fitness

Do two or more mRNA vaccine doses provide additional protection in patients with prior COVID-19 infection?

Study finds that current antiviral drugs retain efficacy against newly emerged Omicron subvariants

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

New nanomaterials-based sensor detects flu and COVID-19 in just 10 seconds

Study investigates the antigenic and viral receptor-binding properties of major Omicron BA.2.75 subvariants

New study suggests broad neutralizing antibody could provide three years of COVID protection

COVID-19 infant hospitalizations reduced by a 3rd maternal vaccine dose during pregnancy

Chronological and biological age may be important determinants of vaccine-preventable outcomes

Reinfections with Omicron VOCs occur more frequently and over shorter intervals

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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