Osteoblast News and Research

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University of Akron researcher awarded NSF grant to study bone remodeling

Osteoporosis is a disease categorized by brittle bones and increased risk of fracture. Individuals with osteoporosis, and diseases like it, have access to a number of treatments but no permanent solution.

9 Oct 2017

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

A major health problem in older people is age-associated osteoporosis -- the thinning of bone and the loss of bone density that increases the risk of fractures. Often this is accompanied by an increase in fat cells in the bone marrow.

22 Sep 2017

Steroid hormones could provide new insight into age-related bone loss

A group of steroid hormones could provide new insight into the bone loss and deterioration that occurs with aging, researchers at the Medical College of Georgia at Augusta University report.

15 Sep 2017

‘Nanokicking’ technology allows scientists to grow 3D mineralized bone tissue

Researchers from the Universities of Glasgow, Strathclyde, the West of Scotland and Galway have grown three-dimensional samples of mineralized bone from human mesenchymal stem cells for the first time without typical osteoinductive media.

15 Sep 2017

Tiny tears in membranes of bone cells may be key to strong bones

The force gravity and physical activity put on our bones causes tiny tears in the membranes of the tiny cells that enable us to make or break down bone, scientists say.

29 Aug 2017

Targeting bone marrow protein could be effective way to improve stem cell transplants

Bone marrow contains hematopoetic stem cells, the precursors to every blood cell type. These cells spring into action following bone marrow transplants, bone marrow injury and during systemic infection, creating new blood cells, including immune cells, in a process known as hematopoiesis.

28 Aug 2017

Researchers compare bone-healing effects of three low-dose growth factors

Researchers compared the effects of three bone growth factors to bone morphogenetic protein 2 (BMP2) -- the most commonly used agent for repair of large bone defects, which is not without risks at the doses required--and showed significant bone-healing effects including the formation of new blood vessels at low doses relative to BMP2.

28 Jul 2017

Long-term chronic bone loss occurs even after one time malaria infection

Malaria caused by Plasmodium parasites is a life-threatening infectious disease that kills at least half a million people annually while causing over 200 million new infections.

2 Jun 2017

Switching off glucocorticoid signaling in bone could protect against diet-induced metabolic disturbances

A high-calorie diet, even without a high amount of fat, causes bone loss, and both high-calorie and high-fat diets induce excessive fat gain and insulin resistance, a new study conducted in mice finds.

4 Apr 2017

Researchers develop biomaterials from apple waste for regeneration of bone, cartilage tissues

Researchers from UPM and CSIC have employed waste from the agri-food industry to develop biomaterials that are able to act as matrices to regenerate bone and cartilage tissues, which is of great interest for the treatment of diseases related to aging.

30 Mar 2017

Researchers use mathematical modeling to raise density of bones badly degraded by osteoporosis

They may seem rigid and set in their ways, but your bones are actually under constant construction and deconstruction. They give up their nutrient treasures (calcium) to the body and then rebuild in a constant give-and-take sort of rhythm.

29 Mar 2017

South Asian women could be at greater risk of developing osteoporosis in later life, study finds

Pre-menopausal South Asian women could be more at risk of developing osteoporosis in later life than white Caucasian women, a new study in the Journal Bone reports.

21 Mar 2017

Hormone secreted by bone cells can suppress appetite, mice study reveals

A hormone secreted by bone cells can suppress appetite, according to mouse studies conducted by Columbia University Medical Center researchers.

8 Mar 2017

Exercise-induced irisin could regulate bone metabolism by autocrine mechanisms

Two weeks of voluntary wheel running induces higher expression of irisin--a fat-burning hormone that is released during exercise--in bone tissue in mice.

3 Mar 2017

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal that the bone marrow niche where HSC's form also ages, contributing to the problem.

3 Mar 2017

New study examines print quality of different composite 3D-printed bone scaffolds

A new study of bone formation from stem cells seeded on 3D-printed bioactive scaffolds combined with different mineral additives showed that some of the scaffold mineral composites induced bone-forming activity better than others.

13 Feb 2017

New method of repairing injured bone could lead to powerful treatments for skeletal system injuries

A recent study, affiliated with UNIST has developed a new method of repairing injured bone using stem cells from human bone marrow and a carbon material with photocatalytic properties, which could lead to powerful treatments for skeletal system injuries, such as fractures or periodontal disease.

8 Feb 2017