Osteoblast News and Research

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Vitamin D shows promise in targeting aging's biological mechanisms, study finds

What is currently known about the potential effect of vitamin D (VitD) on modulating some hallmarks of aging.

26 Mar 2024

YAP and TAZ proteins guide bone development in the womb

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

4 Jan 2024

The effects of vitamin K on bone health

Existing scientific data on the effects of vitamin K (VK) on bone health and elucidated the underlying mechanisms.

30 Nov 2023

Study links lower testosterone levels with increased arthritis risk

The relationship between serological testosterone levels and arthritis among United States (US) adults.

9 Nov 2023

Yabing Chen receives NIH grants to advance vascular disease research

Yabing Chen, Ph.D., has been awarded two National Institutes of Health grants totaling more than $5 million to further her research into vascular diseases ranging from hardening of the arteries to dementia.

6 Nov 2023

Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

In a study published in the journal Genes & Diseases, researchers from Army Medical University and Shenzhen University investigated the pivotal role of miR-18a-5p, a microRNA, in the development and progression of osteoblastic lesions resulting from prostate cancer (PCa) bone metastasis.

9 Oct 2023

Could your gut microbiome shape your teenage years? New study dives into the lifelong health impact

Research explores how the gut microbiota impacts critical areas of adolescent development, including mental health, metabolism, and skeletal growth. It suggests that understanding these interactions could lead to microbiome-based treatments for optimal growth and maturation.

7 Sep 2023

Can smoking cigarettes alter your bone structure?

Researchers aimed to understand how exposure to cigarette smoke causes alterations in bone structure.

2 May 2023

Study opens new therapeutic avenues for treatment of rheumatoid arthritis

A research team, led by Professor Sung Ho Park in the Department of Biological Sciences at UNIST announced the results of a study on osteoblasts that damage joint bones in patients with rheumatoid arthritis.

31 Jan 2023

Enzyme inhibition reduces cancer-related bone loss and the number of bone metastases

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University Medical Center Mannheim and the University Medical Center Hamburg Eppendorf has now identified an enzyme that controls the activity of osteoblasts.

20 Dec 2022

Treg transplantation improves bone remodeling, study says

The building blocks of a structure consist of load-bearing elements that rarely change despite renovations or repairs. They remain intact and consistent over time, but in the human body, our building blocks do just the opposite.

13 Sep 2022

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Bone tissue homeostasis is maintained by a balance between bone formation by osteoblasts and bone resorption by osteoclasts.

23 May 2022

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A.

18 Apr 2022

Researchers discover new mechanisms for bone loss in gum disease

Tokyo University of Agriculture and Technology researchers reported on a new discovery regarding the mechanisms for bone loss in gum disease (periodontitis). They found that double stranded RNA molecules can activate the immune system response that leads to deterioration of bone.

8 Apr 2022

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

A research team led by Prof. Chen Di from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences along with other collaborators have revealed the molecular mechanisms behind bone loss caused by chronic liver injury.

1 Mar 2022

Osteoblast-derived vesicles regulate the switch from bone formation to resorption via a miRNA-mediated mechanism

Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown.

25 Feb 2022

Cellular protein may be a potential new target for treating osteoporosis

A cellular protein whose normal function appears to suppress bone formation may be a potential new target for treating osteoporosis, suggests a collaborative study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Sep 2021

UH associate professor receives $2.5 million to explore how arterial hardening starts within cells

In diseases such as hypertension, aging, atherosclerosis, diabetes and chronic kidney disease, arterial calcification and stiffening of the elastic layer of the arterial wall are almost always present.

30 Aug 2021

Researchers discover many genetic markers related to bone mineral accrual

A multidisciplinary team of researchers led by Children's Hospital of Philadelphia (CHOP) has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing.

6 Jan 2021

Researchers discover potential cellular target for eliminating bone breakdown in osteoporosis

New research has discovered a cell type that governs the way bones form and maintain themselves, opening up a potential target for future therapies for bone disorders like osteoporosis.

20 Nov 2020