Osteonecrosis News and Research

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New guideline focuses on the timing of hip and knee arthroplasty

The American College of Rheumatology and the American Association of Hip and Knee Surgeons released a summary of its new guideline titled "the Optimal Timing of Elective Hip or Knee Arthroplasty for Patients with Symptomatic Moderate to Severe Osteoarthritis or Osteonecrosis Who Have Failed Nonoperative Therapy."

14 Mar 2023

Unique technology uses ultrasound-responsive nanobubbles for treating osteoporosis

University of Central Florida researchers have created unique technology for treating osteoporosis that uses nanobubbles to deliver treatment to targeted areas of a person's body.

6 Dec 2022

Researchers are developing calculator that weighs risk and benefit of taking osteoporosis drugs

Osteoporosis is a major, worsening public health problem and bisphosphonates which help restore a healthier balance of bone production and resorption, have been a relatively inexpensive, successful treatment, particularly for those at highest risk for fractures.

16 Nov 2022

Landmark study finds how often cancer patients develop osteonecrosis of the jaw

A landmark study by researchers from the SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute, part of the National Institutes of Health, has found that 2.8 percent of patients on average develop osteonecrosis of the jaw, or ONJ, within three years of starting a common treatment for cancer that has spread to the bone.

17 Dec 2020

$Researchers examine the implications of bisphosphonate drug holidays on fracture risk$

Researchers examine the implications of bisphosphonate drug holidays on fracture risk

Bisphosphonates have been shown to reduce the risk of osteoporotic fractures. To avoid possible side effects of long-term therapy, many patients take a drug holiday after several years of bisphosphonate therapy.

29 Jul 2020

New tools for analyzing microbial communities

The June 2020 issue of Journal of Dental Research brings together a collection of the latest research on the oral microbiome.

22 May 2020

Steroid injections for osteoarthritis more may damage joints

Osteoarthritis (OA), also called degenerative joint disease, is the most common chronic condition of the joints. Since the disease is degenerative, it is the single most common cause of disability among older adults, with about 10 to 15 percent of all adults who are more than 60 years old have some degree of osteoarthritis, with more women affected than men.

15 Oct 2019

USC researchers report breakthrough to prevent osteonecrosis of the jaw

USC researchers and collaborators report a breakthrough to prevent damage to the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis.

11 Apr 2019

Benefits of osteoporosis treatment in postmenopausal women outweigh the perceived risks

The benefits of treating osteoporosis in postmenopausal women outweigh the perceived risks, according to a Clinical Practice Guideline issued today by the Endocrine Society. The Society introduced the guideline during a news conference on Monday at ENDO 2019, its annual meeting in New Orleans, La.

25 Mar 2019

Zoledronic acid increases disease-free survival in premenopausal women with HR+ early breast cancer

Adjuvant treatment with the bone sparing drug zoledronic acid plus hormonal therapy with the aromatase inhibitor letrozole significantly increases disease-free survival compared to tamoxifen in premenopausal women with hormone receptor positive (HR+) early breast cancer, according to results reported at ESMO 2018 Congress in Munich.

22 Oct 2018

Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

Pfizer Inc. and Eli Lilly and Company today announced that a 16-week Phase 3 study in patients with osteoarthritis pain evaluating subcutaneous administration of tanezumab, an investigational humanized monoclonal antibody, met all three co-primary endpoints.

19 Jul 2018

New technique allows researchers to create large scale, personalized bone grafts

Scientists from the New York Stem Cell Foundation Research Institute have developed a new bone engineering technique called Segmental Additive Tissue Engineering.

18 Jul 2018

Novel bioengineering technique could help repair bone defects

Researchers have developed a bone engineering technique that uses stem cells to improve bone grafts for the treatment of bone injury or disease.

18 Jul 2018

A systematic approach towards diagnosis and treatment of rheumatoid arthritis

Rheumatoid Arthritis: A systematic approach (edited by Dr. Syuichi Koarada) comprehensively covers each aspect of the pathology, diagnosis and treatment of rheumatoid arthritis.

26 Jun 2018

$Study finds incidence of fractures in 15% of osteoporosis patients who take 'drug holidays'$

Study finds incidence of fractures in 15% of osteoporosis patients who take 'drug holidays'

Patients who take osteoporosis drugs for long periods typically are advised to temporarily discontinue the drugs to prevent rare but serious side effects to the jaw and thighs.

4 May 2018

Hip replacement surgery associated with increased life expectancy, study reports

Hip replacement surgery not only improves quality of life but is also associated with increased life expectancy, compared to people of similar age and sex, reports a study in Clinical Orthopaedics and Related Research, a publication of The Association of Bone and Joint Surgeons.

28 Feb 2018

FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence

The U.S. Food and Drug Administration today approved Sutent (sunitinib malate) for the adjuvant treatment of adult patients who are at a high risk of kidney cancer (renal cell carcinoma) returning after a kidney has been removed (nephrectomy).

17 Nov 2017

Comprehensive surgical options could benefit osteoporosis patients with medication-related jaw necrosis

Osteoporosis patients who suffer drug side effects that result in painful exposed bone in the jaw could benefit if they are treated with one of the more comprehensive surgical options that could lower the risk of relapse and repeat surgery, according to a study published in the July issue of the Journal of Oral and Maxillofacial Surgery.

5 Jul 2017

Amgen, UCB present romosozumab Phase 2 results at ENDO 2017

Amgen and UCB today announced results from the fourth year of a Phase 2 study showing the efficacy and safety of a second course of treatment with EVENITY™* (romosozumab), an investigational agent for postmenopausal women with osteoporosis.

3 Apr 2017

New article outlines identical symptoms linked to hip and spine pain

Many patients live with low back pain that radiates to the buttock, groin, thigh, and even knees. The challenge for patients, and often their doctors, is determining the origin of the pain -- the hip, the spine, or both.

7 Feb 2017