Osteosarcoma News and Research

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Between two and three percent of all childhood cancers are osteosarcoma. Because osteosarcoma usually develops from osteoblasts, it most commonly affects children and young adults experiencing their adolescent growth spurt. Boys and girls have a similar incidence rate until later in their adolescence, when boys are more commonly affected. While most tumors occur in larger bones, such as the femur, tibia, and humerus, and in the area of the bone that has the fastest growth rate, they can occur in any bone. The most common symptom is pain, but swelling and limited movement can occur as the tumor grows.

Osteosarcoma is an orphan disease with approximately 1,200 new cases diagnosed in the United States each year. A similar incidence of the disease exists in Europe. According to the Children's Oncology Group (COG), the survival of children with osteosarcoma has remained at 60-65 percent since the mid-1980s. The standard treatment for osteosarcoma is tumor resection with combination chemotherapy before and after surgery.

Curing canine cancer - human cancer benefit

One of the major issues associated with longer life expectancy in man and his best friend is an increase in the incidence of cancer.

13 Jul 2007

Childhood sarcoma increases risk of blood clots

Researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, have determined that children and young adults with a form of cancer called sarcoma are at increased risk of having a thromboembolic event (TE) in their veins.

20 Apr 2007

Oncolytics Biotech to proceed with phase II Sarcoma trial

Oncolytics Biotech has announced that subsequent to the regulatory review period for this submission, it is proceeding with a Phase II trial to evaluate the intravenous administration of REOLYSIN in patients with various sarcomas that have metastasized to the lung.

11 Apr 2007

Survivors of childhood cancers have a ninefold increased risk of developing a secondary sarcoma

Treatments for childhood cancer have resulted in a current overall cure rate of over 70 percent. However, long-term survivors of childhood cancer are at a higher risk of developing a secondary cancer than the general population.

20 Feb 2007

Fewer deaths from cancer in the U.S.

According to a new report fewer Americans are dying of cancer even though the rates of new cancers remains the same.

7 Sep 2006

No alarm on fluoride: cancer risk unproven

Suggestions that fluoridated water supplies may be linked to a rare form of bone cancer have not been scientifically established, Victoria's Chief Health Officer Dr Robert Hall said this week.

20 Apr 2006

Children with bone cancer in their arms or legs survival rate improved

Ross Wilkins and Stephen Withrow are doctors working together in the fight against bone cancer. Their goals are the same. Their patients are not.

20 Apr 2006

Stem cells may cause some forms of bone cancer

The researchers are the first to identify a population of cells with characteristics of adult and embryonic stem cells in cultures derived from biopsies of patients' bone tumors. They describe their findings in the medical journal Neoplasia.

7 Dec 2005

New type of inhalation chemotherapy

Pediatric cancer specialists at The Children's Hospital at Montefiore (CHAM) are investigating a new type of inhalation chemotherapy with the potential to treat children with a deadly bone cancer that has spread to their lungs.

26 May 2005

Nuclear reactor as a cancer cure

Despite the millions of dollars that have been invested into research to improve methods of treatments for various types of cancer, oncological diseases continue to have a high mortality rate, remaining one of the main causes of death globally. Traditional cancer treatment methods, such as chemotherapy, immunotherapy, and radiotherapy are effective in approximately only half of all patients.

3 Mar 2005

Limb-sparing technique called rotationplasty helps very young children with bone cancer

The current issue of New England Journal of Medicine illustrates a case of a five-year-old girl with Ewing’s sarcoma, a cancerous tumor, behind her left knee. Surgeons at The Children’s Hospital of Philadelphia used a limb-sparing technique called rotationplasty to remove the diseased portion of bone, turn the shortened portion of the leg bone in a half-circle and reattach it, with the ankle joint functioning as a knee.

18 Aug 2004

Early patient response to Forteo in postmenopausal women with osteoporosis

Changes in markers of bone remodeling after one month of treatment with FORTEO® (teriparatide [rDNA origin] injection) may provide important early evidence of treatment response, according to new data presented today at the 86th Annual Meeting of The Endocrine Society (ENDO).

17 Jun 2004