Paclitaxel News and Research

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Paclitaxel is a drug used to treat breast cancer, ovarian cancer, and AIDS-related Kaposi sarcoma. It is also used together with another drug to treat non-small cell lung cancer. Paclitaxel is also being studied in the treatment of other types of cancer. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of antimitotic agent. Also called Taxol.

The Paclitaxel compound is extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Check for active clinical trials or closed clinical trials using this agent.
New drug-delivery system disguises chemotherapeutics as fat to outsmart tumors

New drug-delivery system disguises chemotherapeutics as fat to outsmart tumors

New drug combinations and dosing schedules improve outlook in advanced colon cancer

New drug combinations and dosing schedules improve outlook in advanced colon cancer

Processed aconite root could relieve neuropathic pain in murine peripheral neuropathy

Processed aconite root could relieve neuropathic pain in murine peripheral neuropathy

Increased stress hormones accelerate breast cancer metastasis

Increased stress hormones accelerate breast cancer metastasis

Hypertension drug may improve effectiveness of ovarian cancer treatment

Hypertension drug may improve effectiveness of ovarian cancer treatment

Clinigen, Accord Healthcare extend exclusive European clinical trial supply agreement

Clinigen, Accord Healthcare extend exclusive European clinical trial supply agreement

Study uncovers how tumors backfire on neoadjuvant chemotherapy

Study uncovers how tumors backfire on neoadjuvant chemotherapy

Study assesses safety and efficacy of new treatment for pancreatic cancer

Study assesses safety and efficacy of new treatment for pancreatic cancer

New substance could improve efficacy of established breast cancer treatments

New substance could improve efficacy of established breast cancer treatments

Two genomic tests help identify most effective treatment for breast cancer patients

Two genomic tests help identify most effective treatment for breast cancer patients

Advanced breast cancer patients can benefit from immunotherapy-chemotherapy combination

Advanced breast cancer patients can benefit from immunotherapy-chemotherapy combination

Study findings could set new standard of care for advanced anal cancer

Study findings could set new standard of care for advanced anal cancer

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Immunotherapy increases survival in some patients with metastatic triple negative breast cancer

Immunotherapy increases survival in some patients with metastatic triple negative breast cancer

Immunotherapy trial offers new hope for people with aggressive breast cancer

Immunotherapy trial offers new hope for people with aggressive breast cancer

Breast cancer survival could be extended with two new drug combinations

Breast cancer survival could be extended with two new drug combinations

Two major studies on canine cancers may provide clues on human cancers

Two major studies on canine cancers may provide clues on human cancers

Study: Chemotherapy drugs may promote muscle mitochondrial dysfunction

Study: Chemotherapy drugs may promote muscle mitochondrial dysfunction

Researchers take first steps in developing 'paintable' chemotherapy for melanoma

Researchers take first steps in developing 'paintable' chemotherapy for melanoma

Researchers discover novel targeting agents to prevent cancer metastasis

Researchers discover novel targeting agents to prevent cancer metastasis