Paclitaxel News and Research

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Paclitaxel is a drug used to treat breast cancer, ovarian cancer, and AIDS-related Kaposi sarcoma. It is also used together with another drug to treat non-small cell lung cancer. Paclitaxel is also being studied in the treatment of other types of cancer. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of antimitotic agent. Also called Taxol.

The Paclitaxel compound is extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Check for active clinical trials or closed clinical trials using this agent.
Trastuzumab combined with trimodality treatment for HER2-overexpressing esophageal cancer found to be ineffective

Trastuzumab combined with trimodality treatment for HER2-overexpressing esophageal cancer found to be ineffective

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

BAK/MCL1 complex in tumor cells can predict the sensitivity of chemotherapy drugs in ovarian cancer

BAK/MCL1 complex in tumor cells can predict the sensitivity of chemotherapy drugs in ovarian cancer

New genetic classifier can predict the sensitivity of neoadjuvant chemotherapy for breast cancer

New genetic classifier can predict the sensitivity of neoadjuvant chemotherapy for breast cancer

Combination of metformin and chemoradiation does not add survival benefit in patients with LA-NSCLC

Combination of metformin and chemoradiation does not add survival benefit in patients with LA-NSCLC

Innovative testing platform could enable more precise, personalized immunotherapy

Innovative testing platform could enable more precise, personalized immunotherapy

Antagonism of glucocorticoid receptors promotes apoptosis in solid tumor cells

Antagonism of glucocorticoid receptors promotes apoptosis in solid tumor cells

Combination of anti-HER2 breast cancer therapy and checkpoint inhibitor provides no benefit

Combination of anti-HER2 breast cancer therapy and checkpoint inhibitor provides no benefit

SWOG researchers to present practice-changing research at virtual ASCO 2021

SWOG researchers to present practice-changing research at virtual ASCO 2021

Lengthy treatment with low-dose 6-mercaptopurine inhibits resistant triple-negative breast cancer cells

Lengthy treatment with low-dose 6-mercaptopurine inhibits resistant triple-negative breast cancer cells

Study: No major difference in mortality between patients treated with drug-coated and non-drug-coated devices

Study: No major difference in mortality between patients treated with drug-coated and non-drug-coated devices

New strategy could increase the effectiveness of chemotherapy treatments

New strategy could increase the effectiveness of chemotherapy treatments

Drug synthesized from Kentucky-grown plant shows promise in treating ovarian cancer

Drug synthesized from Kentucky-grown plant shows promise in treating ovarian cancer

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

The Dream Team opens clinical trial to find better treatment options for pancreatic cancer

The Dream Team opens clinical trial to find better treatment options for pancreatic cancer

Study reveals potential risk factors for developing nerve damage after cancer treatment

Study reveals potential risk factors for developing nerve damage after cancer treatment

Combining PD-1 and VEGF inhibitors with chemotherapy can help control cholangiocarcinoma

Combining PD-1 and VEGF inhibitors with chemotherapy can help control cholangiocarcinoma

Combination therapy places no greater burden on early-stage breast cancer patients

Combination therapy places no greater burden on early-stage breast cancer patients

Study: Paclitaxel-coated devices do not increase mortality for patients with peripheral artery disease

Study: Paclitaxel-coated devices do not increase mortality for patients with peripheral artery disease

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

First-ever phase 3 advanced anal cancer trial opens for patient enrollment