Pharmacokinetics News and Research

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The term pharmacokinetics is derived from the ancient Greek words “pharmakon” and “kinetikos”, meaning “drug” and “putting in motion” respectively. It is one of the main branches of pharmacology, and refers to the way that the body reacts on and affects a pharmaceutical substance in the body.

Accelerator Life Science Partners launches new company to develop novel therapy for seizure disorders

Accelerator Life Science Partners (Accelerator), a leading life science investment and management firm, today announced that it has launched Proniras Corporation, a company developing tezampanel for the treatment of a variety of seizure disorders.

27 Apr 2018

KU Cancer Center to present evidence supporting anti-cancer drug at AACR 2018

The University of Kansas Cancer Center will present preclinical evidence supporting Ciclopirox Prodrug (CPX-POM), an anti-cancer agent currently in Phase I clinical trials, at the American Association for Cancer Research 2018 Annual Meeting in Chicago. Ciclopirox Prodrug was discovered by researchers at The University of Kansas Cancer Center and KU's Institute for Advancing Medical Innovation.

12 Apr 2018

New total-body PET scanner could revolutionize patient diagnosis and care

The new total-body PET/CT scanner could revolutionize our understanding and treatment of disease through analysis of better imaging data from the whole body.

3 Jan 2018

IPM begins first clinical trial of vaginal rings to prevent HIV in women

The nonprofit International Partnership for Microbicides announced today the start of the first clinical trial of vaginal rings designed to slowly release the antiretroviral drug dapivirine over three months to prevent HIV in women.

13 Dec 2017

New, more easily administered therapies offer benefits for bleeding and clotting disorders

In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits from new, more easily administered therapies for bleeding and clotting disorders.

11 Dec 2017

Women have lower tolerance to alcohol following gastric sleeve surgery, study finds

Women who have had gastric sleeve surgery to lose weight may want to consider limiting the number of alcoholic drinks they consume post-surgery.

20 Nov 2017

Adipocytes may reduce effectiveness of chemotherapeutic drug

Adipocytes, or fat cells, can absorb and metabolize the chemotherapeutic agent daunorubicin, reducing the effectiveness of the drug and potentially contributing to poorer treatment outcomes.

8 Nov 2017

An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections

There are about 77,000 people known to have cystic fibrosis. That's from the various cystic fibrosis registries available globally. The World Health Organization suggests that this number may be low, because there's no reporting on cystic fibrosis from the developing world. The accepted number, at the moment, is about 80,000. That's the one that is used for most of the work that's being done on cystic fibrosis.

From Neem Biotech 3 Nov 2017

Bioengineers develop brain sensor technique to understand cocaine addiction in adolescent mind

Several studies have provided strong evidence that adolescents--people in their teens to early twenties--have a higher vulnerability than adults to addictive substances like cocaine.

1 Nov 2017

Trial shows safety and tolerability of antisense oligomer for treatment of influenza A

A phase 1 clinical trial published in the British Journal of Clinical Pharmacology found that radavirsen -- an antisense oligomer that inhibits the production of certain influenza proteins -- is safe and well-tolerated in healthy individuals.

20 Sep 2017

Researchers reveal new approach to precisely identify and treat prostate cancer

Researchers have demonstrated a new, effective way to precisely identify and localize prostate cancer tumors while protecting healthy tissue and reducing side effects.

7 Sep 2017

St. Jude creates world’s largest collection of pediatric solid tumor samples

In an effort to improve outcomes for patients with some of the deadliest childhood cancers, St. Jude Children's Research Hospital scientists have created the world's largest collection of pediatric solid tumor samples, drug-sensitivity data and related information and have made the resource available at no charge to the global scientific community.

31 Aug 2017

FDA grants accelerated approval to new treatment for children with Chagas disease

The U.S. Food and Drug Administration today granted accelerated approval to benznidazole for use in children ages 2 to 12 years old with Chagas disease. It is the first treatment approved in the United States for the treatment of Chagas disease.

29 Aug 2017

Critical research strategies and interventions established for pediatric and adolescent HIV

The highest priority research agendas needed to improve the testing and treatment of children and adolescents with HIV were presented at the 9th International Aids Society (IAS) Conference on HIV Science in Paris this weekend.

24 Jul 2017

Scientists create new probe for imaging proteins involved in fibrogenesis

Organs respond to injuries with the formation of new fibrous tissue, which can result in scarring. This process called fibrogenesis can now be monitored noninvasively on a molecular level, as American scientists report in the journal Angewandte Chemie.

19 Jul 2017

Study finds link between upper GI infections and protein implicated in Parkinson’s disease

Acute and chronic infections in a person's upper gastrointestinal tract appear to be linked to Parkinson's disease, say scientists at Georgetown University Medical Center and their collaborators at the National Institutes of Health and other institutions.

28 Jun 2017

Antibiotic resistance: a healthcare emergency?

Antibiotic resistance is happening in hospitals quite frequently. Probably the main place where resistant organisms and pathogens are acquired is in intensive care units (ICUs).

26 Jun 2017

New position paper recommends sex-specific cardiovascular drug dosages for better treatment

Sex-specific cardiovascular drug dosages are needed to reduce adverse reactions in women, according to a position paper from the European Society of Cardiology published today in the June issue of European Heart Journal - Cardiovascular Pharmacotherapy.

15 Jun 2017

Study describes synthesis and biological evaluation of novel, effective ARIs

Diabetes mellitus (DM) is probably one of the oldest known diseases and the incidence has been increasing steadily all over the world. This metabolic disease is characterized by chronic hyperglycemia due to defect in insulin secretion and/or insulin action.

17 Apr 2017

FDA grants approval for two drugs to treat hepatitis C virus in children

The U.S. Food and Drug Administration today approved supplemental applications for Sovaldi (sofosbuvir) and Harvoni (ledipasvir and sofosbuvir) to treat hepatitis C virus (HCV) in children ages 12 to 17. Harvoni and Sovaldi were previously approved to treat HCV in adults.

7 Apr 2017