Plague News and Research

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Tobacco use poses major health and human development threat

If the word's nations are going to prevent tobacco smoking from causing one projected billion deaths by the end of this century, they must: Make tobacco control part of the agendas of United Nation's and other development agencies worldwide; Assure every sector of a nation including health, trade and finance officials work collectively to protect not only health but the harm tobacco places on their economy by passing laws to reduce use; Place health as the centerpiece of any decision on a trade treaty that includes tobacco; Diligently work toward a goal of reducing the prevalence rate of smoking to less than five percent world-wide by 2048, basically ending its use.

5 Mar 2013

Inviragen to initiate second stage of DENVax Phase 2 study in dengue

Inviragen, Inc. today announced the initiation of the second stage of an ongoing Phase 2, randomized, double-blind, placebo-controlled study of DENVax, the Company's investigational dengue vaccine.

27 Feb 2013

Princeton metabolic model can predict how parasites would fare in altered climates

Knowing the temperatures that viruses, bacteria, worms and all other parasites need to grow and survive could help determine the future range of infectious diseases under climate change, according to new research.

27 Feb 2013

Conference aims to end tobacco epidemic in developing nations

Imagine, for a moment, that a plague has ravaged the Developed World, but has not yet established its grip on the Developing Nations. If the world's leaders in public health came together for two days at Harvard to map out a campaign to prevent the plague's spread, wouldn't you want to cover that meeting?

26 Feb 2013

BCHE gene variant predicts extent of plaque deposits in Alzheimer's

A study combining genetic data with brain imaging, designed to identify genes associated with the amyloid plaque deposits found in Alzheimer's disease patients, has not only identified the APOE gene -- long associated with development of Alzheimer's -- but has uncovered an association with a second gene, called BCHE.

21 Feb 2013

Environmental factors may explain plague re-emergence in northern Africa

Two recent outbreaks of plague in Libya and Algeria are likely due to re-emergence or re-activation of ancient Yersinia pestis from the local area, rather than recent importation from the same distant source, suggest study findings.

17 Jan 2013

Wall Street Journal looks at European efforts to fight TB

The Wall Street Journal examines efforts to fight tuberculosis (TB) in Europe, writing, "All along the edges of Western Europe, new and hard-to-defeat strains of tuberculosis are gaining a foothold, often moving beyond traditional victims -- alcoholics, drug users, HIV patients -- and into the wider population."

3 Jan 2013

Scientists discover how Yersinia pestis avoids setting off immune system's early infection-alarm

The plague-causing bacteria Yersinia pestis evades detection and establishes a stronghold without setting off the body's early alarms.

14 Dec 2012

Researchers describe role of calcium in ability of Yersinias to cause disease

A more than 50-year-old question has now been answered. Chemists and microbiologists at the Biological Chemistry Center at Umeå University in Sweden are now able to describe in detail the role of calcium in the ability of the plague bacterium Yersinias to cause disease.

4 Dec 2012

Broad range of human activities affects spread of vector-borne zoonotic diseases, experts say

West Nile virus, Lyme disease, dengue fever, and plague are examples of "vector-borne zoonotic diseases," caused by pathogens that naturally infect wildlife and are transmitted to humans by vectors such as mosquitoes or ticks.

30 Nov 2012

Aradigm’s Lipoquin provides full protection in murine models of pneumonic plague

Scientists from the UK Defence Science and Technology Laboratory (Dstl) report, in a preliminary study, that they have demonstrated that a single dose of Aradigm Corporation's liposomal ciprofloxacin formulation Lipoquin administered 24 hours after exposure to a lethal dose of the bacterium Yersinia pestis provided full protection in a murine model of pneumonic plague.

20 Nov 2012

Injury prevention – research and practice: an interview with Dr Dale Hanson

Every twenty seconds someone somewhere in Australia presents to an Emergency Department seeking treatment for an injury. Every minute someone is admitted to hospital. Every hour someone dies.

13 Nov 2012

Most compounding pharmacies are not accredited

News outlets, following the story about a deadly meningitis outbreak linked to drugs provided by a compounding pharmacy, explore the issue of accreditation, how many more people are at risk and what leads doctors to use these drugs.

20 Oct 2012

Enrollment complete in Resverlogix‘s RVX-208 Phase 2b trial on cardiovascular disease

Resverlogix Corp. today announced that it has completed enrollment in ASSURE, a Phase 2b clinical trial targeting high-risk cardiovascular disease patients.

27 Sep 2012

Study finds four different subtypes of breast cancer

In a study published by the journal Nature on Sunday, scientists evaluated breast cancer from a genetic perspective and found distinct genetic differences in patients' tumors. The results of the research point to the fact that analyzing genetics is not only helpful for cancer research, but imperative. Based on the study, scientists conclude that breast cancer can be broken down into four different subtypes.

26 Sep 2012

Detect-to-Protect project to measure performance of new sensors for biological agents

The idea that disease and infection might be used as weapons is truly dreadful, but there is plenty of evidence showing that biological weapons have been around since ancient times. Bioterrorism, as it is dubbed, is nothing new, and although medicines have made the world a safer place against a myriad of old scourges both natural and manmade, it still remains all too easy today to uncork a nasty cloud of germs.

27 Aug 2012

Mali faces 'complex humanitarian emergency' as a result of displacement, food insecurity

"More than 435,000 people have been displaced in Mali, as the country faces a complex humanitarian emergency due to conflict and food insecurity, according to a new report released by the United Nations relief agency," the U.N. News Centre reports.

21 Aug 2012

New method gives precise picture of how immune system works

Chronic infections are a large and growing problem throughout the developed world, and intensive research is being conducted in ways to combat the recalcitrant bacteria. When bacteria aggregate into so-called biofilm, they become resistant to antibiotics. Until now scientists have only been able to speculate about what happens when bacteria overpower the immune system during a chronic infection.

9 Aug 2012

Viewpoints: Mass. at disadvantage in cutting health costs; McDonnell says Va. can point to better way

Massachusetts will be the first state to try to cap overall health care spending, both private and public, so that it will grow no faster than the state economy. The state was able to reach near-universal coverage because the vast majority of its population was already covered by some form of insurance. It also could subsidize coverage for the uninsured using a big pool of money that had been used for charity care. But when it comes to controlling health care costs, Massachusetts has no advantage, and in fact is starting behind most other states.

7 Aug 2012

Scientists identify biological mechanism that may be responsible for icy extremities

Cold feet-those chilly appendages that plague many people in the winter and an unlucky few all year round-can be the bane of existence for singles and couples alike. In a new study, scientists led by Selvi C. Jeyaraj of the Research Institute at Nationwide Children's Hospital have identified a biological mechanism that may be responsible for icy extremities: an interaction between a series of molecules and receptors on smooth muscle cells that line the skin's tiny blood vessels.

1 Aug 2012