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Researchers demonstrate how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

6 Apr 2022

Investigating high rate of Omicron sublineage breakthrough infections in triple vaccinated healthcare workers

Researchers identified breakthrough infections by Omicron sublineages BA.1, BA.1.1, and BA.2 in triple-vaccinated healthcare workers of Sweden.

6 Apr 2022

Researchers explore the link between immunoglobulins and blood profile in severe SARS-CoV-2 patients

A new study illustrated the association of immunoglobulins with blood characteristics in COVID-19 patients.

6 Apr 2022

SARS-CoV-2 transmission from human to free-roaming dogs during a severe COVID-19 outbreak in the Amazonian Region of Ecuador

A new study shows how free-roaming village dogs in an Ecuadorian village within the Amazon jungle have been infected with the virus, presumably by the human hosts.

6 Apr 2022

Study evaluates the presence of the SARS-CoV-2 spike protein in urine samples collected during the COVID-19 pandemic

A study published analyzed the presence of SARS-CoV-2 spike protein in urine samples of the infected patients.

6 Apr 2022

Study says duplilumab reduces mortality from COVID-19

A recent report posted to the medRxiv* preprint server assessed the efficacy of dupilumab in blocking the IL-13 signaling pathway and its efficacy in reducing the COVID-19 associated mortality.

5 Apr 2022

Do androgens play a role in COVID-19 severity?

Researchers assess the association between the AR polyQ polymorphism with COVID-19 severity using a large cohort of 1,136 COVID-19 male patients.

5 Apr 2022

Swedish HCW study shows COVID booster shots have limited effect on Omicron

Researchers examine emerging infections in healthcare workers who received the booster vaccination either with or without prior SARS-CoV-2 infection.

5 Apr 2022

Does COVID-19 vaccination benefit those with prior SARS-CoV-2 infection?

Researchers evaluate the effectiveness of four COVID-19 vaccines against symptomatic infection, hospitalization, and death in convalescent individuals.

5 Apr 2022

Pre-existing memory B cell dynamics during SARS-CoV-2 Omicron breakthrough infection

A new study analyzed the recall of pre-existent cross-reactive memory B cells upon the SARS-CoV-2 Omicron breakthrough infections.

5 Apr 2022

Study investigates the local-mucosal susceptibility and innate immune response to Omicron compared to other variants

A recent study observed that the replication of the SARS-CoV-2 Omicron variant was restricted in human lung tissues

5 Apr 2022

Study demonstrates cross-neutralization among SARS-CoV-2 Omicron sublineages

Researchers assessed the cross-neutralization among three sublineages of the SARS-CoV-2 Omicron variant: BA.1, BA.2, and BA.3 sublineages, and an additional strain, USA/WA1-2020 (wild-type) in mice.

5 Apr 2022

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

A recent study investigated the impact of a recombinant fragment of cellular glycoprotein Gal-3BP on IL-6 expression in acute COVID-19.

5 Apr 2022

Effectiveness of COVID-19 vaccines against hospitalization in those testing positive for Omicron and Delta variants

A recent study assessed the effectiveness of SARS-CoV-2 vaccines against the hospitalization of infected patients.

5 Apr 2022

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Researchers profiled cardiac tissue transcriptomes of COVID-19 patients.

5 Apr 2022

Study detects SARS-CoV-2 BA.1/BA.2 recombinant in two epidemiologically linked cases

Researchers have focussed on detecting BA.1/BA.2 recombinant in travelers through surveillance.

5 Apr 2022

Framework for genomic surveillance of SARS-CoV-2 Mpro evolution

A recent study posted to the bioRxiv* preprint server investigated the active genetic evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), its emerging mutations, and the existence of antiviral resistance against Mpro inhibitors like paxlovid.

5 Apr 2022

Study on the efficacy of a BNT162b2 booster dose in the elderly

In a recent study posted to the medRxiv* preprint server, researchers characterized the immune responses against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant after receiving a booster dose of BNT162b2 vaccine in older people.

5 Apr 2022

Air surveillance of SARS-CoV-2 and other respiratory pathogens

A recent study posted to the medRxiv* preprint server reported severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) detection in air samples from real-world congregate settings.

4 Apr 2022

SARS-CoV-2 prevalence during the initial period of SARS-CoV-2 Omicron variant emergence in Finland

A recent study presented the rapid spike in COVID-19 seroprevalence during the emergence of the Omicron variant in Finland.

4 Apr 2022

Polymerase News and Research

Researchers demonstrate how a narrow-spectrum antibiotic selectively targets C. diff

Investigating high rate of Omicron sublineage breakthrough infections in triple vaccinated healthcare workers

Researchers explore the link between immunoglobulins and blood profile in severe SARS-CoV-2 patients

SARS-CoV-2 transmission from human to free-roaming dogs during a severe COVID-19 outbreak in the Amazonian Region of Ecuador

Study evaluates the presence of the SARS-CoV-2 spike protein in urine samples collected during the COVID-19 pandemic

Study says duplilumab reduces mortality from COVID-19

Do androgens play a role in COVID-19 severity?

Swedish HCW study shows COVID booster shots have limited effect on Omicron

Does COVID-19 vaccination benefit those with prior SARS-CoV-2 infection?

Pre-existing memory B cell dynamics during SARS-CoV-2 Omicron breakthrough infection

Study investigates the local-mucosal susceptibility and innate immune response to Omicron compared to other variants

Study demonstrates cross-neutralization among SARS-CoV-2 Omicron sublineages

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

Effectiveness of COVID-19 vaccines against hospitalization in those testing positive for Omicron and Delta variants

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Study detects SARS-CoV-2 BA.1/BA.2 recombinant in two epidemiologically linked cases

Framework for genomic surveillance of SARS-CoV-2 Mpro evolution

Study on the efficacy of a BNT162b2 booster dose in the elderly

Air surveillance of SARS-CoV-2 and other respiratory pathogens

SARS-CoV-2 prevalence during the initial period of SARS-CoV-2 Omicron variant emergence in Finland

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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