Polymerase News and Research

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Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

In a recent study posted to the bioRxiv* preprint server, researchers test three severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals authorized for emergency use by the United States Food and Drug Administration (FDA) for their in vitro potency against several SARS-CoV-2 variants, including the currently dominant Omicron train.

23 Jan 2022

Novel SARS-CoV-2 mutations reported in chronic HIV patients

A new study describes the emergence of new SARS-CoV-2 variants in three immunocompromised patients.

23 Jan 2022

SARS-CoV-2 Omicron associated with fewer lower and more upper respiratory tract symptoms

Researchers assess the impact of the SARS-CoV-2 Omicron variant of concern on symptoms of SARS-CoV-2 infection.

23 Jan 2022

SARS-CoV-2 prevalence in bivalve mollusks from harvesting areas in Southern Italy

The goal of the current study was to collect data on the prevalence of SARS-CoV-2 in bivalve mollusks harvested in the Campania region using dd RT-PCR for the detection of low levels of virus in mollusk tissues.

21 Jan 2022

Study suggests SARS-CoV-2 Omicron variant spike mediated immune escape and tropism shift

A new study showed that the SARS-CoV-2 Omicron spike binds to its receptor with enhanced affinity and yet evades vaccine-elicited neutralizing antibodies and that a booster mRNA vaccine broadened the neutralization of Omicron.

21 Jan 2022

A validated risk-stratification system to manage COVID-19 outpatients

A group of researchers developed a risk-stratification system from existing scoring methods that are exclusively for outpatients.

20 Jan 2022

Indian study suggests significant decrease in protection from vaccine or natural immunity against Omicron variant

Researchers present evidence for early community transmission of the SARS-CoV-2 Omicron variant in New Delhi, India.

20 Jan 2022

Determining COVID-19 vaccine effectiveness among health care workers in Wales

A new study revealed an overall high vaccine uptake and significant vaccine effectiveness of BNT162b2 against COVID-19, among healthcare workers in Wales.

20 Jan 2022

Is COVID-19 mRNA vaccination in children associated with subsequent multisystemic hyper-inflammatory syndrome?

Researchers assessed the possibility of COVID-19 mRNA vaccines causing multisystem inflammatory syndrome in children aged 12 to 17 years in France.

20 Jan 2022

A novel assay for the rapid detection of SARS-CoV-2 variants

A new study discusses a new assay method designed by researchers to identify SARS-CoV-2 variants.

20 Jan 2022

Virucidal effect of UV and violet light on SARS-CoV-2

In a recent study published in the Journal of Photochemistry and Photobiology, a team of researchers analyzed the effect of ultraviolet (UV) and violet light of different wavelengths on the virulence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

20 Jan 2022

Females more prone to long-term post-COVID-19 symptoms

In a recent study published in the Journal of Clinical Medicine, researchers described the results of a multi-center study (LONG-COVID-EXP-CM) that investigated sex differences in coronavirus disease 2019 (COVID-19)-related symptoms and long-term post-COVID-19 symptoms in a group of previously hospitalized COVID-19 survivors in a large Spanish population.

19 Jan 2022

SARS-CoV-2 RNA can be detected in exhaled aerosol

In a study published in the open-access journal Influenza and other Respiratory Viruses, researchers investigated if severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be detected in exhaled aerosol samples obtained from coronavirus disease 2019 (COVID-19) patients during many different types of breathing and coughing. They also analyzed how SARS-CoV-2 infection may affect the size and number of exhaled aerosol particles.

19 Jan 2022

Emerging nanomaterials-based biosensor for detecting SARS-CoV-2

A new study aimed to highlight the different smart and emerging nanomaterials used to detect SARS-CoV-2.

19 Jan 2022

Study shows inequalities in addressing post-acute neurological manifestations of COVID-19

Researchers have explored the inequities in understanding and addressing the neurological complications of COVID-19 among marginalized communities in the United States.

19 Jan 2022

Impact of COVID-19 on male and female reproductive health

A new review article investigated the relation between SARS-CoV-2 infection and reproductive health.

19 Jan 2022

Wastewater-based epidemiology to predict emerging new SARS-CoV-2 variants

In a new study, researchers established a strong approach for deducing public health-relevant epidemiological metrics like relative variant abundance and variant-specific reproduction numbers from wastewater (WW)-derived deep sequenced SARS-CoV-2 genomes.

18 Jan 2022

Polymerase News and Research

Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

Novel SARS-CoV-2 mutations reported in chronic HIV patients

SARS-CoV-2 Omicron associated with fewer lower and more upper respiratory tract symptoms

SARS-CoV-2 prevalence in bivalve mollusks from harvesting areas in Southern Italy

Study suggests SARS-CoV-2 Omicron variant spike mediated immune escape and tropism shift

A validated risk-stratification system to manage COVID-19 outpatients

Indian study suggests significant decrease in protection from vaccine or natural immunity against Omicron variant

Determining COVID-19 vaccine effectiveness among health care workers in Wales

Is COVID-19 mRNA vaccination in children associated with subsequent multisystemic hyper-inflammatory syndrome?

A novel assay for the rapid detection of SARS-CoV-2 variants

Virucidal effect of UV and violet light on SARS-CoV-2

Females more prone to long-term post-COVID-19 symptoms

SARS-CoV-2 RNA can be detected in exhaled aerosol

Emerging nanomaterials-based biosensor for detecting SARS-CoV-2

Study shows inequalities in addressing post-acute neurological manifestations of COVID-19

Impact of COVID-19 on male and female reproductive health

Wastewater-based epidemiology to predict emerging new SARS-CoV-2 variants

Analyzing disease severity of SARS-CoV-2 Omicron variant using RNA dependent RNA polymerase target delay

Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics

Officials struggle to regulate pop-up covid testing sites — and warn patients to beware

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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