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Healthcare workers at increased SARS-CoV-2 infection risk during second wave

A new study evaluates the SARS-CoV-2 infection rates among healthcare workers during the second wave of the COVID-19 pandemic.

24 Nov 2021

Markers of SARS-CoV-2 shedding in vaccinated and unvaccinated individuals

The study uses serial mid-turbinate nasal specimens collected from a subset of incarcerated persons infected during this outbreak.

24 Nov 2021

Limited immune responses three months after Pfizer-BioNTech vaccination among elderly

In this study, published on the medRxiv* preprint server, the humoral response to SARS-CoV-2 was assessed before and after three months of administration of the BNT162b2 mRNA COVID-19 vaccination (Pfizer-BioNTech). In addition, elders' humoral responses were compared to those of a younger group, and a functional neutralization experiment against the Wuhan-Hu-1 (WH1) virus and the Delta variant was carried out.

23 Nov 2021

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

Study shows risk of MIS-C post mRNA vaccination against COVID-19 in children with autoimmune complications

Researchers discuss two cases of MIS-V after the patients had received the SARS-CoV-2 vaccine from Pfizer/BioNTech (BNT162b2).

23 Nov 2021

An increase in the half-life of remdesivir for COVID-19 treatment

In this study, researchers analyzed several drug candidates to investigate their efficacy against a broad spectrum of coronaviruses in cell culture studies.

23 Nov 2021

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

Turkish researchers discuss their rapid electrochemical biosensing platform to detect the SARS-CoV-2 spike antibody.

22 Nov 2021

Success of covid antiviral pills hinges on access to speedy and accurate tests

Within a few weeks, perhaps before many Americans finish decorating for the holidays, the U.S. could have access to a new antiviral pill from Merck expected to alter the deadly trajectory of the covid-19 pandemic — with a second option from Pfizer to follow shortly after.

22 Nov 2021

Effectiveness of COVID-19 vaccination during Delta variant predominance

A new study investigated the continued effectiveness of COVID-19 vaccination during the delta variant predominance in a diverse and urban healthcare setting.

19 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Viral biomolecular condensation

A review published in PLOS Pathogens deconstructs virus condensation and provides a biochemical background for LLPS.

19 Nov 2021

Air filter and floor sampling to detect SARS-CoV-2 RNA in schools

A study recently published on the medRxiv* preprint server observed the presence of SARS-CoV-2 RNA in five schools (96 classrooms) in Davis, California (USA), by collecting weekly surface-swab samples from classroom floors and/or portable high-efficiency particulate air (HEPA) units.

18 Nov 2021

REGEN-COV is effective in preventing severe COVID-19 in immunocompromised individuals

A recent study assesses the efficacy of repeat doses of REGEN-COV in SARS-CoV-2-negative adults who were healthy or had chronic medical conditions.

18 Nov 2021

SARS-CoV-2 infection and reinfection in farmed mink

A new study finds that farmed mink acquire SARS-CoV-2 infection, freely transmit it among themselves, and were reinfected, despite being seropositive.

18 Nov 2021

Evidence of significantly greater protection against COVID from BNT162b2 boosters

In a new study, researchers from several British institutes estimated the effectiveness of booster vaccination against symptomatic COVID-19 in adults aged 50 years and older.

18 Nov 2021

New method to identify potential false-positive COVID-19 results

Researchers from the University of Missouri School of Medicine have developed and tested a process to identify potential false-positive COVID-19 results.

17 Nov 2021

SARS-CoV-2 reinfection associated with housing instability

Researchers examine the impact of demographic factors and antibody responses following SARS-CoV-2 reinfection.

17 Nov 2021

Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

A new study published in the journal Diagnostics was based on the hypothesis that detecting urinary SARS-CoV-2 nucleic acid––which may result in renal and cardiovascular endothelial destruction to facilitate viral access to the kidney parenchyma—may be used as a specific biomarker to indicate the severity of COVID-19.

16 Nov 2021